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Zhi-Sheng Jiang

Researcher at University of South China

Publications -  89
Citations -  2494

Zhi-Sheng Jiang is an academic researcher from University of South China. The author has contributed to research in topics: Inflammation & Endothelial stem cell. The author has an hindex of 25, co-authored 78 publications receiving 1850 citations. Previous affiliations of Zhi-Sheng Jiang include Sewanee: The University of the South & Libin Cardiovascular Institute of Alberta.

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Journal ArticleDOI

New role of PCSK9 in atherosclerotic inflammation promotion involving the TLR4/NF-κB pathway

Zhi-Han Tang, +10 more
- 29 Apr 2017 - 
TL;DR: PCSK9 gene interference could suppress atherosclerosis directly through decreasing vascular inflammation and inhibiting the TLR4/NF-κB signaling pathway without affecting plasma cholesterol level in high-fat diet-fed apoE KO mice.
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PCSK9 siRNA suppresses the inflammatory response induced by oxLDL through inhibition of NF-κB activation in THP-1-derived macrophages

Zhi-Han Tang, +8 more
- 01 Oct 2012 - 
TL;DR: It is suggested that PCSK9 may be used as a therapeutic target for the treatment of atherosclerosis since it suppresses oxLDL-induced IκB-α degradation and NF-κB nuclear translocation into THP-1-derived macrophages.
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PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax–caspase9–caspase3 pathway

Chun-Yan Wu, +5 more
- 01 Jan 2012 - 
TL;DR: It is suggested that ox-LDL-induced HUVECs apoptosis could be inhibited by PCSK9 siRNA, in which Bcl/Bax–caspase9– caspase3 pathway maybe was involved through reducing the Bcl-2-Bax ratio and inhibited the activation of both caspases9 and 3.
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Hydrogen sulfide, the next potent preventive and therapeutic agent in aging and age-associated diseases.

Yuan Zhang, +6 more
- 15 Mar 2013 - 
TL;DR: An overview of the physiological functions and effects of H2S in aging and age-associated diseases, and the potential health and therapeutic benefits of H 2S are provided.
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Macrophage polarization in atherosclerosis.

Sai Yang, +9 more
- 01 Feb 2020 - 
TL;DR: A new perspective for Atherosclerosis therapy is provided by summarizing the relationship between macrophage polarization and atherosclerosis, as well as treatment targeting macrophages polarization.