Z
Zhou-Hui Gu
Researcher at Chinese Academy of Sciences
Publications - 5
Citations - 681
Zhou-Hui Gu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Drug carrier & Serum albumin. The author has an hindex of 5, co-authored 5 publications receiving 651 citations.
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Journal ArticleDOI
PEGylated PLGA nanoparticles as protein carriers: synthesis, preparation and biodistribution in rats
Ya-Ping Li,Yuanying Pei,Xian-Ying Zhang,Zhou-Hui Gu,Zhao-Hui Zhou,Wei-Fang Yuan,Jian-Jun Zhou,Jianhua Zhu,Xiu-Jian Gao +8 more
TL;DR: PEGylated poly(lactic-co-glycolic acid) (PEG-PLGA) nanoparticles could be an effective carrier for PPD delivery and obviously change the protein biodistribution in rats compared with that of PLGA nanoparticles.
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PEGylated polycyanoacrylate nanoparticles as tumor necrosis factor-α carriers
Ya-Ping Li,Yuanying Pei,Zhao-Hui Zhou,Xian-Ying Zhang,Zhou-Hui Gu,Jian Ding,Jian-Jun Zhou,Xiu-Jian Gao +7 more
TL;DR: In this paper, the influence of solvent systems containing poly(methoxy-polyethyleneglycol cyanoacrylate-co-nhexadecyl cyano acrylate) (PEGylated PHDCA) on the biological activity of rHuTNF-alpha was investigated.
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Stealth Polycyanoacrylate Nanoparticles as Tumor Necrosis Factor-α Carriers: Pharmacokinetics and Anti-tumor Effects
Ya-Ping Li,Yuanying Pei,Zhao-Hui Zhou,Xian-Ying Zhang,Zhou-Hui Gu,Jian Ding,Jian-Jun Zhou,Xiu-Jian Gao,Jianhua Zhu +8 more
TL;DR: PEG-PHDCA nanoparticles loaded with rHuTNF-alpha showed higher antitumor potency at the same dose, which might be related to its higher accumulation in tumor tissues and longer plasma circulation time.
Journal Article
PEGylated recombinant human tumor necrosis factor alpha: preparation and anti-tumor potency.
TL;DR: PEG-modified rHuTNF-alpha could be more suitable for therapeutic use and had an increased anti-tumor potency compared with r HuT NF-alpha at a dose of 6000 IU per mouse.
Journal Article
PEGylated polycyanoacrylate nanoparticles as salvicine carriers: synthesis, preparation, and in vitro characterization
TL;DR: The results showed that the PEGylated PHDCA nanoparticles could be an effective carrier for salvicine delivery in the respect of anti-tumor potency.