Zhiyun Gong

TL;DR: A comprehensive and rigorous analysis of WGS data across multiple sample types suggests both Cas9 and Cpf1 nucleases are very specific in generating targeted DNA modifications and off-targeting can be avoided by designing guide RNAs with high specificity.

TL;DR: The presence of two distinct types of centromeres, coupled with the boom-and-bust cycles of centromeric satellite repeats in Solanum species, suggests that repeat-based centromere evolution can rapidly evolve from neocentromeres by de novo amplification and insertion of satellite repeat repeats in the CENH3 domains.

TL;DR: Cytological analyses show that chiasma frequency is reduced dramatically in mer3 mutants and the remaining chiasmata distribute randomly among different pollen mother cells, implying possible coexistence of two kinds of crossover in rice.

TL;DR: It is concluded that the CL34 repeat family emerged recently from the subtelomeric regions of potato chromosomes and is rapidly evolving, providing further evidence that subtelomersic domains are among the most dynamic regions in eukaryotic genomes.

TL;DR: OsSPO11-1 is essential for both homologous chromosomes pairing and crossover formation during meiosis in rice, implying that SC formation is disturbed severely.