Z
Zhen Zhu
Researcher at Chinese Center for Disease Control and Prevention
Publications - 63
Citations - 2033
Zhen Zhu is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Rubella & Measles. The author has an hindex of 22, co-authored 63 publications receiving 1730 citations.
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An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of hand foot and mouth disease in Fuyang city of China.
Yan Zhang,Zhen Zhu,Weizhong Yang,Jun Ren,Xiaojuan Tan,Yu Wang,Naiying Mao,Songtao Xu,Shuangli Zhu,Aili Cui,Yong Zhang,Dongmei Yan,Qun Li,Xiao-Ping Dong,Jing Zhang,Yueping Zhao,Junfeng Wan,Zijian Feng,Junling Sun,Shiwen Wang,Dexin Li,Wenbo Xu +21 more
TL;DR: An emerging recombinant HEV71 was responsible for the HFMD outbreak in Fuyang City of China, 2008, and was confirmed as the etiological pathogen of the outbreak.
Journal ArticleDOI
Outbreak of Acute Respiratory Disease in China Caused by B2 Species of Adenovirus Type 11
Zhen Zhu,Yong Zhang,Songtao Xu,Pengbo Yu,Xiaoping Tian,Li Wang,Zhonghua Liu,Liuying Tang,Naiying Mao,Yixin Ji,Chong-Shan Li,Zhaohui Yang,Zhaohui Yang,Shiwen Wang,Jing-Jun Wang,Dexin Li,Wenbo Xu +16 more
TL;DR: The results of direct reverse transcription-PCR or PCR performed with clinical specimens collected from the patients, including the sole patient who died, were positive for human adenoviruses but negative for influenza virus, measles virus, rubella virus, mumps virus, parainfluenza virus, respiratory syncytial virus, and human enterovirus.
Journal ArticleDOI
Retrospective seroepidemiology indicated that human enterovirus 71 and coxsackievirus A16 circulated wildly in central and southern China before large-scale outbreaks from 2008
Zhen Zhu,Shuangli Zhu,Xue-bin Guo,Xue-bin Guo,Jitao Wang,Jitao Wang,Dongyan Wang,Dongmei Yan,Xiaojuan Tan,Liuying Tang,Hui Zhu,Zhaohui Yang,Zhaohui Yang,Xiaohong Jiang,Yixin Ji,Yong Zhang,Wenbo Xu +16 more
TL;DR: It is confirmed that HEV71 and CVA16 had wildly circulated in a couple provinces in China before the large-scale outbreaks from 2008, and public health measures to control the spread should be devised according to the different regional characteristics.
Journal ArticleDOI
Emergence of community-acquired adenovirus type 55 as a cause of community-onset pneumonia.
Bin Cao,Guohong Huang,Zeng-Hui Pu,Jiuxin Qu,Xiaomin Yu,Zhen Zhu,Jian-Ping Dong,Yan Gao,Yong-xiang Zhang,Xiao-Hui Li,Jian-hua Liu,Hong Wang,Qian Xu,Hui Li,Wenbo Xu,Chen Wang +15 more
TL;DR: HAdV-55 has established itself as a major pneumonia pathogen in the Chinese population, and further surveillance and monitoring of this agent as a cause of CAP is warranted.
Journal ArticleDOI
Complete Genome Analysis of the C4 Subgenotype Strains of Enterovirus 71: Predominant Recombination C4 Viruses Persistently Circulating in China for 14 Years
Yan Zhang,Xiaojuan Tan,Aili Cui,Naiying Mao,Songtao Xu,Zhen Zhu,Jianhui Zhou,Jing Shi,Jing Shi,Yueping Zhao,Xianjun Wang,Xueyong Huang,Shuangli Zhu,Yong Zhang,Wei Tang,Hua Ling,Wenbo Xu +16 more
TL;DR: The comprehensive recombination analysis showed the evidence of genome recombination of subgenotype C4 (including C4a and C4b) sequences between structural genes from genotype C EV71 and non-structural genes from the prototype strains of CAV16, 14 and 4, but the evidenceOf intratypic recombination between C4 strains and B subgenotypes was not enough strong.