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Showing papers by "University of Gothenburg published in 1970"


Journal ArticleDOI
TL;DR: A review is given of the literature on methods available for improving retention of dental prostheses by implantation of anchoring devices in the jaws including a variety of anamnestic interpretations and complications.
Abstract: A review is given of the literature on methods available for improving retention of dental prostheses by implantation of anchoring devices in the jaws. Different aspects of the problem concerning m...

533 citations



Journal ArticleDOI
TL;DR: The hypothesis based on previous evidences that the main circulatory changes in physical training occur in the circulation of the skeletal muscle is supported.
Abstract: Six weeks' physical training of seven healthy subjects was followed by a mean decrease of exercise muscle blood flow (ml./100 g/min) from 32·7 to 22·6 and an increase of succinic dehydrogenase activity ( V O2 μl./g/min) from 33·0 to 47·4 in vastus lateralis muscle. Estimated maximal aerobic power ( V O2 max.) increased by 30%. These results support the hypothesis based on previous evidences that the main circulatory changes in physical training occur in the circulation of the skeletal muscle.

101 citations


Journal ArticleDOI
TL;DR: The investigation suggests that in girls the range of movement of the mandible has reached adult level by 10 years, and the opening capacity in children was found to be positively correlated with body height and body weight.
Abstract: — The range of movement of the mandible was studied in 103 boys and girls aged 7 years, in 110 boys and girls aged 10 years, and in 60 women aged 20 years. The mobility of the mandible was estimated by repeated direct measurement of the maximal opening capacity, and in the 10-year-old children and the women also by measurement of maximal protrusion and lateral movement. The method for recording the mobility of the mandible proved to be precise. Lateral movement of the mandible to the right was greater than to the left both in children and adults. No difference in opening capacity or maximal protrusion was found between the boys and the girls, while lateral movement was somewhat larger in the boys. The mean maximal opening capacity was 46 mm in the 7-year-old children, 51 mm in the 10-year-old children, and 51 mm in the adult women. Maximal protrusion and lateral movement was, on the average, 9–10 mm in the 10-year-old children and in the adult women. The investigation suggests that in girls the range of movement of the mandible has reached adult level by 10 years. The opening capacity in children was found to be positively correlated with body height and body weight. Both in children and adults relatively high positive correlations were found between opening capacity, protrusion, and lateral movement.

91 citations



Journal ArticleDOI
TL;DR: The flow conductivity of rabbit and human sclera as a function of hydration was measured and the fraction of the total aqueous humor drainage via the sClera is then 18% in the rabbit and 21% in man.

63 citations


Journal ArticleDOI
01 Aug 1970
TL;DR: In this article, the authors evaluated the radiation treatment of painful conditions of the Locomotor System (LOS) in a double blind study and concluded that the treatment was effective.
Abstract: (1970). Evaluation of Radiation Treatment of Painful Conditions of the Locomotor System: A Double Blind Study. Acta Radiologica: Therapy, Physics, Biology: Vol. 9, No. 4, pp. 311-322.

57 citations


Journal ArticleDOI
TL;DR: It is concluded that in the dog it is passible through topical applications of chlorhexidine to establish and maintain a plaque- and gingivitis-free dentition.
Abstract: — The present study examines the effect of topically applied chlorhexidine gluconate on chronically inflamed gingiva and standardized gingival wounds. Five beagle dogs were fed a soft “gingivitis inducing” diet for a period of 5 months. Subsequently, a 2 % chlorhexidine solution was applied daily for 42 days to the left molars, premolars, and canines of three dogs, the corresponding teeth in the right quadrants serving as controls. The degree of gingivitis, plaque, gingival exudation, and number of crevicular leukocytes were assessed on days 0, 11, 28, 35, and 42. The healing after gingival biopsy was studied in two dogs using the same parameters on days 0, 4, 7, 14, 28, and 42. In one of the dogs chlorhexidine was applied daily to the teeth and gingiva; the other dog had saline treatment. Biopsies for histologic examination were obtained at the beginning and the end of the experiment. From these criteria, it was shown that one daily topical application of 2 % chlorhexidine gluconate to the teeth and gingiva of the dog removes plaque and resolbes a well-established chronic gingivitis. It is concluded that in the dog it is passible through topical applications of chlorhexidine to establish and maintain a plaque- and gingivitis-free dentition.

53 citations


Journal ArticleDOI
TL;DR: Observations indicate that chlorhexidine gluconate does not penetrate the undamaged oral epithelium and induces an increase in non-enzymic formazan deposition in the surface layers.
Abstract: The effects of local applications of a 2.2 mM (0.2 per cent) chlorhexidine gluconate solution on the oral mucous membranes have been evaluated by vital microscopy and histological and enzyme histochemical methods. Chlorhexidine gluconate applied onto intact or dekeratinized hamster cheek-pouch did not induce microvascular disturbances in the underlying connective tissue. On a defective cheek-pouch surface, however, the test solution caused hemolysis, intravascular granulo-cytosis and thrombus formation. These observations indicate that chlorhexidine gluconate does not penetrate the undamaged oral epithelium. Daily application of 2.2 mM chlorhexidine gluconate on the palatal or sublingual mucosa did not induce reactions in the underlying connective tissue. The application of the test solution onto the oral epithelium, however, induced an increase in non-enzymic formazan deposition in the surface layers. These staining reactions, which developed rapidly, did not appear to increase during prolonged administration.

