Z
Zhaoxia Li
Researcher at University of Washington
Publications - 2
Citations - 4509
Zhaoxia Li is an academic researcher from University of Washington. The author has contributed to research in topics: Interleukin 21 & Cytotoxic T cell. The author has an hindex of 2, co-authored 2 publications receiving 4230 citations.
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Journal ArticleDOI
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Heon Park,Zhaoxia Li,Xuexian O. Yang,Seon Hee Chang,Roza Nurieva,Yi Hong Wang,Ying Wang,Leroy Hood,Zhou Zhu,Qiang Tian,Chen Dong +10 more
TL;DR: In vivo, antibody to IL- 17 inhibited chemokine expression in the brain during experimental autoimmune encephalomyelitis, whereas overexpression of IL-17 in lung epithelium caused Chemokine production and leukocyte infiltration, indicating a unique T helper lineage that regulates tissue inflammation.
Journal ArticleDOI
Murine B7-H3 is a negative regulator of T cells.
TL;DR: It was found that mouse B7-H3 protein inhibited T cell activation and effector cytokine production and led to exacerbated experimental autoimmune encephalomyelitis in vivo.