Showing papers in "Clinical Toxicology in 1972"
TL;DR: The effect of dietary selenium on N-2 Fluorenyl-Acetamide (FAA)-Induced Cancer in Vitamin E Supplemented, Selenium Depleted Rats was discussed in this paper.
Abstract: (1972). Effect of Dietary Selenium on N-2 Fluorenyl-Acetamide (FAA)-Induced Cancer in Vitamin E Supplemented, Selenium Depleted Rats. Clinical Toxicology: Vol. 5, No. 2, pp. 187-194.
100 citations
TL;DR: In this paper, Congenital Deformities in Lambs, Calves, and Goats resulted from Maternal Ingestion of Veratrum californicum; Hare Lip, Cleft Palate, Ataxia, and Hypoplasia of Metacarpal and Metatarsal Bones.
Abstract: (1972). Congenital Deformities in Lambs, Calves, and Goats Resulting from Maternal Ingestion of Veratrum californicum; Hare Lip, Cleft Palate, Ataxia, and Hypoplasia of Metacarpal and Metatarsal Bones. Clinical Toxicology: Vol. 5, No. 2, pp. 245-261.
56 citations
TL;DR: In this article, Selenium poisoning in domestic animals and its relationship to man is discussed. But the authors do not discuss the relationship between poisoning and human health and do not consider the effects of poisoning on humans.
Abstract: (1972). Selenium Poisoning in Domestic Animals and Its Relationship to Man. Clinical Toxicology: Vol. 5, No. 2, pp. 175-186.
51 citations
TL;DR: (1972).
Abstract: (1972). Mechanisms of Heavy Metal Toxicities. Clinical Toxicology: Vol. 5, No. 2, pp. 151-167.
51 citations
TL;DR: In this article, Osmometry in the Evaluation of Alcohol Intoxication is used to evaluate the effect of alcohol on the human brain and the brain's ability to process it.
Abstract: (1972). Osmometry in the Evaluation of Alcohol Intoxication. Clinical Toxicology: Vol. 5, No. 3, pp. 343-363.
37 citations
TL;DR: A Fatal Case Involving Methylenedioxyamphetamine was reported in this article, where the case involved a single injection of the drug and the patient was found to have died.
Abstract: (1972). A Fatal Case Involving Methylenedioxyamphetamine. Clinical Toxicology: Vol. 5, No. 1, pp. 3-6.
32 citations
TL;DR: The Biological Activities and Detection of Naturally Occuring 12,13-Epoxy-δ'-Trichothecenes as mentioned in this paper was a seminal work in the field of toxicology.
Abstract: (1972). The Biological Activities and Detection of Naturally Occuring 12,13-Epoxy-δ'-Trichothecenes. Clinical Toxicology: Vol. 5, No. 4, pp. 495-515.
29 citations
TL;DR: In this paper, the authors describe the sequential development of the Lesions in Locoweed Poisoning, and present a method to identify the lesion locations in the locoweed.
Abstract: (1972). Sequential Development of the Lesions in Locoweed Poisoning. Clinical Toxicology: Vol. 5, No. 4, pp. 575-580.
29 citations
TL;DR: Fluoride standards and a comprehensive guide for use in diagnosing and evaluating fluoride toxicity in animals have been compiled and the lesions observed in fluorideoxicity in various species of animals are essentially similar.
Abstract: Fluoride toxicity in animals has become an important toxicologic problem in many parts of the world due to the expansion of certain types of industrial operations that emit excessive fluorides into the atmosphere in areas of animal habitat. Animals normally ingest low levels of fluoride with no adverse effects. Small amounts of fluoride may even have beneficial effects, but when excessive amounts are ingested for prolonged periods of time, adverse effects are induced. Many sources may contribute to the total fluoride intake of animals. Various factors influence biologic responses of animals to excessive ingested fluorides. Signs and lesions of fluoride toxicity in animals have been characterized. The lesions observed in fluoride toxicity in various species of animals are essentially similar. Fluoride standards and a comprehensive guide for use in diagnosing and evaluating fluoride toxicity in animals have been compiled. Prevention and control of fluoride toxicity in animals can be achieved when th...
28 citations
TL;DR: In this article, known and suspected teratogenic hazards in range plants are described and compared. But none of them are considered to be related to the ones discussed in this paper.
Abstract: (1972). Known and Suspected Teratogenic Hazards in Range Plants. Clinical Toxicology: Vol. 5, No. 4, pp. 529-565.
