Showing papers in "Computers and Biomedical Research in 1968"

TL;DR: Patients, when interfaced in conversation with a computer programmed as a model of the physician interviewer, have been found to react positively to the experience.

TL;DR: A language for the simulation of the kinetic behavior of complex chemical or biochemical systems is described and defined, written in FORTRAN IV and should run on any medium or large size batch-processing computer.

TL;DR: A more complex programming system for a variable-length and variable-format computer-stored medical record that allows multiple medical funtions to operate simultaneously and permit access to the same patient's records.

TL;DR: Although the numerical results that are presented simulate the known mechanical behavior of the lung, any detailed interpretation must be approached cautiously at this time since many of the components and parameters of the model necessarily had to be chosen arbitrarily for lack of good experimental data.

TL;DR: The logic for the contour analysis programs and the results of a comparison of computer and physician diagnosis for over two thousand cases are described and the effectiveness of the program as a screening tool is considered.

TL;DR: A simplified model of the blood-glucose regulatory system has been conformed to data from glucose-tolerance tests in nondiabetics and indicated that the assumption of a single regulatory hormone such as insulin was adequate to fit most normal responses.

TL;DR: The logic of the measurement program determines from the waveform the identity and nature of the various electrocardiogram complexes and identifies their amplitude and time-duration characteristics.

TL;DR: The algorithm uses as its input the information from the measurement section described in the preceding paper to determine the nature of the basic rhythm and any other important events (such as ectopic beats).

TL;DR: Using this procedure, the choice of an appropriate model is made from computed results, and the subjective bias often associated with hand-drawn graphical methods is avoided.

TL;DR: This model suggests that the activity of many enzymes is a function of several Glycolytic intermediates or products arranged to slow the rate of glycolysis as gly colytic products pile up.

TL;DR: The mathematical approach to diagnosis was examined in a group of 1,184 patients with congenital heart disease using a rather limited number of symptoms using a Fortran program which works out the a priori probabilities of 94 different malformations and the conditional probabilities of the 46 symptoms in the patient studied according to Bayes' formula.

TL;DR: Analog simulations have been performed to test inherent approximations and to determine the relative importance of some of the biological mechanisms involved in blood-glucose regulatory system regulation.

TL;DR: A cardiovascular alarm system formed part of an on-line real-time computer based physiological monitoring and measuring system in a post cardiac surgical intensive care unit was analyzed, and a postulate which might eliminate most of the false alarms was devised.

TL;DR: Regulation of glycolysis during sustained oscillations has been studies by simulating in detail the experimentally observed behavior of a supernatant fraction from beef heart using a model consisting of 57 simultaneous differential equations representing 101 chemical reactions.

TL;DR: The use of a digital computer to calculate cardiac catheterization data has been studied and the equipment and programming logic used by the laboratory are described.

TL;DR: In this article, a digital computer program has been described for automatic interpretation of cardiac arrhythmias, focusing on determining the diagnostic information which can be obtained by considering only the temporal location of the P and R waves without regard to their shape.

TL;DR: Results showed that diagnostic accuracy increased dramatically with increases in the numerical differences between the maximal values and the competing values of the probabilities and discriminant functions.

TL;DR: A much faster method is described, where the differential equations representing the behavior of an enzyme are replaced by an algebraic rate law, and a program for deriving and assembling systems of these rate laws is described.

TL;DR: A program has been worked out to locate by computer the centromere on digitalized images of chromosomes, and the basic criteria of the program, called FOSCAN, consist of scanning the digitalized chromosome along parallel lines in a suitable direction selected in such a way as to be nearly perpendicular to the mean direction of the chromosome arms.

TL;DR: Electrocardiograms were placed on magnetic tape or transmitted over telephone wires to a 1401 computer using a data gathering console developed especially for the task using an analog preprocessor used to select certain points on the waveform as particularly valuable for analysis by the computer.

TL;DR: A conversational computer system allowing direct communication between scientist and computer-driven experiment is described, and a file structure is built in to the system enabling a scientist to have results from previous experiments available.

TL;DR: In 332 brachial pulse wave records comparisons between statistics calculated from the computer identified points with corresponding measurements calculated from points identified by an experienced physician showed correlation coefficients varying between .94 and .99 indicating good agreement.

TL;DR: The PERT technique has been applied to a medical research project, “The Surgical Treatment of Emphysema, the Selection of Patients and the Evaluation of Results” at the Toronto General Hospital, and it is suggested that this technique can be used successfully in complex medical research work.

TL;DR: In the resting dog who displays a marked sinus arrhythmia, a model of stroke volume control was tested by a procedure of vectorial reconstruction andSympathetic discharge to the heart appears to cause no changes in stroke volume in these resting animals.

TL;DR: Results during the recovery phase show that the model developed in this study fits the data better than an exponential model, and indicate that the parameters of the model for the exercise phase may be useful as criteria for a functional classification of cardiovascular performance.

TL;DR: Animals infected with a strain of Pseudomonas aeruginosa were found to be depleted of blood glucose and liver glycogen and the results suggest that the infected animals do not synthesize glucose from glycolytic pathway precursors at a normal rate.

TL;DR: The rhythm disturbances a cardiac patient may undergo during his stay in a coronary care unit are simulated by a digital computer, which displays electrocardiograms and other information on an oscilloscope.

TL;DR: A computer program has been designed to assist in the teaching of cardiac arrhythmias at various levels of training and some features of the program are described.

TL;DR: A commonly used uniform random-number generator is examined in light of a genetic-simulation problem and proves defective, suggesting that any proposed generator be checked for the properties needed by the simulation problem at hand.