Bradley Hospital

About: Bradley Hospital is a healthcare organization based out in East Providence, Rhode Island, United States. It is known for research contribution in the topics: Mental health & Bipolar disorder. The organization has 261 authors who have published 265 publications receiving 10477 citations.

Acute sleep restriction effects on emotion responses in 30- to 36-month-old children

Abstract: Early childhood is a period of dramatic change in sleep and emotion processing, as well as a time when disturbance in both domains are first detected. Although sleep is recognized as central in emotion processing and psychopathology, the great majority of experimental data have been collected in adults. We examined the effects of acute sleep restriction (nap deprivation) on toddlers' emotion expression. Ten healthy children (seven females; 30-36 months old) followed a strict sleep schedule (≥12.5 h time in bed per 24-h) for 5 days, before each of two randomly assigned afternoon emotion assessments following Nap and No-Nap conditions (resulting in an 11-day protocol). Children viewed emotion-eliciting pictures (five positive, three neutral, three negative) and completed puzzles (one solvable, one unsolvable). Children's faces were video-recorded, and emotion displays were coded. When sleep restricted, children displayed less confusion in response to neutral pictures, more negativity to neutral and negative pictures, and less positivity to positive pictures. Sleep restriction also resulted in a 34% reduction in positive emotion responses (solvable puzzle), as well as a 31% increase in negative emotion responses and a 39% decrease in confused responses (unsolvable puzzle). These findings suggest sleep is a key factor in how young children respond to their world. When sleep restricted, toddlers are neither able to take full advantage of positive experiences nor are they as adaptive in challenging contexts. If insufficient sleep consistently 'taxes' young children's emotion responses, they may not manage emotion regulation challenges effectively, potentially placing them at risk for future emotional/behavioral problems.

Increased Sensitivity of the Circadian System to Light in Early/Mid-Puberty

Abstract: Context: Late adolescence is marked by a delay in sleep timing, which is partly driven by a delay shift of the circadian timing system. This study examined whether the sensitivity of the circadian system to light—the primary entraining stimulus to the circadian system—differs between pre- to mid-pubertal and late to postpubertal adolescents. Objective: The study was designed to determine the influence of puberty on the sensitivity of the circadian system to light in humans. Methods: Melatonin suppression to low and moderate light levels was assessed in 38 pre- to mid-pubertal (9.1–14.7 years) and 29 late to postpubertal (11.5–15.9 years) adolescents. They received 1 hour of four light levels on consecutive nights: approximately 0.1 (near-dark baseline condition), 15, 150, and 500 lux. One group received evening light beginning at 11:00 pm (n = 39); a second group received morning light beginning at 3:00 am (n = 28). Salivary melatonin was sampled every 30 minutes. Melatonin suppression for 15, 150, and 50...

Diagnostic Status and Symptomatic Behavior of Hard-to-Manage Preschool Children in Middle Childhood and Early Adolescence

Abstract: Followed 2 cohorts of hard-to-manage preschool children and comparison children without early problems to middle childhood and early adolescence. Children with early problems, especially problems that were still evident at school entry, were more likely to meet diagnostic criteria for an externalizing diagnosis at follow-up. Hard-to-manage children in Cohort 1 with problems that persisted from ages 3 through 9 years were much more likely to meet diagnostic criteria at age 13 than children whose early problems were less stable in elementary school. Similarly, hard-to-manage boys in Cohort 2 whose problems persisted at age 6 were more likely to meet criteria for an externalizing diagnosis at age 9 than hard-to-manage boys whose problems appeared less stable at age 6. Across cohorts, children with persistent problems had higher levels of symptoms and more varied symptoms at ages 3 and 4 and over the course of development.