27 citations
TL;DR: The British Anti-Lewisite (BAL), the Classic Heavy Metal Antidote, is considered to be a classic heavy metal antidote.
Abstract: (1972). British Anti-Lewisite (BAL), the Classic Heavy Metal Antidote. Clinical Toxicology: Vol. 5, No. 2, pp. 215-222.
TL;DR: In this paper, the Syndromes of Locoweed Poisoning in Livestock were identified and a classification of the most common types of poisonings was given for each of them.
Abstract: (1972). Syndromes of Locoweed Poisoning in Livestock. Clinical Toxicology: Vol. 5, No. 4, pp. 567-573.
TL;DR: In this paper, the authors present an analytical method for mycotoxins, which they call Analytical Methods for Mycotoxin Analysis (AMEA) for the purpose of mycotoxin detection.
Abstract: (1972). Analytical Methods for Mycotoxins. Clinical Toxicology: Vol. 5, No. 4, pp. 465-494.
TL;DR: Adsorption of Propoxyphene Hydrochloride by Activated Charcoal by Activator Charcoal is inhibited by the following substance: carbon dioxide, carbon monoxide, and carbon dioxide.
Abstract: (1972). Adsorption of Propoxyphene Hydrochloride by Activated Charcoal. Clinical Toxicology: Vol. 5, No. 3, pp. 317-329.
TL;DR: A collaborative research project involving the Suburban Hospital and the Laboratory of Chemistry and the National Heart and Lung Institute of the National Institutes of Health, both of Bethesda, Md, concluded that a satisfactory method involving mass spectrometry has been developed and been in routine use for fourteen months.
Abstract: Over one year ago, it became very clear to us that the management of patients suffering from overdoses of drugs could be conducted with an increased amount of confidence once the identity of the drug or drugs involved had been established, With this in mind, we embarked upon a collaborative research project involving the Suburban Hospital and the Laboratory of Chemistry of the National Heart and Lung Institute of the National Institutes of Health, both of Bethesda, Md Various techniques for securing the above information were studied and a satisfactory method involving mass spectrometry has been developed [ 11. This has been in routine use for fourteen months and the purpose of this paper is to report some of the results obtained during this period. In a middle class, suburban community such as Bethesda, overdoses of the more notorious drugs such as the opiates represent less of a problem on a day-to-day basis than do overdoses of prescribed drugs such as sedatives and tranquillizers. In cases where massive quantities of such compounds have been consumed by the patient, routine supportive therapy may often be deemed inadequate and recourse may be made to more aggressive detoldfication methods such as hemo- and peritoneal dialysis. Before such measures can be initiated however, reliable identification of the drug or drugs involved is necessary. It is well known that gas-liquid chromatography is an excellent 17
TL;DR: The use of Resin Hemoperfusion in the Treatment of Acute Drug Intoxication and its applications in Clinical Toxicology are described.
Abstract: (1972). The Use of Resin Hemoperfusion in the Treatment of Acute Drug Intoxication. Clinical Toxicology: Vol. 5, No. 3, pp. 331-335.
TL;DR: In this article, a Pseudohyperosmolar Nonketoacitotic Coma Due to Oxazepam Intoxication was reported, which was the first case of its kind.
Abstract: (1972). Pseudohyperosmolar Nonketoacitotic Coma Due to Oxazepam Intoxication. Clinical Toxicology: Vol. 5, No. 3, pp. 337-341.
TL;DR: In this article, the authors describe the research activities of a Veterinary Toxicology Laboratory (VTL) in the early 1970s and discuss their work in the field of clinical toxicology.
Abstract: (1972). Research Activities of a Veterinary Toxicology Laboratory. Clinical Toxicology: Vol. 5, No. 2, pp. 271-281.
TL;DR: In this article, the advantages of a unit dose drug distribution system in surveillance of adverse drug reactions are discussed, and the authors conclude that the system is more efficient than a single unit dose distribution system.
Abstract: (1972). Advantages of a Unit Dose Drug Distribution System in Surveillance of Adverse Drug Reactions. Clinical Toxicology: Vol. 5, No. 3, pp. 405-417.
TL;DR: In this paper, the influence of environmental factors of mycotoxin toxicity as evidenced by studies with Aflatoxin is discussed. But the authors do not consider the effect of environmental influences on mycotoxins.
Abstract: (1972). Influence of Environmental Factors of Mycotoxin Toxicity as Evidenced by Studies with Aflatoxin. Clinical Toxicology: Vol. 5, No. 4, pp. 517-528.