Zhiwei Sun

TL;DR: A DSN-assisted dual-SERS biosensor for microRNA-10b in exosome and residual plasma of blood samples detection based on the Fe3O4 @Ag-DNA-Au@Ag@DTNB (SERS tag) conjugates and the recycling signal amplification.

TL;DR: The result provides a novel proposal to combine the perfect single-base recognition and signal-amplifying ability of the endonuclease DSN with cost-effective SERS strategy for miRNA point-of-care (POC) clinical diagnostics.

TL;DR: Based on the personalized SERS signal analysis, NSCLC patients can be distinguished from the healthy controls easily and the advantage of clearly individual quantification may help the doctor to discover the relationship of exosomal PD-L1 and the immnuotherapy responds in individual level.

TL;DR: The SERS strategy could be used to detect a broad range of bacteria by using different aptamers, moreover, the simple operation and precise quantification ability empower this assay great potential in the application of food safety and infectious disease point-of-care diagnosis.

TL;DR: The simple and inexpensive paper-based CRISPR-SERS strip has great potential for point-of-care testing (POCT) of nucleic acid targets especially in resource-poor or non-laboratory environments.