Z
Zhiqian Zhang
Researcher at Southern University of Science and Technology
Publications - 37
Citations - 1239
Zhiqian Zhang is an academic researcher from Southern University of Science and Technology. The author has contributed to research in topics: Carcinogenesis & Breast cancer. The author has an hindex of 17, co-authored 36 publications receiving 1006 citations. Previous affiliations of Zhiqian Zhang include Nankai University & Emory University.
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Journal ArticleDOI
Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells
Zhiqian Zhang,Baotong Zhang,Weidong Li,Liya Fu,Li Fu,Zhengmao Zhu,Jin-Tang Dong,Jin-Tang Dong +7 more
TL;DR: Results suggest that in malignant breast cancer cells, miR-203 is epigenetically silenced, and the silencing promotes tumor cell growth and invasion at least in part by upregulating the SNAI2 transcription factor.
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Both miR-17-5p and miR-20a Alleviate Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating STAT3 Expression
Miaomiao Zhang,Qiaofei Liu,Siping Mi,Xue Liang,Zhiqian Zhang,Xiaomin Su,Jinyi Liu,Yingying Chen,Mengmeng Wang,Yuan Zhang,Fenghua Guo,Zhujun Zhang,Rongcun Yang +12 more
TL;DR: The results suggest that miR-17-5p and mi-20a could potentially be used for immunotherapy against diseases, especially cancer, by blocking STAT3 expression.
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miR-223 suppresses differentiation of tumor-induced CD11b⁺ Gr1⁺ myeloid-derived suppressor cells from bone marrow cells.
Qiaofei Liu,Miaomiao Zhang,Xingran Jiang,Zhiqian Zhang,Lingyun Dai,Siping Min,Xilong Wu,Qingsheng He,Jingyi Liu,Yuan Zhang,Zhujun Zhang,Rongcun Yang +11 more
TL;DR: Interestingly, miR‐223 remarkably inhibits differentiation of BMCs into CD11b+Gr1+MDSCs in the presence of tumor‐associated factors by targeting myocyte enhancer factor 2C (MEF2C) and its targeting molecule MEF1C increases the number of MDSCs.
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KLF5 activates microRNA 200 transcription to maintain epithelial characteristics and prevent induced epithelial-mesenchymal transition in epithelial cells.
Baotong Zhang,Zhiqian Zhang,Zhiqian Zhang,Siyuan Xia,Changsheng Xing,Changsheng Xing,Xinpei Ci,Xin Li,Ranran Zhao,Sha Tian,Gui Ma,Zhengmao Zhu,Liya Fu,Jin-Tang Dong,Jin-Tang Dong +14 more
TL;DR: It is found that KLF5 maintains epithelial characteristics and prevents EMT by transcriptionally activating the miR-200 family in epithelial cells.
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miR-211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinoma
TL;DR: The results indicate that the long noncoding RNA MALAT1 could sponge miR‐211 as a competing endogenous RNA and potentially up‐regulate PHF19 expression, thus facilitating the OC progression.