Z
Zdenka Navratilova
Researcher at Palacký University, Olomouc
Publications - 31
Citations - 485
Zdenka Navratilova is an academic researcher from Palacký University, Olomouc. The author has contributed to research in topics: Single-nucleotide polymorphism & Population. The author has an hindex of 10, co-authored 29 publications receiving 408 citations. Previous affiliations of Zdenka Navratilova include Karolinska Institutet.
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Journal ArticleDOI
Matrix Metalloproteinases and Their Inhibitors in Chronic Obstructive Pulmonary Disease.
TL;DR: The data from longitudinal prospective studies on the MMP/TIMP network may lead to the introduction of novel prognostic biomarkers into clinical management of COPD, and the involvement of microRNAs is described.
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Polymorphisms in CCL2&CCL5 chemokines/chemokine receptors genes and their association with diseases.
TL;DR: Recent advance in the identification of chemokine genetic background of the diseases could provide opportunity for pharmacological treatment, however, more information about posttranscriptional events is needed to understand functional relevance of polymorphisms and to discovery new avenues to blocking disease development.
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High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences
Natalia V. Rivera,Marcus Ronninger,Klementy Shchetynsky,Andre Franke,Markus M. Nöthen,Joachim Müller-Quernheim,Stefan Schreiber,Indra Adrianto,Bekir Karakaya,Coline H.M. van Moorsel,Zdenka Navratilova,Vitezslav Kolek,Benjamin A. Rybicki,Michael C. Iannuzzi,Martin Petrek,Jan C. Grutters,Courtney G. Montgomery,Annegret Fischer,Anders Eklund,Leonid Padyukov,Johan Grunewald +20 more
TL;DR: Comprehensive and integrative analyses of genetics, transcription, and pathway modeling on LS and non-LS indicates that these sarcoidosis phenotypes have different genetic susceptibility, genomic distributions, and cellular activities, suggesting distinct molecular mechanisms in pathways related to immune response with a common region.
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Simultaneous up-regulation of matrix metalloproteinases 1, 2, 3, 7, 8, 9 and tissue inhibitors of metalloproteinases 1, 4 in serum of patients with chronic obstructive pulmonary disease
TL;DR: The serum profile of MMP 1–3, 7–9, 12 and 13, and TIMP 1–4 in COPD patients is investigated.
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PSMB2 and RPL32 are suitable denominators to normalize gene expression profiles in bronchoalveolar cells
Eva Kriegova,Arsen Arakelyan,Regina Fillerova,Jaromir Zatloukal,Frantisek Mrazek,Zdenka Navratilova,Vitezslav Kolek,Roland M. du Bois,Martin Petrek +8 more
TL;DR: PSMB2 and RPL32 are suitable reference genes to normalize qRT-PCR in BAL cells in sarcoidosis, and other interstitial lung disease.