•Journal•ISSN: 1551-7004
Arkivoc
ARKAT USA, Inc.
About: Arkivoc is an academic journal published by ARKAT USA, Inc.. The journal publishes majorly in the area(s): Catalysis & Aryl. It has an ISSN identifier of 1551-7004. It is also open access. Over the lifetime, 4204 publications have been published receiving 36983 citations. The journal is also known as: A R K I V O C & ARKIVOC : free online journal of organic chemistry.
Topics: Catalysis, Aryl, Chemistry, Ring (chemistry), Cycloaddition
Papers published on a yearly basis
Papers
More filters
TL;DR: The potential of exciting research activity in the chemistry of furfural derived compounds is reallymassive, it is no wonder that research in this area, starting at the end of 19th century, is still being developed Numerous important scientific groups are carrying out studies on the synthesis, and applications of HMF and its derivatives as discussed by the authors.
Abstract: The prospect of exciting research activity in the chemistry of furfural derived compounds such as
5-hydroxymethylfurfural (HMF), 2,5-furandicarbaldehyde and 2,5-furan-dicarboxylic acid
prompted the writing of this article As the field of application of these compounds is really
enormous, it is no wonder that research in this area, starting at the end of 19th century, is still
being developed Numerous important scientific groups are carrying out studies on the synthesis,
and applications of HMF and its derivatives Notable among these are, Gaset (Toulouse),
Descotes (Lyon), Lichtenthaler (Darmstadt), and Gelas (Clermont-Ferrand) Not only academic
scientists are interested in this subject, the chemical industry, is represented by sugar companies
such as Beghin-Say, and Suddeutsche Zucker Despite this interest, there are not many
comprehensive monographs or reviews covering the chemistry of HMF Two classic reviews, by
Newth and by Feather and Harris, appeared in 1951 and 1973 respectively Reviews by Gaset
et al,3 Faury et al and by Kuster are more recent, but they are not detailed An important
review review by Cottier and Descotes6 appeared in 1991
This review is written to update those above, to summarize the contributions of the last 100
years; and to emphasize recent developments especially in electrochemistry, and on dialdehyde
and diacid chemistry
352 citations
TL;DR: Application of hypervalent iodine(III) compounds allows mild and highly selective oxidative transformations in a facile and environmentally friendly manner.
Abstract: This review summarizes the chemistry of hypervalent iodine(III) compounds with emphasis of their synthetic applications. The preparation and reactions of (difluoroiodo)arenes, (dichloroiodo)arenes, iodosylarenes, (bis(acyloxy)iodo)arenes, and aryliodine(III) organosulfonates are overviewed. Application of these reagents allows mild and highly selective oxidative transformations in a facile and environmentally friendly manner. Some of these useful transformations can be carried out using organoiodine(III) compounds as catalysts or recyclable reagents.
264 citations
TL;DR: The main sources of molecules with antimycotic activity obtained from the natural environment are reviewed, particularly among medicinal plants and compounds isolated from them used for their empirically antifungal properties.
Abstract: The spread of multidrug-resistant strains of fungus and the reduced number of drugs available, makes it necessary to discover new classes of antifungals and compounds that inhibit these resistant mechanisms. This has led to a search for therapeutic alternatives, particularly among medicinal plants and compounds isolated from them used for their empirically antifungal properties. In these natural sources, a series of molecules with antifungal activity against different strains of fungus have been found, which are of great importance to humans and plants. In this article, we review the main sources of molecules with antimycotic activity obtained from the natural environment.
247 citations
TL;DR: Nicotinic and isoniazid derivatives, most of them containing nitro groups were synthesized by this group, and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv using the Alamar Blue susceptibility test and the activity expressed as the minimum inhibitory concentration (MIC) in mg/mL.
Abstract: Several nicotinic and isoniazid derivatives, most of them containing nitro groups were synthesized by our group, and evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv using the Alamar Blue susceptibility test and the activity expressed as the minimum inhibitory concentration (MIC) in mg/mL. The compound 11d exhibited the best result (1.2 µg/mL) when compared with first line drugs such as isoniazid (INH) and rifampicin (RIP). Therefore this class of compounds could be a good starting point to develop new lead compounds in the treatment of multi-drug resistant tuberculosis.
231 citations
TL;DR: The interesting and most usefull knowledge on lapachol, which is reviewed in this paper, can be used as a starting point in future research endeavors.
Abstract: Lapachol is a naphthoquinone that was first isolated by E. Paterno from Tabebuia avellanedae (Bignoniaceae) in 1882. A wide spectrum of therapeutic activities have been attributed to lapachol or its derivatives viz., anti-abscess, anti-ulcer, antileishmanial, anticarcinomic, anti- edemic, anti-inflammatory, antimalarial, antiseptic, antitumor, antiviral, bactericidal, fungicidal, insectifugal, pesticidal, protisticidal, respiradepressant, schistosomicidal, termiticidal, and viricidal. Originally isolated from species of the Bignoniaceae family, lapachol can also be found in other families such as Verbenaceae, Proteaceae, Leguminosae, Sapotaceae, Scrophulariaceae, and Malvaceae. The interesting and most usefull knowledge on lapachol, which is reviewed in this paper, can be used as a starting point in future research endeavors.
188 citations