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Showing papers in "Contraception in 1995"


Journal ArticleDOI
TL;DR: Women who were inconsistent OC users, missing one or more pills per cycle, were almost three times as likely to experience an unintended pregnancy while using OCs than were women who took their OCs consistently.

345 citations


Journal ArticleDOI
TL;DR: The negative effects reported may be less evident in women using the COC for contraceptive purposes but may lead to discontinuation in some women and warrant further investigation.

185 citations


Journal ArticleDOI
TL;DR: It is suggested that long-term treatment with an oral monophasic contraceptive formulation (ethinylestradiol 20 micrograms + desogestrel 0.150 mg) did not modify the BMD but prevented the occurrence of the physiologic peak of bone mass in young women.

153 citations


Journal ArticleDOI
TL;DR: It is warranted to probe deeply into their precise dose/immuno-effect relationship in the safety evaluation of compounds isolated from Tripterygium wilfordii, if the immuno-suppressive dose of a drug is much higher than its antifertility dose, it could yet be regarded as a safe contraceptive.

153 citations


Journal ArticleDOI
TL;DR: The levonorgestrel-releasing intrauterine device LNg IUD is a new contraceptive method that combines the advantages of both hormonal and intrauterines contraception and can be used as an effective therapy for menorrhagia.

137 citations


Journal ArticleDOI
TL;DR: Drospirenone represents a novel type of synthetic progestogen since it combines potent progestogenic characteristics with antimineralocorticoid and antiandrogenic activity and is anticipated to give rise to a number of additional health benefits both for users of oral contraceptives and hormone replacement therapy recipients.

130 citations


Journal ArticleDOI
TL;DR: Good compliance has been linked with patient satisfaction with the clinician, the absence of certain side effects, establishing a regular daily routine to take OCs, and reading information distributed with OC packaging.

127 citations


Journal ArticleDOI
TL;DR: A profound suppression of androgen levels and peripheral androgen metabolism is demonstrated in women using a triphasic oral contraceptive and a monophasic formulation containing EE/NGM.

111 citations


Journal ArticleDOI
TL;DR: An increase in bone density during treatment with levonorgestrel and stable values during short-term administration of DMPA, in standard clinical doses for contraception are suggested.

101 citations


Journal ArticleDOI
TL;DR: A meta-analysis of published literature on the relationship between IUD use and the risk of ectopic pregnancy found that a pregnancy with an IUD in situ is more often an ectopic one than aregnancy with no IUD.

100 citations


Journal ArticleDOI
TL;DR: The current knowledge of the association between contraceptive methods and the risk of ectopic pregnancy was evaluated by means of a meta-analysis and common Odds Ratios (COR) and 95% confidence intervals were calculated if homogeneity was not rejected.

Journal ArticleDOI
TL;DR: While results among treatment groups differed slightly, no significant weight change occurred in any of the treatment groups.

Journal ArticleDOI
TL;DR: Oral contraceptives may influence the recurrence of symptomatic vulvovaginal candidiasis, and patients with recurrent infection were more likely to use oral contraception and to have a higher frequency of monthly intercourse.

Journal ArticleDOI
Jan Endrikat1, M.-A. Jaques1, M. Mayerhofer1, C. Pelissier1, U. Müller1, B. Düsterberg1 
TL;DR: In this paper, the authors compared contraceptive reliability, cycle control, and tolerance of an oral contraceptive containing 20 micrograms ethinylestradiol (EE2) and 75 microgram gestodene (GSD), with a reference preparation containing a similar dose of gestoderene but in combination with 30 microgram's ethinylstradiol.

Journal ArticleDOI
TL;DR: Continuing bleeding patterns were more prominent in the levonorgestrel implant and oral norethindrone groups than in patients receiving depo-medroxyprogesterone acetate, and no significant weight gain was detected in any group.

Journal ArticleDOI
TL;DR: Women from developed countries apparently tolerate an increased MBL of approximately 55% without developing iron deficiency anemia and iron stores were unchanged indicating an adequate adaptive increase in intestinal iron absorption.

Journal ArticleDOI
TL;DR: The effectiveness of Norplant implants over a seven year period of continuous use was studied in a multicenter trial and the pregnancy rate neither reached nor exceeded 1 per 100 woman years in any 5 year age group or in any 10 kg weight group.

Journal ArticleDOI
TL;DR: Over two-thirds of the cases have ovulatory cycles after long-term use of Lng-IUD; the contraceptive effect is mainly due to its local action on the endometrium, with much less effect on the ovarian function.

Journal ArticleDOI
TL;DR: The clinical experience with a combined oral contraceptive (COC) containing 150 micrograms desogestrel and 30 microgram ethinylestradiol is reviewed in this paper.

Journal ArticleDOI
TL;DR: Ten Chinese women who had menorrhagia without organic cause and suffered from anaemia were treated with levonorgestrel intrauterine device and there was a 54, 87 and 95% reduction in menstrual blood loss when compared with the pretreatment cycle.

Journal ArticleDOI
TL;DR: Oral misoprostol is better than vaginal gemeprost for cervical dilatation prior to vacuum aspiration in first trimester pregnancy, and is also much cheaper and more convenient to use.

Journal ArticleDOI
TL;DR: Sixty-three normal Caucasian men were administered intramuscular testosterone enanthate (TE) 200 mg i.m. weekly for 12 months as part of a male contraceptive trial, which caused a 2.5-fold increase in trough serum testosterone concentrations.

Journal ArticleDOI
TL;DR: In contrast to progesterone, which showed antiandrogenic activity, gestodene and 3-keto-desogestrel both exhibited androgenicActivity, and all three progestins exhibited weak GR-mediated antagonistic activity, while 3-Keto-desgestrel showed neither antimineralocorticoid nor mineralocortsicoid action.

Journal ArticleDOI
TL;DR: The data provide little evidence of increasing depression with long-term use of DMPA and no evidence of a short-term effect of dose (within the contraceptive range) on mood.

Journal ArticleDOI
TL;DR: Their correlated reduction in impact on insulin concentrations, though small, suggests common mechanisms through which OC affect blood pressure and insulin.

Journal ArticleDOI
TL;DR: Pregnant Hispanic teenagers have poorer communication with their parents than do other Hispanic teens, and efforts to reduce the incidence of adolescent pregnancy among Hispanics may need to address not only family communication but also issues outside the home such as alcohol and recreational drugs.

Journal ArticleDOI
TL;DR: A single Nestorone subdermal implant affords efficient contraceptive protection during two years during treatment and in vivo release rate was 45-50 micrograms/day.

Journal ArticleDOI
TL;DR: It was observed that the women having frequent or prolonged bleeding had discontinued the contraceptive method more often as compared to those having delayed bleeding episodes or oligomenorrhoea, however, discontinuation rates due to bleeding irregularities at one year were lower in Norplant-II implants users asCompared to other long acting hormonal contraceptive methods such as injectables or IUDs.

Journal Article
TL;DR: Twenty-four experts from around the world, representing the fields of research, policy, communications, women's advocacy and medicine, gathered at the Rockefeller Foundation Conference Center in Bellagio, Italy, in April 1995 to discuss emergency contraception.

Journal ArticleDOI
TL;DR: The 20 micrograms EE preparation was not found to lead more often to ovarian follicles or cysts when compared with a 35 microgramS EE preparation, possibly because of the type and dose of the progestogen used.