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Showing papers in "Experimental Parasitology in 1962"


Journal ArticleDOI
TL;DR: Evidence is produced which suggests that mast cells play a part in cellular reactions to parasitic infection, and the theory that eosinophils act as antagonists to histamine is supported.

89 citations


Journal ArticleDOI
TL;DR: Evidence is presented that the mucopolysaccharide isolated constitutes the principal structural material of the laminated membrane of hydatid cysts, and the antigen of Dennis is shown to be a relatively pure protein.

57 citations


Journal ArticleDOI
TL;DR: Separation and identification of the radioactive metabolic intermediates formed when adults and miracidia of Fasciola hepatica were incubated with glucose and succinate have shown that glycolytic pathways are present and an increase in the life span of miracidia in media containing added substrates has been demonstrated.

42 citations


Journal ArticleDOI
TL;DR: A fluorescent antibody test for trichinosis, employing T. spiralis larvae as antigen and possessing a high degree of sensitivity and specificity, was described in this paper, where reliable qualitative and quantitative results were obtained either with fresh sera or dried blood specimens on absorbent paper.

41 citations


Journal ArticleDOI
TL;DR: It is concluded from these results that the presence of living S. mansoni worms, even though sexually immature, can stimulate acquired resistance to the parasite, and that the existence of eggs is not essential for the development of this resistance.

41 citations


Journal ArticleDOI
TL;DR: The development of large populations of lice on mice disabled by amputation of both rear limbs indicates that this paralytic sequel of rabies had a marked effect on the degree of parasitism.

39 citations



Journal ArticleDOI
TL;DR: The results of a series of heat and chemical transformations of isolated Taenia taeniaeformis corpuscles and synthetic mixtures suggest that the major inorganic components of the native corpuscles are in the form of anAmorphous calcium phosphate and an amorphous MgCaCO2 complex.

35 citations


Journal ArticleDOI
TL;DR: Experimental evidence indicates that in both white mice and rats the immunogenic tissue phase of Hymenolepis nana elicits an inhibitory reaction to infectivity and growth of the related but nonimmunogenic H. diminuta .

33 citations


Journal ArticleDOI
TL;DR: A chemically defined medium containing 18 amino acids, 1 fatty acid, urea, Krebs cycle intermediates, purines, pyrimidines, vitamins of the B group and glucose as well as inorganic constituents supported the development of third stage larvae into adults and low but consistent levels of reproduction.

31 citations


Journal ArticleDOI
TL;DR: All of the enzymes of the Embden-Meyerhof pathway were demonstrated and evidence for the functioning of this pathway was obtained by measuring the degree of labelling of the carbon dioxide produced from variously labelled glucose-C 14, and by stepwise degradation of the acetic acid derived from glucose-1-C14.


Journal ArticleDOI
TL;DR: Nymphs, dissected 4 to 7 days after engorgement, seemed to be most satisfactory for the preparation of tick tissue cultures and some of the explant tissues commonly survived in vitro over 60 days and tissue movements and cell outgrowths were observed for 173 and 175 days respectively.


Journal ArticleDOI
TL;DR: It is considered that the differences regarding DDT penetration, excretion, and metabolism shown by nymphs as compared to males, may account at least partly for the higher tolerance to DDT exhibited bynymph T. infestans.

Journal ArticleDOI
TL;DR: Although there was an increase in numbers of coccidia in all other experimental groups, the increase was not significant in the caged control animals, and trichomonads in the stressed group showed significant increases over the field animals.

Journal ArticleDOI
TL;DR: With homogenate techniques the enzymes associated with the Krebs cycle were demonstrated in unembryonated eggs of Ascaris lumbricoides var.

Journal ArticleDOI
TL;DR: One of the major metabolites formed as a result of the fermentation of carbohydrate by Ascaris lumbricoides is a C6-volatile acid that has been isolated and characterized as α-methylvaleric acid on the basis of studies involving gas chromatography of the free acid, melting point of the p-bromphenacyl ester.

Journal ArticleDOI
TL;DR: Single and two-dimensional paper chromatograms were prepared of normal and de-coated embryonated eggs of Ascaris suum, vitelline membranes, egg fluid, and larvae to identify amino acids found in larvae and in normal and decoated embry onated eggs.

Journal ArticleDOI
TL;DR: It was found that morphological changes were minimal only when dialyzed perienteric fluid was used during the preparative procedure and it was suggested that the small number of cristae may be related to the essentially anaerobic type of metabolism characteristic for Ascaris.

Journal ArticleDOI
TL;DR: The incorporation of the C 14 uracil is markedly inhibited by 5-fluorouracil and largely depressed by unlabeled uridine or desoxyuridine, while the probable occurrence of uridineosphorylase and uridine phosphokinase is discussed.

Journal ArticleDOI
TL;DR: It is concluded that the basic annual ked population cycle can be affected by physiological or environmental stress such as pregnancy or undernourishment, as well as the role of the pituitary-adrenal system.

Journal ArticleDOI
TL;DR: Packing in mutant worms resembles the same process in normal material except for non-homologous pairing and formation of terminal loops on chromosomes 1, 2, and 3 and Translocations of short segments from chromosomes 3 and 5 to chromosome 1 seems a probable cause for the non-Homologous Pairing.

Journal ArticleDOI
TL;DR: It was concluded that resistance could not be produced immediately in lambs by infesting them with large numbers of keds but that the larger the infestation the sooner subsequent resistance developed.

Journal ArticleDOI
TL;DR: During the extended prophase of the germinative cells, growth occurs, nuclei and nucleoli enlarge and abundant cytoplasmic ribonucleic acid appears.

Journal ArticleDOI
TL;DR: The habitats and distributions of R. pipiens and A. aegypti plus experimental findings indicate that a life cycle involving the latter as intermediate host is probable, and ingestion is suggested as a probable method of infection of unparasitized frogs by infected mosquitoes.


Journal ArticleDOI
R.M. Michaels1, R.W. Treick1
TL;DR: The data have been interpreted as indicating that there is some sort of developmental cycle during the lag and early logarithmic phases of growth of T. vaginalis and that the inhibitor, by acting on an energy yielding mechanism, kills the cells by holding them in this early pattern.

Journal ArticleDOI
TL;DR: Eggs of Hydatigera taeniaeformis were tested in vitro for hatchability in an effort to predict in vivo results in laboratory animals and motility was determined by observing motility in the hatched oncospheres and in the ability of the onCospheres to take up vital stains.

Journal ArticleDOI
TL;DR: Infection of young adult male Holtzman rats with 4,000 Trichinella spiralis larvae initiated a moderate leucocytosis as early as the first post-infection day, and a rise in circulating eosinophiles which was first noted on the fifth post- Infection day persisted through post- infection days 6, 7, 8, 9 and 10.