Showing papers by "Israel Ministry of Health published in 1980"
TL;DR: A comparative study of adverse drug reactions (ADR) leading to hospital admission showed that 103 out of 2499 medical admissions in Jerusalem and 167 out of 2933 admissions in Berlin were due to such reactions.
Abstract: A comparative study of adverse drug reactions (ADR) leading to hospital admission showed that 103 (4.1%) out of 2499 medical admissions in Jerusalem and 167 (5.7%) out of 2933 admissions in Berlin were due to such reactions. Sex distribution in the two patient — populations was almost equal but the Jerusalem patients were younger. The most frequent ADRs were digitalis intoxication (in Berlin) and reactions to antibiotics (in Jerusalem). Other important differences were noted in the relative frequencies of ADRs associated anticoagulants, hypoglycemic agents and oral contraceptives. They were probably related to differences in drug usage in the two countries. The most common major side effects were arrhythmias, allergic reactions, bleeding, congestive heart failure, bronchospasm and hypoglycemia. The following risk factors were identified in both cities: old age, female sex, impaired renal function, previous history of ADR and polypragmasia.
100 citations
TL;DR: Varicella-zoster virions (VZV) were isolated from cytoplasm of VZV-infected human fibroblasts by zone centrifugation in glycerol gradients followed by two cycles of equilibrium flotation on Glycerol-tartrate gradients.
34 citations
TL;DR: Until universally accepted, standardized procedures for the assessment of lymphocyte functions in vitro become available, each laboratory should establish the changes induced by cryopreservation in lymphocyte function with the methods employed locally to allow the observations made oncryopreserved lymphocytes to be meaningful.
26 citations
TL;DR: Nucleic acid hybridization assays showed no sequence homology between the genome of P3HR‐I virus and avian myeloblastosis virus, murine oncornaviruses, simian sarcoma virus or RD114 virus.
Abstract: Burkitt's lymphoma cell line, P3HR-1, was found to secrete virions with properties of known type-C RNA tumor viruses. The viral particles had a buoyant density of 1.16 g/ml in sucrose gradients and contained a highmolecular-weight RNA and an RNA-instructed DMA polymerase. The viral polymerase was active in an endogenous reaction requiring the presence of the four deoxyriboside triphosphates and manganese ions, and was sensitive to RNase. The DNA product of the endogenous reaction specifically hybridized to P3HR-I viral 60 to 70S RNA. Electron microscopic examination of ultrathin sections of P3HR-I cells revealed immature, mature and budding virions typical of type-C retroviridae. Nucleic acid hybridization assays showed no sequence homology between the genome of P3HR-I virus and avian myeloblastosis virus, murine oncornaviruses, simian sarcoma virus or RD114 virus.
16 citations
TL;DR: In stages II, III and IV, immigrants of Western origin survived significantly longer than native-born Israeli women and immigrants from other Asian or North African countries, suggesting that the different disease patterns may be distributed unequally among the several population groups, favoring women ofWestern origin.
15 citations
TL;DR: A simple protocol for freezing the promastigote vaccine in liquid nitrogen is described, which allows prolonged storage of the material in the final container and tests of biochemical identity, sterility, pyrogenicity and infectivity for animals and cultured cells are carried out.
11 citations
TL;DR: The activities of eight enzymes were determined in the regenerating liver of rats after partial hepatectomy and a progressive statistically significant increase in activities was obtained on days 10 and 20 of regeneration.
Abstract: The activities of eight enzymes were determined in the regenerating liver of rats after partial hepatectomy. For five enzymes, i.e., aldolase, lactate dehydrogenase, alanine transaminase, 5-nucleotidase, and acid phosphatase a progressive statistically significant increase in activities was obtained on days 10 and 20 of regeneration. This increase was not at the high level observed for parallel activities in fetal liver of rats on the 20th day of gestation. A possible interpretation of the process of liver regeneration is suggested.
6 citations
TL;DR: It is suggested that the increased incidence of less advanced cancers was caused by more self-examination by women which, in turn, resulted from increased public awareness of cancer, reinforced by specific screening and education programs.
1 citations
TL;DR: Low Apgar score was much more frequent in infants delivered by vacuum extraction than in those delivered spontaneously, with forceps or by cesarian section, and was higher when fetal distress occurred.