Z
Ziyu Jiang
Researcher at Nanjing University of Chinese Medicine
Publications - 26
Citations - 529
Ziyu Jiang is an academic researcher from Nanjing University of Chinese Medicine. The author has contributed to research in topics: Apoptosis & Autophagy. The author has an hindex of 10, co-authored 22 publications receiving 328 citations. Previous affiliations of Ziyu Jiang include Southeast University & Nanjing University.
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Journal ArticleDOI
Toxic effects of magnetic nanoparticles on normal cells and organs.
Ziyu Jiang,Kuizhong Shan,Jie Song,Jingbing Liu,Suresh Rajendran,Arivalagan Pugazhendhi,Joe Antony Jacob,Baoan Chen +7 more
TL;DR: Toxicity evaluation is a critical point in the development of nanoformulations and therefore, draws considerable attention and might be evaluated further for safety related issues considering future medications based on MNPs.
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Apoptosis induction by alantolactone in breast cancer MDA-MB-231 cells through reactive oxygen species-mediated mitochondrion-dependent pathway
Li Cui,Weiquan Bu,Jie Song,Liang Feng,Tingting Xu,Dan Liu,Wenbo Ding,Jianhua Wang,Changyang Li,Binge Ma,Yi Luo,Ziyu Jiang,Cheng-cheng Wang,Juan Chen,Jian Hou,Hong-mei Yan,Lei Yang,Xiao-Bin Jia +17 more
TL;DR: Findings suggested that alantolactone possessed anticancer activity via ROS-mediated mitochondrial dysfunction involving MAPK pathway, and had an effect on the transcription factors of NF-kB, AP-1 and STAT3.
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β-Elemene: Mechanistic Studies on Cancer Cell Interaction and Its Chemosensitization Effect.
TL;DR: In accordance to the evaluation made by the studies mentioned, apoptosis has been identified to be most possible reason behind anticancer activity exerted by β-elemene against a variety of cancer cell lines.
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Autophagy: An overview and its roles in cancer and obesity.
Joe Antony Jacob,Jumah Masoud Mohammad Salmani,Ziyu Jiang,Liang Feng,Jie Song,Xiao-Bin Jia,Baoan Chen +6 more
TL;DR: The markers, activators, inhibitors biological effects and roles of the three classes of autophagy in cancer and obesity are discussed.
Journal ArticleDOI
β-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1α/ATF6 pathway.
Ying Liu,Ziyu Jiang,Yuan-li Zhou,Huihui Qiu,Gang Wang,Yi Luo,Jingbing Liu,Xiong-wei Liu,Weiquan Bu,Jie Song,Li Cui,Xiao-Bin Jia,Liang Feng +12 more
TL;DR: The present in vivo and in vitro study revealed that the anti-NSCLC effect of β-elemene is closely related to the activation of ERs through PERK/IRE1α/ATF6 pathway, and this might be beneficial for clinical therapy of NSCLC.