D
Dieter Glebe
Researcher at University of Giessen
Publications - 130
Citations - 4702
Dieter Glebe is an academic researcher from University of Giessen. The author has contributed to research in topics: Hepatitis B virus & Hepatitis B. The author has an hindex of 31, co-authored 119 publications receiving 3727 citations. Previous affiliations of Dieter Glebe include Al-Quds University & Charité.
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Journal ArticleDOI
Update of the statements on biology and clinical impact of occult hepatitis B virus infection
Giovanni Raimondo,Stephen Locarnini,Teresa Pollicino,Massimo Levrero,Fabien Zoulim,Anna S. Lok,Jean-Pierre Allain,Thomas Berg,Antonio Bertoletti,Maurizia Rossana Brunetto,Raffaele Bruno,Ding-Shinn Chen,Nicola Coppola,Markus Cornberg,Antonio Craxì,Maura Dandri,Vito Di Marco,C. Ferrari,Giovanni Battista Gaeta,Dieter Glebe,Luca G. Guidotti,Anna Kramvis,Pietro Lampertico,Chengyao Li,Jake Liang,Alfredo Marzano,Thomas I. Michalak,Jean-Michel Pawlotsky,Daniele Prati,Massimo Puoti,Didier Samuel,Vincent Soriano,Giovanni Squadrito,Camille Sureau,Christian Trepo,Man-Fung Yuen +35 more
TL;DR: The objectives of the workshop were to review the existing knowledge on OBI, to identify issues that require further investigation, to highlight both the existing controversial and newly emerging aspects, and ultimately to update the statements previously agreed in 2008.
Journal ArticleDOI
Viral and cellular determinants involved in hepadnaviral entry
Dieter Glebe,Stephan Urban +1 more
TL;DR: Both HBV and DHBV in vitro infection systems will help to functionally dissect the hepadnaviral entry pathways, perform reverse genetics, improve current vaccines to combat acute and chronic infections of hepatitis B, and develop entry inhibitors for future clinical applications.
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Mapping of the Hepatitis B Virus Attachment Site by Use of Infection-Inhibiting preS1 Lipopeptides and Tupaia Hepatocytes
Dieter Glebe,Stephan Urban,Eva V. Knoop,Nilgün Cag,Peter Krass,Stefanie Grün,Aiste Bulavaite,Kestutis Sasnauskas,Wolfram H. Gerlich +8 more
TL;DR: Findings indicate that the current subunit hepatitis B vaccines may be improved by the addition of distinct preS1 epitopes, and preS 1 lipopeptides are promising candidates for specific antiviral therapy against hepatitis B infections.
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Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD-L1 blockade in chronic hepadnaviral infection.
Jia Liu,Ejuan Zhang,Zhiyong Ma,Weimin Wu,Anna D. Kosinska,Xiaoyong Zhang,Inga Möller,Pia L. Seiz,Dieter Glebe,Baoju Wang,Dongliang Yang,Mengji Lu,Michael Roggendorf +12 more
TL;DR: In vivo blockade of PD-1/PD-L1 pathway on CD8 T cells, in combination with ETV treatment and DNA vaccination, potently enhanced the function of virus-specific T cells and led to sustained immunological control of viral infection, anti-WHs antibody development and complete viral clearance in some woodchucks.
Journal ArticleDOI
Pre-s1 antigen-dependent infection of Tupaia hepatocyte cultures with human hepatitis B virus
Dieter Glebe,Mehriar Aliakbari,Peter Krass,Eva V. Knoop,Klaus Peter Valerius,Wolfram H. Gerlich +5 more
TL;DR: It is shown that purified HBV infects primary T. belangeri hepatocyte cultures in a very specific manner, as detected by HBV covalently closed circular DNA, mRNA, HBV e antigen, and HBsAg production.