Showing papers in "Hearing Research in 2016"

TL;DR: Deriving global estimates of the prevalence of tinnitus involves combining results from studies which are consistent in their definition and measurement of t Finnitus, survey methodology and in the reporting and analysis of the results.

TL;DR: Comorbidity is high and screening for and treatment of anxiety disorders is recommended in moderate to severe tinnitus, as, given the overlap in the structural and functional brain circuitries involved, theoretically, their management could improve (subjective) levels of tinnitis although further empirical research on this topic is required.

TL;DR: In this article, the authors discuss prevailing views of the structure and function of the strial cochlear-vascular unit (also referred to as the "intrastrial fluid-blood barrier") and discuss the disrupted homeostasis seen in a variety of hearing disorders.

TL;DR: It is revealed that the % volume of new bone as well as residual total spiral ganglion cell count are important factors influencing post-implant hearing performance.

TL;DR: Delayed loss of initially preserved hearing after cochlear implantation was not explained by additional post-implantation degeneration of hair cells or spiral ganglion neurons in this patient.

TL;DR: Data from a randomized controlled trial that involved testing the efficacy of "telephone tinnitus education" as intervention for bothersome tinnites was utilized to confirm sensitivity of the TFI along with its subscales.

TL;DR: For brain-computer interface (BCI) purposes, the linear discriminant analysis (LDA) and support vector machine (SVM) classifiers were applied to the four sound categories and the overall classification performance for the left hemisphere was higher than that for the right hemisphere.

TL;DR: Evidence from anatomical and functional MRI studies is reviewed to better understand the large-scale neural networks implicated in tinnitus habituation and severity, including that of the attention system suppressing the response from the amygdala and the use of alternate nodes of the limbic system when mediating emotion.

TL;DR: A putative model of the complex inter-relationships between tinnitus, cognition and confounding factors is proposed and this model provides a basis for hypothesis testing.

TL;DR: The TFI appears to cover multiple symptom domains, and to measure the construct of tinnitus with an excellent reliability in distinguishing between patients, and is less appropriate as a measure of change in this subgroup.

TL;DR: It is suggested that each cycle of the BCV or ACS stimulus causes fluid displacement which deflects the short, stiff, hair bundles of type I receptors at the striola and so triggers the phase-locked neural response of primary otolithic afferents.

TL;DR: It is argued that damage to the auditory system generates an initial tinnitus signal, consistent with previous research, and that limbic-system damage and resulting inefficiency of auditory-limbic interactions prevents proper compensation of the tinnitis signal.

TL;DR: DXMb eluting electrodes protected the cochlea against long term increases in hearing thresholds, loss of hair cells, damage to neural elements and increases in impedance and fibrosis that result from EIT-initiated damage.

TL;DR: The effects of auditory plasticity and deprivation on the emergence of binaural and spatial hearing are discussed along with evidence for reorganized processing from both behavioral and electrophysiological studies.

TL;DR: The results suggest that the HEI-OC1 might be a useful model to investigate biological responses associated with auditory cells, including auditory sensory cells, but a careful approach would be necessary at the time of evaluating drug effects.

TL;DR: The data suggest that the MEMR may be valuable in the early detection of cochlear neuropathy, particularly if the subset of ANFs with high thresholds and low spontaneous rates is preferentially lost.

TL;DR: Evidence that tinnitus originates in the cochlear nucleus (CN) is discussed, and mechanisms whereby hyperactivity may develop in the CN after peripheral auditory nerve damage are hypothesized.

TL;DR: This is the first study to report on LT results in a large number of UHL CI users, up to 10 years, and revealed that all patients still wear their CI seven days a week, eight (3-10) years after cochlear implantation.

TL;DR: This review details the growth and differentiation of the vestibular and auditory neuroepithelia, including synaptogenesis, the expression of stereocilia and kinocilia, and innervation of hair cells by afferent and efferent nerve fibres in the fetal human cochlea.

TL;DR: Data illustrate the feasibility of creating TM grafts with acoustic properties that reflect sound induced motion patterns of the human TM; furthermore, 3D printed grafts have mechanical properties that demonstrate increased resistance to deformation compared to temporalis fascia.

TL;DR: This review comprehensively outlines the cellular and molecular components positioned to regulate SGN afferent dendrite excitability, especially following glutamate release and indicates areas of future research to elucidate the contributions of the afferent signaling complex to both normal hearing and also hearing loss.

TL;DR: Functional neuroimaging can provide insight into the neurobiological factors that contribute to the variations in individual hearing outcomes following cochlear implantation, but there are important considerations to be made when using fNIRS to maximize the signal to noise ratio and to best identify meaningful cortical responses

TL;DR: It is speculated that suprathreshold ECAP measures, and also how they change as the IPG is increased, have the potential to be clinically applicable in human subjects, but further work is needed in order to determine the characteristics of these measures in humans who use cochlear implants.

TL;DR: With BC stimulation at the mastoid, the inner ear inertia dominated the excitation of the cochlea but inner ear compression and middle ear inertia were within 10 dB for almost the entire frequency range of 0.1-10 kHz.

TL;DR: Overall, the present results confirm that fNIRS can measure speech-evoked auditory responses in adults that are highly reliable at the group level, and indicate that signal processing to reduce physiological noise may substantially improve the reliability of fNirS measurements.

TL;DR: This morphometric analysis of the organ of Corti immunostained is shown to show that this SR-based morphological gradient is not fully established until postnatal day 28, well after other features, such as synaptic counts and efferent innervation density in both the inner and outer hair cell areas, appear fully mature.

TL;DR: It is suggested that effective tinnitus therapy could rely on modifying attention to the sensation rather than modifying the sensation itself, and its sensitivity, reliability, mechanism, and optimal implementation are incompletely understood.

TL;DR: This work reports here, for the first time, comprehensive transcriptome characterization of the adult human cochlea, ampulla, saccule and utricle of the vestibule obtained from patients without hearing abnormalities, and reveals evidence of tissue specific NMD in the hearing/balance system.

TL;DR: The results suggest that the immune and inflammatory responses are the essential responses to acoustic overstimulation in the cochlea.

TL;DR: Results suggest a contribution of temporal fine structure (TFS) to pure-tone detection thresholds and significant correlation with auditory thresholds and filter bandwidths indicated an impact of frequency selectivity on TFS usability in wide-band noise.