Showing papers in "Cancer in 1953"

Testicular tumors. A clinicopathological study

Abstract: Summary The classification of testicular tumors arrived at in this study is based on both the morphological and the biological characteristics of the tumors. The primary division of testicular tumors is into (1) the germinal tumors, which arise from germ cells and make up 96.5 per cent of this series, and (2) the nongerminal tumors, a miscellaneous group of neoplasms arising from the nongerminal elements of the testis and comprising 3.5 per cent of this series. The germinal tumors are composed of any one or any combination of four morphological tumor patterns: seminoma, embryonal carcinoma, teratoma, and choriocarcinoma. On the basis of biological behavior and apparent morphogenesis, the fifteen possible morphological varieties of tumors can be put in five groups: I. seminoma, pure; II. embryonal carcinoma, pure, or with seminoma; III. teratoma, pure, or with seminoma; IV. teratoma with either embryonal carcinoma or choriocarcinoma or both, and with or without seminoma; V. choriocarcinoma, pure, or with either embryonal carcinoma or seminoma or both.

Aneurysmal bone cyst; further observations.

Abstract: N 1950 THE WRITER3 DREW ATTENTION to a disI tinctive lesion of bone designated “aneurysma1 bone cyst,” basing his discussion upon eight relevant cases observed within the previous year, as well as a backlog of experience with the condition dating back to 1942.2 The affected bone site, whatever its location may be, is completely transformed and ultimately resembles a peculiarly expanded, blood-filled sponge that, if untreated, may eventually reach an impressive size. The communicating pools of venous blood within this reservoir are bordered by connective-tissue septa showing giantcell reaction, especially within fields of blood extravasation, as well as more or less conspicuous reparative new-bone formation indicating attempted reconstruction. T h e progress of the condition may be arrested by curettement (which need not be complete) and ,apparently also by radiation therapy. The practical importance of its recognition, otherwise, lies in the fact that clinically i t is often regarded as a neoplasm despite its rather distinctive roentgenological appearance and hence is treated more aggressively than is necessary. Specifically, although without any real justification, the lesion is still commonly mistaken for giant-cell tumor-so-called atypical, subperiosteal, giant-cell tumor-and occasionally for hemangioma and even osteogenic sarcoma. In an appreciabIe number of instances seen by the writer in consultation, the roentgenograms had been interpreted as indicative of a sarcoma. In several cases, the initial pathological diagnosis was that of giant-