Ziling Wang

TL;DR: Though substantial progress has been made in understanding the role of oxidative stress in IBD in humans and experimental animals, the underlying mechanisms are still not well defined and further studies are needed to validate how oxidative stress signaling is involved in and contributes to the development of IBD.

TL;DR: It is demonstrated that S100A4 promotes lung tumor development through inhibiting autophagy in a β-catenin signaling and S 100A4 receptor RAGE-dependent manner, which provides a novel mechanism of S100 a4-associated promotion of tumor development.

TL;DR: Ginsenoside Rg1 exerts the pharmacological effect of maintaining the activity of GSK-3β in Sca-1+ hematopoietic cells, enhances the antioxidant potential of cells, improves the redox homeostasis, and thus protects cells from the decline in differentiation ability caused by aging.

TL;DR: A novel function for Rg1 is uncovered that involves attenuating bone loss via Nrf2 antioxidant signaling, which in turn may potentially be utilized as a therapeutic agent for improving osteogenic differentiation in aging BMMSCs.

TL;DR: As a chalcone extracted from Alpinia rafflesiana, Cardamonin has been reported to serve as anticancer agent and induces autophagy and its effects were elucidated to elucidate the effects on 1 No.3 Shangyuancun, Haidian District, Beijing.