Z
Zhenzhong Cui
Researcher at Georgia Regents University
Publications - 11
Citations - 890
Zhenzhong Cui is an academic researcher from Georgia Regents University. The author has contributed to research in topics: NMDA receptor & Long-term potentiation. The author has an hindex of 8, co-authored 9 publications receiving 830 citations. Previous affiliations of Zhenzhong Cui include Princeton University & Boston University.
Papers
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Journal ArticleDOI
Genome-wide gene expression profiles of the developing mouse hippocampus
Monica Mody,Yanxiang Cao,Zhenzhong Cui,Khoon-Yen Tay,Andy Shyong,Eiji Shimizu,Kelvin Pham,Peter G. Schultz,Douglas Welsh,Joe Z. Tsien +9 more
TL;DR: The developmental molecular programs of the mouse hippocampus, a cortical structure critical for learning and memory, are analyzed by means of large-scale DNA microarray techniques andGene-cluster analysis was used to group these genes into 16 distinct clusters with striking patterns that appear to correlate with major developmental hallmarks and cellular events.
Journal ArticleDOI
Inducible and Reversible NR1 Knockout Reveals Crucial Role of the NMDA Receptor in Preserving Remote Memories in the Brain
TL;DR: A hitherto unrecognized role of the NMDA receptor in dynamically maintaining the long-term synaptic stability of memory storage circuits in the brain is revealed.
Journal ArticleDOI
Maintenance of superior learning and memory function in NR2B transgenic mice during ageing.
Xiaohua Cao,Zhenzhong Cui,Ruiben Feng,Ya-Ping Tang,Zhenxia Qin,Bing Mei,Bing Mei,Joe Z. Tsien,Joe Z. Tsien +8 more
TL;DR: It is concluded that increased expression of NR2B in the forebrain improves learning and memory function in the aged brain.
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Genetic enhancement of memory and long-term potentiation but not CA1 long-term depression in NR2B transgenic rats
Deheng Wang,Deheng Wang,Zhenzhong Cui,Qingwen Zeng,Hui Kuang,L. Phillip Wang,Joe Z. Tsien,Xiaohua Cao +7 more
TL;DR: The genetic experiments suggest that NR2B at CA1 synapses is not designated as a rate-limiting factor for the induction of long-term synaptic depression, but rather plays a crucial role in initiating the synaptic potentiation.
Journal ArticleDOI
Increased NR2A:NR2B ratio compresses long-term depression range and constrains long-term memory
Zhenzhong Cui,Ruiben Feng,Stephanie Jacobs,Yanhong Duan,Huimin Wang,Xiaohua Cao,Joe Z. Tsien +6 more
TL;DR: The results demonstrate that the increased NR2A:NR2B ratio is a critical genetic factor in constraining long-term memory in the adult brain and postulate that LTD-like process underlies post-learning information sculpting, a novel and essential consolidation step in transforming new information into long- term memory.