Showing papers in "Clinics and Research in Hepatology and Gastroenterology in 2022"

TL;DR: In this article , the authors conducted a meta-analysis to evaluate the efficacy of statins in the treatment and the development of non-alcoholic fatty liver disease (NAFLD).

TL;DR: In this paper , the authors discuss the epidemiology of COVID-19 and liver dysfunction as well as potential mechanisms underlying the association between liver dysfunction or other preexisting liver diseases, including direct cholangiocyte damage induced by SARS-COV-2, cytokine storm and drug-induced liver injury.

TL;DR: In this paper , the authors conducted a meta-analysis to evaluate the efficacy of three novel glucose-lowering drug classes, namely glucagon-like peptide-1 receptor agonists (GLP-1RA), sodium-glucose co-transporter 2 (SGLT2) inhibitors, and dipeptidyl-peptide-decrease-4 (DPP4) inhibitors on hepatic parameters.

TL;DR: In this paper, the role of neutrophil extracellular traps (NETs) in procoagulant activity (PCA) in patients with NASH remains unclear.

TL;DR: In this article , the authors conducted a systematic review and meta-analysis of all randomized controlled trials (RCTs) which studied the efficacy and safety of AT-1001 in patients with celiac disease.

TL;DR: In this paper , the authors investigated liver injury, clinical features, and risk factors in patients with mild, moderate, and severe Coronavirus disease 2019 (COVID-19) and found that patients with high fibrosis-4 index had a 3-fold greater risk of severe disease.

TL;DR: In this article, the authors conducted a systematic review and meta-analysis of all randomized controlled trials (RCTs) which studied the efficacy and safety of AT-1001 in patients with celiac disease.

TL;DR: In this article , the role of neutrophil extracellular traps (NETs) in procoagulant activity (PCA) in patients with NASH remains unclear.

TL;DR: A review of the current knowledge of the regulation and the contribution peripheral and central signals at each step of the cycle to control appetite is presented in this paper , which highlights the increasingly complex understanding of regulation and action mechanisms intervening in the gut-brain axis.

TL;DR: In this article , the latest evidence on gastrointestinal, hepato-biliary, and pancreatic manifestations in children with coronavirus disease-19 and multisystem inflammatory syndrome will be analyzed.

TL;DR: In this article , the authors explored the relationship between adipose tissue dysfunction and metabolic dysfunction associated fatty liver disease (MAFLD) in obesity on the scene of COVID-19 and found that obese individuals can become a target of SARS-Cov-2 infection, although major liver damage is uncommon.

TL;DR: In this article , the authors investigated whether inflammasomes activation is upregulated in patients with NAFLD and the upregulation can be attenuated by anthocyanins, which are polyphenols with known anti-inflammatory activities.

TL;DR: In this paper , the authors investigated the efficacy of camrelizumab plus transarterial chemoembolization (TACE) on massive hepatocellular carcinoma (HCC) patients.

TL;DR: In this article , the potential of genetic factors and their translation into the design of novel therapeutics, as well as their implications for future research into personalized medications using microbiota using microbial colonization and dysbiosis reversal.

TL;DR: In this article , the effects of semaglutide (recent GLP-1) by analyzing the liver mTORC1/AMPK pathway genes in obese mice were investigated.

TL;DR: In this article , a meta-analysis study showed that metformin use was associated with a decreased risk of hepatocellular carcinoma (HCC) in DM patients with a random effects model (OR/RR = 0.59, 95% CI 0.51-0.68, I2 = 96.5%, p < 0.

TL;DR: EncephalApp_Stroop is a smartphone-based application established as screening tool for the diagnosis of minimal hepatic encephalopathy (MHE) but has not yet been validated in a German cohort and country specific cut-offs are currently missing as mentioned in this paper .

TL;DR: The copper/total copper ratio (COTR) is a new specific biological marker, useful for the diagnosis of Wilson's disease and alpha-1 antitrypsin deficiency as discussed by the authors .

TL;DR: In this article , the influence of RAGE and HMGB1 signalling in patients with primary sclerosing cholangitis (PSC) was analyzed by ELISA analysis.

TL;DR: In this paper , the authors describe the techniques, safety and efficacy of transjugular transcaval intrahepatic portosystemic shunt (TTIPS) procedures in case of unfavourable anatomy.

TL;DR: The diagnosis of rare genetic liver diseases can be strongly suggested with specific non-invasive tests as discussed by the authors, which can result in multi-systemic damage, which may compromise the patient's prognosis.

TL;DR: In this article, the authors revealed the expression, function and underlying molecular interactions of USP11 in gastric cancer using immunohistochemistry and ELISA, and showed that USP-11 level was not regulated by HER3 and vice versa.

TL;DR: In this paper , a review aims to summarize the recent literature as an aid to better understand how the alteration of gut microbiota composition contributes to insomnia while evaluating and prospecting the therapeutic effect of modulating gut microbiota in the treatment of insomnia based on previous publications.

TL;DR: In this article , the authors describe the population of cirrhotic patients who were transplanted from the ICU in France, identifying pre-transplant risk factors of posttransplant mortality and describing geographic variations in ICU transplant activity.

TL;DR: In this paper , the authors provided a comprehensive and systematic report of the currently published risk factors for complicated infectious pancreatic necrosis in patients with severe acute pancreatitis by meta-analysis of published retrospective case-control studies.

TL;DR: In this paper , the authors revealed the expression, function and underlying molecular interactions of USP11 in gastric cancer using immunohistochemistry and ELISA, and showed that USP-11 level was not regulated by HER3 and vice versa.

TL;DR: A systematic literature search on PUBMED and EMBASE was conducted as discussed by the authors , where the authors presented an analysis of the latest developments and also proposed an algorithm for screening pediatric patients at risk for NAFLD.