Z
Zhengpin Wang
Researcher at National Institutes of Health
Publications - 19
Citations - 930
Zhengpin Wang is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Folliculogenesis & Oocyte. The author has an hindex of 11, co-authored 16 publications receiving 628 citations. Previous affiliations of Zhengpin Wang include University of Minnesota & China Agricultural University.
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Journal ArticleDOI
scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells.
Zhengpin Wang,Xiaojiang Xu +1 more
TL;DR: Investigation of the expression pattern of ACE2 in adult human testes at the level of single-cell transcriptomes indicates that the human testis is a potential target of SARS-CoV-2 infection, which may have significant impact on understanding of the pathophysiology of this rapidly spreading disease.
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Transforming growth factor-β signaling participates in the maintenance of the primordial follicle pool in the mouse ovary.
Zhengpin Wang,Xinyi Mu,Meng Guo,Yijing Wang,Zhen Teng,Guan-Ping Mao,Wanbao Niu,Lizhao Feng,Lihua Zhao,Guoliang Xia +9 more
TL;DR: It is suggested that TGF-β signaling plays an important physiological role in the maintenance of the dormant pool of primordial follicles, which functions through activation of p70 S6 kinase 1 (S6K1)/ribosomal protein S6 (rpS6) signaling in mouse ovaries.
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Retinoic acid derived from the fetal ovary initiates meiosis in mouse germ cells
Xinyi Mu,Jing Wen,Meng Guo,Meng Guo,Jianwei Wang,Jianwei Wang,Ge Li,Zhengpin Wang,Yijing Wang,Zhen Teng,Yan Cui,Guoliang Xia +11 more
TL;DR: It is suggested that ovary‐derived RA is responsible for meiosis initiation, and exogenously supplied RA dose‐dependently reduced germ cell numbers in ovaries by accelerating the entry into meiosis.
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Cyclic AMP in oocytes controls meiotic prophase I and primordial folliculogenesis in the perinatal mouse ovary.
Yijing Wang,Zhen Teng,Ge Li,Xinyi Mu,Zhengpin Wang,Lizhao Feng,Wanbao Niu,Kun Huang,Xi Xiang,Chao Wang,Hua Zhang,Guoliang Xia +11 more
TL;DR: Evidence is provided that the level of cyclic AMP in oocytes regulates oocyte meiotic prophase I and primordial folliculogenesis in the perinatal mouse ovary and an in situ oocyte chromosome analysis approach is found that the dictyate arrest of oocytes is essential forPrimordial follicle formation under physiological conditions.
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FIGLA, LHX8 and SOHLH1 transcription factor networks regulate mouse oocyte growth and differentiation.
TL;DR: Findings substantiate a major role for FIGLA, LHX8 and SOHLH1 as multifunctional regulators of networks necessary for oocyte maintenance and differentiation during early folliculogenesis.