Crawford University

About: Crawford University is a education organization based out in Lagos, Nigeria. It is known for research contribution in the topics: Ascorbic acid & Government. The organization has 79 authors who have published 86 publications receiving 279 citations.

Potential Anti-Cancer Flavonoids Isolated From Caesalpinia bonduc Young Twigs and Leaves: Molecular Docking and In Silico Studies

Abstract: Tyrosine kinase (TK), vascular endothelial growth factor (VEGF), and matrix metalloproteinases (MMP) are important cancer therapeutic target proteins. Based on reported anti-cancer and cytotoxic ac...

The Abundance and Biting Patterns of Culex quinquefasciatus Say (Culicidae) in the Coastal Region of Nigeria

Abstract: This study was aimed at determining the abundance and biting patterns of Culex quinquefasciatus in the coastal region of Nigeria. Collections were done by human landing catch and by CDC miniature light traps from September 2005 to August 2006. A total of 3798 C. quinquefasciatus females were collected. The highest number of females was caught in the month of August and it represented nearly a quarter (24.0%) of the total females collected. In all, 38.8% of females dissected were parous. The abundance of C. quinquefasciatus followed the pattern of rainfall with the population starting to expand at the onset of the rains. The highest increase was found after the temperature had peaked. The mean of biting was 3.2 times more in the rainy season than in the dry season, whereas the transmission potential was higher in the dry season. C. quinquefasciatus is presently regarded as a biting nuisance having no significant epidemiological importance yet. Efforts at its control should be intensified before it is too late.

Biochemical Characterisation of the Leaf of Morinda Lucida: Prospects for Environmentally‐Friendly Steel‐Rebar Corrosion‐Protection in Aggressive Medium

Abstract: This paper employs atomic absorption spectroscopy (AAS), Fourier transform infrared spectroscopy (FTIR) and phytochemical screening methods for biochemical characterisation of the inorganic and organic constituents of the leaf of Morinda lucida. AAS results showed that this well-known medicinal-plant is high in iron (Fe = 5143.54 µg/g), low in cadmium (Cd = 2.9506 µg/g) and does not contain chromium (Cr). Also, Euclidean hit-list from the FT-IR instrument suggests Morinda lucida leaf-extract contains S-, N-, Br- and O- containing heteroatoms. The phytochemical analyses indicated presence of tannins, phlobatannins, saponins, flavonoids and terpenoids. These results bare prospects on suitability of leaf-extract from Morinda lucida for environmentally-friendly steel-rebar corrosion-protection in aggressive medium. Preliminary tests based on this showed that use of 0.083 wt% cement of Morinda lucida retarded steel-rebar total-corrosion and eventually reduced corrosion rate as admixture in duplicated 3.5% NaCl-immersed concretes, relative to control samples in the same medium.