Showing papers by "Chinese PLA General Hospital published in 1996"

Study of the Prevalence of Diabetes Mellitus in Adults in the Shougang Corporation in Beijing

Abstract: The aim was to determine the burden of diabetes mellitus (DM) in an urban area of China to aid us in planning preventive measures for those at risk of DM. A survey was conducted among the 29,859 subjects aged between 30 and 64 belonging to 32 units of the Shougang Corporation (a heavy industry enterprise) within the Beijing area. WHO study protocols and diagnostic criteria were used to determine the prevalence of DM and impaired glucose tolerance (IGT). The results showed that the age-adjusted prevalence of DM and impaired glucose tolerance (IGT) was 3.63% and 4.19%, respectively, both increasing with age. Peak prevalence for both occurred in the 60-64 age group. Prevalence showed no difference between the sexes in DM but was higher for females in IGT. Obesity, being overweight, a family history of diabetes mellitus and in women, a history of delivering babies with macrosomia, all correlated closely with the prevalence of DM and IGT. High protein intake was also associated with DM, Smoking had no effect on either DM or IGT. Intellectual workers had a higher incidence of IGT than manual workers. Seventy per cent DM was undiagnosed prior to the survey. This survey, done according to the recommendation of WHO, and including appropriate adjustments, reflects the growing prevalence of DM and IGT in this population. It can be compared with other studies for epidemiological analysis.

[Effect of total flavonoids of radix Astragali on free radical production by myocardial ischemia-reperfusion in rats].

Abstract: Observation was made on the effect of TFA on FR produced by ischemia-reperfusion in two groups of Langendorff hearts of rats. The result showed that oxygen free radicals were reduced by TFA in myocardial ischemia-reperfusion in rats.

[US-guided microwave in the treatment of liver cancer: experimental study and preliminary clinical application].

Abstract: OBJECTIVE To completely coagulate deep tumor and protect normal tissue by using microwave electrode is vivo and in vitro animal experimental study, under US-guided percutaneous microwave coagulation. METHOD The Ultrasound Microwave Therapy-I (UMT-I) equipment was utilized at 2450 MHz in frequency. RESULTS Microwave coagulation could produce a stable necrosis area of 2cm in diameter with irradiation at 60-80W for 60-180 seconds, and the corresponding temperature at its surrounding area was 61.95 +/- 5.81 degrees C. Microwave induced coagulation of tumor correlated well with the sonographic changes. The shape of coagulated area was elliptic when 27 mm or 9 mm of the inner conductor of electrode was exposed, and the temperature of the shaft of the electrode raised smaller and slowly based on our animal experimental study, 15 nodules of 12 patients with liver cancer were microwave-coagulated under US-guide. The temperature of tumor surrounding area raised to 54-69.5 degrees C during operation. After treatment, all lesions had smaller size, hypoechogenicity and disappearance of blood flow. AFP titer dropped in 7 patients and normalized in 4. CONCLUSION US-guided microwave for the treatment of liver cancer is effective in coagulating deep tumor and protecting normal tissue.

[Effects of insulin and captopril on growth of glomerular mesangial cells in STZ-induced diabetic rats].

Abstract: OBJECTIVE To observe the effects of insulin and captopril on growth of mesangial cells and on production of interleukin-6 (IL-6) and tumor necrosis factor (TNF) in culture media of glomerular cells. METHOD Streptozocin induced diabetic rats (DM rats) were compared with normal wistar rats. RESULTS The CPM value of 3H-TdR incorporated into mesangial cells in DM rats was significantly higher than that in Wistar rats. When the culture media was added by 5 x 10(-4) U/ml, 5 x 10(-3) U/ml and 5 x 10(-1) U/ml of insulin, the CPM value incorporated into mesangial cells and the concentration of IL-6 in the culture media of both DM and wistar rats were significantly higher than those of the control (no insulin). When captopril (10(-6) mol/L, 10(-4) mol/L, 10(-3) mol/L) was added into the media in different concentration, the cpm value of 3H-TdR and the concentration of TNF in DM rats were significantly lower than those of the control (no captopril). But the CPM value of 3H-TdR in Wistar rats was lower than that in the control, which was only seen in the concentration of 10(-3)M captopril. CONCLUSION Ins could promote 3H-TdR in corporation and increase the production of IL-6, and captopril inhibited 3H-TdR in corporation and decrease the production of TNF.

Study of relationship between the bacteria in air and the clinic infection

Abstract: The Source of infectious bacteria is the first problem in provension of infection considered by the medical workers. In this paper, with the method of bacteria plasmid analysis, chromosome DNA restriction fragment length polymorphism analysis, drug resistance experiment (antibacterial drug, sterilizing drug) and so on. We confirmed that staphylococci of nosocomi is mainly from air; but the gram-negative bacteria is mainly from the patient's pharyngeal portion; and cause hospital infection indirectly. The drug resistance of gram-negative from air was lower than the same gram-negative bacilli's isolated from the patient. Moreover, kill bacteria the infectious strain is same strain in air. Above-mentioed results provided the important basis for control of the hoslpital infection.