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Showing papers in "Brain Research in 1967"


Journal ArticleDOI
TL;DR: The original, non-suppressive Natua method for impregenation of terminal degeneration has been modified by the introduction of a potassium permanganate-uranyl nitrate sequence, resulting in a selective impregnation of degenarated axons inclusive of their synaptic thickenings.

1,669 citations


Journal ArticleDOI
TL;DR: It was found that a sharp increase in the number of synaptic junctions occurs in rat cortex (molecular layer) during the 3rd and 4th postnatal weeks, and it is proposed that synapticJunctions evolve through several stages and a tentative morphogenetic scheme is presented.

677 citations


Journal ArticleDOI
TL;DR: It was found that when the cortical projections are viewed in a temporofrontal sequence, their terminal distribution in the brain stem tends to shift from dorsal to ventral and medial, and the temporal, occipital and caudal parietal areas project primarily to the superior colliculus and to auditory nuclei.

634 citations


Journal ArticleDOI
TL;DR: The medial preoptic-anterior hypothalamic continuum appears to be quite compatible with the present physiological evidence that it is virtually involved in mating behavior, and is situated intermediate between the limbic and olfactory telencephalon and borders the gonadotropic mechanisms of the tuberal hypothalamic region.

397 citations





Journal ArticleDOI
TL;DR: It is concluded that nucleus ovoidalis represents a specific diencephalic auditory relay nucleus, possibly comparable to the ventral division (Morest) of the mammalian medial geniculate nucleus.

271 citations


Journal ArticleDOI
TL;DR: The detection of this close correlation and the finding that synaptic networks form in tissue completely isolated from normal afferent and efferent connections are considered the most significant contributions of this communication.

212 citations


Journal ArticleDOI
TL;DR: It was concluded that the vagal afferent system is comprised of fiber groups which are able to initiate and maintain either synchronization or desynchronization of the EEG and that these fiber groups are both functionally and structurally discrete.

204 citations


Journal ArticleDOI
TL;DR: It has been concluded that, in the mouse at least, climbing fibers make synaptic contacts with the Purkinje cell on spines, and the suggestion made by Uchizono that synaptic vesicles of excitatory and inhibitory synapses have different morphological characteristics has been confirmed.

Journal ArticleDOI
TL;DR: Intracellular recordings from neurons of the substantia nigra have disclosed 3–4 msec latency EPSPs and succeeding IPSPs in response to ipsilateral stimulation of the head of the caudate nucleus, and the electrophysiological data are discussed in terms of the possible histological features of nigro-caudate connections.

Journal ArticleDOI
TL;DR: Negligible differences were found between 3 and 6-day deprived rats in compensation for lost REM time on recovery days, suggesting a ‘plateau’ effect.

Journal ArticleDOI
TL;DR: The present study has attempted to correlate the distribution and orientation of the motoneuron dendrites with the somatotopically organized distribution of their cell bodies with reference to both the maintenance of specificity of the afferent supply to the mot oneurons and the activation of synergistic motoneurons.

Journal ArticleDOI
TL;DR: Retinal projections in the European hedgehog are primarily to the contralateral superior colliculus, pretectal complex and pars dorsalis and ventralis of the lateral geniculate body and an inferior accessory optic fasciculus appears to be lacking.

Journal ArticleDOI
TL;DR: The adrenergic transmitter, NA, can now be visualized by a highly specific fluorescence microscopical method, and the finding of peripherally located adrenergic neurons and especially the adrenergic synapses in autonomic ganglia show that the autonomic nervous system is built both anatomically and functionally in a more complex way than hitherto thought.

Journal ArticleDOI
TL;DR: Synthetic oligonucleotide probes are used to investigate the tissue distribution and cellular localization of mRNAs encoding the two classes of amyloid β-protein precursors.

Journal ArticleDOI
TL;DR: Hemisections of the spinal cord were made at various levels between the 2nd and the 27th spinal segment in 12 Tegu lizards and fiber degeneration was demonstrated with the Nauta method and traced rostrally as follows.


Journal ArticleDOI
TL;DR: The distribution patterns and orientations of degenerating dorsal root fibers were examined in segments C6-T1 of Rexed's lamina I and the predominant dendritic orientations in the various laminae.

Journal ArticleDOI
TL;DR: A thalamo-cortical system with origins in the midline nonspecific thalamic nuclei and projections to the orbitofrontal granular cortex has been identified with an electrocortical synchronizing function related to internal inhibition, which has resulted in 3 effects.

Journal ArticleDOI
TL;DR: The discussion emphasizes the likelihood that the tecto-rotundo-ectostriatal mechanism subserves vision and may be the major pathway by which visual information reaches the avian telencephalon.

Journal ArticleDOI
TL;DR: Later developments in function correlate with a marked increase in the abundance of synapses, as the explants mature in culture, and concomitant increase in complexity of the synaptic ultrastructure.

Journal ArticleDOI
TL;DR: The changes in protein, nucleic acids, aspartate amino transferase, and aspartates transcarbamoylase during postnatal development of the cerebral cortex and cerebellum of the rat have been studied.


Journal ArticleDOI
TL;DR: It is demonstrated that the junctional complexes from brain synapses may be isolated and their receptor properties studied, and while these enzymes have a wider distribution, which includes the limiting membrane of the ending, the cholinergic receptor is localized in the junctionAL complex, probably at the subsynaptic membrane.

Journal ArticleDOI
TL;DR: The effect of the non-ionic detergent Triton X-100 on several subcellular fractions from rat brain was studied with a special emphasis on the solubilization effect on protein and membrane-bound enzymes, finding that the junctional complexes which comprise the synaptic membranes and the subsynaptic web appear to be more resistant to the action of the detergent.

Journal ArticleDOI
TL;DR: Maturation of evoked cortical responses to visual and auditory stimulation was investigated in normal as well as in acute and chronically starved cats, with marked changes observed in early periods of postnatal life.


Journal ArticleDOI
TL;DR: Intracellular recordings were obtained from neurons in the head of the caudate nucleus during medial and intralaminar (MTh) and ventrolateral (VL) thalamic stimulation, finding that EPSPs develop with the augmenting response in cortex and are attributed largely to involvement of intrathalamic pathways from VL to nonspecificThalamic nuclei, thence to caudates.