50 citations


Journal ArticleDOI
TL;DR: In this paper, an apparatus for desalting sea water by electrodialysis with ion exchange membranes is described, and the desalted samples are evaporated in vacua and investigated by liquid-liquid and gas-liquid Chromatographic methods.

48 citations


01 Jan 1970
TL;DR: The authors used nationally representative panel data to analyse the relationship between income diversification and incomes for Zambian smallholder households and found that shifting to a higher degree of diversification is generally associated with higher incomes.
Abstract: This paper uses nationally representative panel data to analyse the relationship between income diversification and incomes for Zambian smallholder households. We show that shifting to a higher degree of diversification is generally associated with higher incomes. We find that diversification is driven by endowments and access to markets and finance. Education opens up opportunities for well-paid non-agricultural activities, while land shortage forces distress diversification into agricultural wage work.

Journal ArticleDOI
TL;DR: It is demonstrated that a monoamine is localized to the granules, which in all probability also contain a polypeptide hormone.

Journal ArticleDOI
TL;DR: In an experimental series in dogs large mandibular and tibial defects were reconstructed by using a titanium splint to re-establish skeletal continuity and autologous grafts of spongious bone and marrow compensating for the bone removed.
Abstract: In an experimental series in dogs large mandibular and tibial defects were reconstructed by using a titanium splint to re-establish skeletal continuity and autologous grafts of spongious bone and marrow compensating for the bone removed. The results of this experimental investigation were used to design a method for repair of mandibular defects in man. With the aid of titanium splints and autologous bone and marrow grafts the anatomy of the mandible could be restituted and immediate function achieved. The results of application of these principles for repair of mandibular defects in 10 cases are reported.


Journal ArticleDOI
TL;DR: Lysyl transfer ribonucleic acid synthetase purified from yeast to apparent homogeneity has been obtained in a crystalline form amenable to x-ray crystallographic study.

Journal ArticleDOI
TL;DR: It is concluded that the decrease in the cerebral perfusion pressure gave rise to a longlasting disturbance of the oxidative metabolism, possible due to reversible structural tissue damage.
Abstract: In order to study effects of increased cerebrospinal fluid pressure upon brain tissue concentrations of bicarbonate, lactate, pyruvate, ATP, ADP, AMP and phosphocreatine, the metabolites were measured in cortical tissue of 37 dogs frozen in situ during and after a 15 min decrease of the cerebral perfusion pressure to 30–35 mm Hg, induced by connecting the cisterna magna to a reservoir with artificial CSF. The intracranial hypertension was found to give a variable but marked increase in tissue lactate and pyruvate, and in the lactate/pyruvate ratio, as well as a corresponding decrease in the bicarbonate concentration. Marked decreases in the ATP and phosphocreatine concentrations were also seen. Resting values for these metabolites were not approached until 30–90 min after restitution of normal perfusion pressure. Since the changes in ATP and phosphocreatine corresponded in time to the changes in the lactate, pyruvate and bicarbonate concentrations it is concluded that the decrease in the cerebral perfusion pressure gave rise to a longlasting disturbance of the oxidative metabolism, possible due to reversible structural tissue damage. Cerebral blood flow measured in 10 of the dogs showed varying decreases of cerebral blood flow during the intracranial hypertension period. Usually, hyperemia of 30–90 min duration followed when the CSF pressure was released. The hyperemia and the metabolic changes were of approximately the same duration.

Journal ArticleDOI
TL;DR: In this article, the effect of local Corticosteroid treatment on Rheumatoid Knee Joints was investigated and the results showed that local corticosteroids significantly reduced the synovial pH of the knee joint.
Abstract: (1970). Synovial pH in Rheumatoid Knee Joints: II. The Effect of Local Corticosteroid Treatment. Acta Orthopaedica Scandinavica: Vol. 41, No. 3, pp. 354-362.

Book ChapterDOI
01 Jan 1970
TL;DR: D dosage regimens, which would maintain therapeutically optimal plasma drug levels during long-term treatment, were suggested by a pharmacokinetic model of the distribution and elimination of acetazolamide.
Abstract: The relation between plasma concentrations and effects on eye pressure was studied in patients with glaucoma after oral and parenteral administration of acetazolamide. A minimum effective plasma concentration, 10 μg/ml, was defined. By use of this concentration and calculated rates of absorption, elimination and apparent volume of distribution, dosage regimens, which would maintain therapeutically optimal plasma drug levels during long-term treatment, were suggested. A pharmacokinetic model of the distribution and elimination of acetazolamide was established, and discussed in relation to this drugs' action as an inhibitor of carbonic anhydrase.

