Z
Zvi Selinger
Researcher at Hebrew University of Jerusalem
Publications - 142
Citations - 9240
Zvi Selinger is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Substance P & Receptor. The author has an hindex of 48, co-authored 142 publications receiving 9089 citations.
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Journal ArticleDOI
Linearization of the Bradford Protein Assay Increases Its Sensitivity: Theoretical and Experimental Studies
Tsaffrir Zor,Zvi Selinger +1 more
TL;DR: Under standard assay conditions, the ratio of the absorbances, 590 nm over 450 nm, is strictly linear with protein concentration, and a linear equation that perfectly fits the experimental data is provided on the basis of mass action and Beer's law.
Journal ArticleDOI
Mechanism of Adenylate Cyclase Activation by Cholera Toxin: Inhibition of GTP Hydrolysis at the Regulatory Site
Dan Cassel,Zvi Selinger +1 more
TL;DR: It is proposed that continuous GTP hydrolysis at the regulatory guanyl nucleotide site is an essential turn-off mechanism, terminating activation of the adenylate cyclase.
Journal ArticleDOI
Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes
Dan Cassel,Zvi Selinger +1 more
TL;DR: The following findings indicate that the catecholamine-stimulated GTPase is independent of the catalytic production of cyclic AMP by the adenylate cyclase.
Journal ArticleDOI
Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.
Journal ArticleDOI
Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP.
Dan Cassel,Zvi Selinger +1 more
TL;DR: The findings indicate that the inactive adenylate cyclase possesses tightly bound GDP, produced by the hydrolysis of GTP at the regulatory site, which the hormone stimulates by inducing an "opening" of the guanyl nucleotide site.