Z
Zhongqiu Lu
Researcher at First Affiliated Hospital of Wenzhou Medical University
Publications - 160
Citations - 2878
Zhongqiu Lu is an academic researcher from First Affiliated Hospital of Wenzhou Medical University. The author has contributed to research in topics: Apoptosis & Sepsis. The author has an hindex of 27, co-authored 136 publications receiving 2114 citations. Previous affiliations of Zhongqiu Lu include Huazhong University of Science and Technology & Wenzhou Medical College.
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Journal ArticleDOI
Berberine alleviates cardiac ischemia/reperfusion injury by inhibiting excessive autophagy in cardiomyocytes.
Zhouqing Huang,Zhihua Han,Bozhi Ye,Zhenyu Dai,Peiren Shan,Zhongqiu Lu,Kezhi Dai,Changqian Wang,Weijian Huang +8 more
TL;DR: In this paper, the effects of berberine, a natural extract from Rhizoma coptidis, on the I/R-induced excessive autophagy in in vitro and in vivo models were investigated.
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Long Non-coding RNA Growth Arrest-specific Transcript 5 (GAS5) Inhibits Liver Fibrogenesis through a Mechanism of Competing Endogenous RNA
Fujun Yu,Jianjian Zheng,Yuqing Mao,Peihong Dong,Zhongqiu Lu,Guojun Li,Chuanyong Guo,Zhanju Liu,Xiaoming Fan +8 more
TL;DR: A new regulatory circuitry in liver fibrosis has been identified in which RNAs cross-talk by competing for shared microRNAs and GAS5 increased the level of p27 protein by functioning as a competing endogenous RNA for miR-222, thereby inhibiting the activation and proliferation of HSCs.
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MALAT1 functions as a competing endogenous RNA to mediate Rac1 expression by sequestering miR-101b in liver fibrosis.
TL;DR: It is uncovered that MALAT1 regulates Rac1 expression through miR-101b as a competing endogenous RNA (ceRNA), thereby influencing the proliferation, cell cycle and activation of primary HSCs.
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Incidence, risk factors and impact on outcomes of secondary infection in patients with septic shock: an 8-year retrospective study
Guangju Zhao,Dong Li,Qian Zhao,Jia-xing Song,Xiaorong Chen,Guangliang Hong,Mengfang Li,B Wu,Zhongqiu Lu +8 more
TL;DR: There was a statistically significant increased odds ratio for secondary infection in older patients and patients with a longer LOS in the intensive care unit (ICU), a higher Sequential Organ Failure Assessment (SOFA) score, and endotracheal intubation.
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SIRT1 exerts protective effects against paraquat-induced injury in mouse type II alveolar epithelial cells by deacetylating NRF2 in vitro.
Ding Yingwei,Guangju Zhao,Xiao-lin Li,Guangliang Hong,Mengfang Li,Qiao-meng Qiu,Bin Wu,Zhongqiu Lu +7 more
TL;DR: The findings of this study demonstrate that the protective effects of SIRT1 are associated with the activation of the NRF2/ARE antioxidant pathway in lung injury induced by PQ poisoning.