Journal ArticleDOI
TL;DR: In this paper, the time of flight spectra have been fitted by a least squares technique to yield relative excitation probabilities of absolute differential cross sections for the transitions n = 0 → n = 1, n =0 → n=1, n= 0→ n = 2 up to n = ≥ 9.73.

Journal ArticleDOI
TL;DR: Growing oocytes of the marine crab Cancer pagurus L. contain different kinds of yolk inclusions that presumably are lipids and the lipid character of these granules was demonstrated by extracting them from the epon-embedded ultrathin sections by using the method of Mayor et al.
Abstract: Growing oocytes of the marine crab Cancer pagurus L. contain different kinds of yolk inclusions. Some of them are strongly blackened by OsO4 and presumably are lipids. The lipid character of these granules was demonstrated by extracting them from the epon-embedded ultrathin sections by using the method of Mayor et al. (J. Biophys. Biochem. Cytol., 9:909, 1961) originally recommended for the removal of epoxy resin from sections intended for light microscopy. This technique was also applied to liver tissue of mouse with successful result.

Journal ArticleDOI
TL;DR: When tissue fragments were incubated in Parker medium 199 enlargement of human fat cells was associated with increasing rates of glucose incorporation into the lipids and of glycerol release, but the sensitivity to insulin, expressed as percentage change above basal values, showed a negative correlation to cell size.

Journal ArticleDOI
TL;DR: Human and rabbit corneal stroma have about the same flow conductivity in the hydration range of 2·5–5·0 g water per g dry tissue.

Journal ArticleDOI
TL;DR: It is proposed that thymine 7-hydroxylase belongs to the class of oxygenases which utilize a 2-keto acid for O2 reduction, and a stoichiometric relationship was found between hydroxylation of thymine and decarboxylating of2-ketoglutarate.

Journal ArticleDOI
TL;DR: In this paper, it was shown that formate, acetate, propionate and n-butyrate buffers interfere with the precipitation reaction and the carboxylates cause the lanthanum fluoride membrane electrode to work sluggishly after the titration.

Journal ArticleDOI
TL;DR: In this article, the curcumin method of Uppstrom for the determination of boron in sea water has been adapted to an open system for automatic analysis and the equipment used is a module system called Autolab.

Journal ArticleDOI
TL;DR: The results of the investigation indicate that the range of movement of the mandible is small in Persons with a rectangular face while it is large in persons with a triangular face with the temporo-mandibular joints situated far posteriorly.
Abstract: — Maximal opening capacity of the mouth, maximal protrusion, and lateral movement of the mandible were correlated with the morphology of the face as seen in profile radiographs. The material consisted of 56 boys and 53 girls aged 10 years 4 months on the average. The results of the investigation indicate that the range of movement of the mandible is small in persons with a rectangular face while it is large in persons with a triangular face with the temporo-mandibular joints situated far posteriorly. The calculation of multiple correlation coefficients showed that one-fourth to one-half of the interindividual variations in range of movement can be explained by differences between facial types. The opening capacity and lateral movement of the mandible varied conspicuously with facial morphology as did mandibular protrusion, though somewhat less.

Journal ArticleDOI
TL;DR: The purpose of the present investigation was to study the lipolysis in human fat cells of different sizes with or without the addition of glucose or insulin to the incubation medium.

Journal ArticleDOI
TL;DR: In this paper, the axial field distribution of suitable external magnets is shown in Fig. 2 and directional control at bifurcations is with a hand-held AlNiCo 5 cylindrical magnet held at the chest.
Abstract: ~. ~. \ in the usual way from the proximal end. Directional control at bifurcations is with a hand-held AlNiCo 5 cylindrical magnet held at the chest. The axial field distribution of suitable external magnets is shown in Fig. 2.

Journal ArticleDOI
TL;DR: The hypothesis that Toxoplasma gondii is capable of synthesizing an enzyme-like factor, reacting with the host cell surface, and, thereby, facilitating the penetration of the parasites is supported.
Abstract: The host cell penetration of Toxoplasma gondii was studied with reference to synthesis of a penetration-enhancing factor and the penetrative capacity of the parasites during the various phases of the infectious cycle. HeLa cells as suspension or monolayer cultures were infected with Toxoplasma. After a lag phase shorter than 1 hr, there was a synthesis of penetration-enhancing factor demonstrable in the parasites. Exposure of the factor to host cells resulted in disappearance of its penetration-enhancing activity. The findings were in accord with the hypothesis that Toxoplasma gondii is capable of synthesizing an enzyme-like factor, reacting with the host cell surface, and, thereby, facilitating the penetration of the parasites. This hypothesis was further supported by the observations that the penetrative capacity of extracellular parasites gradually was reduced in presence of host cells and that intracellular parasites released artificially from host cells shortly after penetration were found to have a reduced penetrative capacity. Parasites allowed to remain for 4 hr or more intracellularly could restore and markedly improve their penetrative capacity.