scispace - formally typeset
Search or ask a question
Institution

Zhongnan Hospital of Wuhan University

Healthcare
About: Zhongnan Hospital of Wuhan University is a healthcare organization based out in . It is known for research contribution in the topics: Medicine & Chemistry. The organization has 57 authors who have published 112 publications receiving 340 citations.
Topics: Medicine, Chemistry, Internal medicine, Biology, Gene

Papers published on a yearly basis

Papers
More filters
Journal ArticleDOI
TL;DR: In this article , a high average ZT value of ∼1.13 was achieved in n-type PbSe −18%SnS −0.5%Cu at 300-873 K through the rational optimization of carrier mobility.
Abstract: Carrier mobility is a key parameter for thermoelectric performance. A high average ZT value of ∼1.13 can be achieved in n-type PbSe–18%SnS–0.5%Cu at 300–873 K through the rational optimization of carrier mobility.

27 citations

Journal ArticleDOI
TL;DR: An alternative strategy of choosing photothermal and weak-immunostimulatory porous silicon@Au nanocomposites as particulate cores to prepare a biomimetic nanovaccine is reported to improve its biosafety and immunotherapeutic efficacy for solid tumors as discussed by the authors .
Abstract: An alternative strategy of choosing photothermal and weak-immunostimulatory porous silicon@Au nanocomposites as particulate cores to prepare a biomimetic nanovaccine is reported to improve its biosafety and immunotherapeutic efficacy for solid tumors. A quantitative analysis method is used to calculate the loading amount of cancer cell membranes onto porous silicon@Au nanocomposites. Assisted with foreign-body responses, these exogenous nanoparticulate cores with weak immunostimulatory effect can still efficiently deliver cancer cell membranes into dendritic cells to activate them and the downstream antitumor immunity, resulting in no occurrence of solid tumors and the survival of all immunized mice during 55 day observation. In addition, this nanovaccine, as a photothermal therapeutic agent, synergized with additional immunotherapies can significantly inhibit the growth and metastasis of established solid tumors, via the initiation of the antitumor immune responses in the body and the reversion of their immunosuppressive microenvironments. Considering the versatile surface engineering of porous silicon nanoparticles, the strategy developed here is beneficial to construct multifunctional nanovaccines with better biosafety and more diagnosis or therapeutic modalities against the occurrence, recurrence, or metastasis of solid tumors in future clinical practice.

20 citations

Journal ArticleDOI
TL;DR: In this paper, a novel multifunctional β-cyclodextrin microporous organic network (CD-MON) has been successfully synthesized and used to remove bisphenol A (BPA) from water.

14 citations

Journal ArticleDOI
TL;DR: In this article, a novel and simple in vitro evaluation method for human skin exposure to parabens was established for the first time using magnetic porous carbon (MPC) derived from discarded cigarette butts as an adsorbent of magnetic solid phase extraction (MSPE).

14 citations

Journal ArticleDOI
TL;DR: In this article , a novel and simple in vitro evaluation method for human skin exposure to parabens was established for the first time, where magnetic porous carbon (MPC) derived from discarded cigarette butts was prepared as an adsorbent of magnetic solid phase extraction (MSPE).

14 citations


Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202325
202285
20213
20201
20121