Z
Zivile Useckaite
Researcher at Trinity College, Dublin
Publications - 12
Citations - 175
Zivile Useckaite is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 5, co-authored 8 publications receiving 107 citations. Previous affiliations of Zivile Useckaite include Royal College of Surgeons in Ireland.
Papers
More filters
Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo
Mary Clare Cathcart,Zivile Useckaite,Clive Drakeford,Vikki Semik,Joanne Lysaght,Kathy Gately,Kenneth J. O'Byrne,Graham P. Pidgeon +7 more
TL;DR: This study is the first to demonstrate efficacy of baicalein both in-vitro and in-Vivo in NSCLC, and alterations in expression of VEGF, FGFR-2, and RB-1 have been implicated, suggesting a molecular mechanism underlying this in- vivo effect.
Journal ArticleDOI
Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo
Mary Clare Cathcart,Zivile Useckaite,Clive Drakeford,Vikki Semik,Joanne Lysaght,Kathy Gately,Kenneth J. O'Byrne,Graham P. Pidgeon +7 more
TL;DR: In this paper, the anti-tumour pathways activated following Baicalein treatment in non-small cell lung cancer (NSCLC) were examined both in-vitro and invivo.
Journal ArticleDOI
Selective Isolation of Liver-Derived Extracellular Vesicles Redefines Performance of miRNA Biomarkers for Non-Alcoholic Fatty Liver Disease
Lauren A. Newman,Zivile Useckaite,Jillian Johnson,Michael J. Sorich,Ashley M. Hopkins,Andrew Rowland +5 more
TL;DR: The capacity for liver-specific isolation to transform the performance of EV-derived miRNA biomarkers for NAFLD is demonstrated, robustly distinguishing patients with NAFL and NASH.
Journal ArticleDOI
BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer
Sarah Shields,Emer Conroy,Tony O'Grady,Alo McGoldrick,Kate Connor,Mark Ward,Zivile Useckaite,Eugene M. Dempsey,Rebecca Reilly,Yue Fan,Anthony J. Chubb,David Matallanas,Elaine W. Kay,Darran P. O'Connor,Amanda McCann,William M. Gallagher,Judith A. Coppinger,Judith A. Coppinger +17 more
TL;DR: A role for B AG3 in regulation of distinct EGFR modules is demonstrated and the potential of BAG3 as a therapeutic target in TNBC is highlighted.
Journal ArticleDOI
Increased extracellular vesicles mediate inflammatory signalling in cystic fibrosis
Zivile Useckaite,Mark Ward,Anne Trappe,Rebecca Reilly,Jenny Lennon,Holly Davage,David Matallanas,Hilary Cassidy,Eugene T. Dillon,Kiva Brennan,Sarah L. Doyle,S. Carter,Seamas C. Donnelly,Barry Linnane,Edward F. McKone,Paul McNally,Judith A. Coppinger +16 more
TL;DR: This study demonstrates that EVs are produced in CF airway cells, have differential protein expression at different ages and drive neutrophil recruitment in CF.