Z
Zhili Xu
Researcher at Nankai University
Publications - 3
Citations - 656
Zhili Xu is an academic researcher from Nankai University. The author has contributed to research in topics: Interleukin 3 & Wnt signaling pathway. The author has an hindex of 3, co-authored 3 publications receiving 593 citations.
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Journal ArticleDOI
Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model.
Ling Qiao,Zhili Xu,Tiejun Zhao,Zhigang Zhao,Mingxia Shi,Robert Chunhua Zhao,Lihong Ye,Xiaodong Zhang +7 more
TL;DR: It is demonstrated that hMSCs inhibit the malignant phenotypes of the H7402 and HepG2 human liver cancer cell lines, which include proliferation, colony-forming ability and oncogene expression both in vitro and in vivo.
Journal ArticleDOI
Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling.
TL;DR: The finding showed that beta-catenin was down-regulated in MCF-7 cells by conditioned media from Z3 hMSCs, and the expression level of dickkopf-1 (Dkk-1) was higher in Z3 cells than that inMCF- 7 cells, suggesting that DKK-1 secreted by Z3 Cells involves the inhibition via the Wnt pathway.
Journal ArticleDOI
Progressive Changes in Hepatoma Cells Stably Transfected with Hepatitis B Virus X Gene
TL;DR: Luciferase reporter gene analysis revealed that HBx induces the transcriptional activities of NF-ĸB and AP-1, which allows a better understanding of HBx function and the progressive changes during HBx-mediated hepatocarcinogenesis.