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Zhiyong Ma

Researcher at Wuhan University

Publications -  62
Citations -  3278

Zhiyong Ma is an academic researcher from Wuhan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 17, co-authored 32 publications receiving 2470 citations. Previous affiliations of Zhiyong Ma include Huazhong University of Science and Technology & University of Duisburg-Essen.

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Journal ArticleDOI

Characteristics of peripheral lymphocyte subset alteration in COVID-19 pneumonia

TL;DR: Peripheral lymphocyte subset alteration was associated with clinical characteristics and treatment efficacy of CO VID-19, and CD8+ T cells tended to be an independent predictor for COVID-19 severity andreatment efficacy.
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Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China.

TL;DR: Wang et al. as mentioned in this paper investigated the characteristics of patients with refractory CoV-2-infected pneumonia (COVID-19) and found that nearly 50% patients could not reach obvious clinical and radiological remission within 10 days after hospitalization.
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Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study.

TL;DR: Through a multivariate analysis of the causes of death in older patients, it was found that males, comorbidities, time from disease onset to hospitalization, abnormal kidney function, and elevated procalcitonin levels were all significantly associated with death.
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Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD-L1 blockade in chronic hepadnaviral infection.

TL;DR: In vivo blockade of PD-1/PD-L1 pathway on CD8 T cells, in combination with ETV treatment and DNA vaccination, potently enhanced the function of virus-specific T cells and led to sustained immunological control of viral infection, anti-WHs antibody development and complete viral clearance in some woodchucks.
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Modulation of hepatitis B virus replication and hepatocyte differentiation by MicroRNA-1†

TL;DR: These findings provide a novel perspective on the role of miRNAs in host‐virus interactions in HBV infection and reverse cancer cell phenotype, which is apparently beneficial for HBV replication.