Journal•ISSN: 0736-0258
Journal of Clinical Neurophysiology
Lippincott Williams & Wilkins
About: Journal of Clinical Neurophysiology is an academic journal published by Lippincott Williams & Wilkins. The journal publishes majorly in the area(s): Electroencephalography & Epilepsy. It has an ISSN identifier of 0736-0258. Over the lifetime, 2487 publications have been published receiving 92137 citations.
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TL;DR: The P300 wave is a positive deflection in the human event-related potential that may represent the transfer of information to consciousness, a process that involves many different regions of the brain.
Abstract: SummaryThe P300 wave is a positive deflection in the human event-related potential. It is most commonly elicited in an “oddball” paradigm when a subject detects an occasional “target” stimulus in a regular train of standard stimuli. The P300 wave only occurs if the subject is actively engaged in the
1,768 citations
Journal Article•
897 citations
TL;DR: There is no uniformly accepted nomenclature for EEG patterns frequently encountered in critically ill patients such as periodic discharges, fluctuating rhythmic patterns, and combinatio.
Abstract: Continuous EEG Monitoring is becoming a commonly used tool in assessing brain function in critically ill patients. However, there is no uniformly accepted nomenclature for EEG patterns frequently encountered in these patients such as periodic discharges, fluctuating rhythmic patterns, and combinatio
865 citations
TL;DR: Structures involved in the descending analgesia systems, including the periaqueductal gray, locus ceruleus, and parabrachial area, nucleus raphe magnus, reticular formation, anterior pretectal nucleus, thalamus and cerebral cortex, and several components of the limbic system are described and the pathways and neurotransmitters utilized are mentioned.
Abstract: We review many of the recent findings concerning mechanisms and pathways for pain and its modulation, emphasizing sensitization and the modulation of nociceptors and of dorsal horn nociceptive neurons. We describe the organization of several ascending nociceptive pathways, including the spinothalami
847 citations
TL;DR: In addition, repetitive TMS (rTMS) can be applied in different paradigms to obtain a measure of various aspects of cortical excitability as mentioned in this paper, which can be useful not only as a research tool but also as a therapeutic intervention in neurology, psychiatry and neurorehabilitation.
Abstract: Transcranial magnetic stimulation (TMS) can be applied in different paradigms to obtain a measure of various aspects of cortical excitability. These different TMS paradigms provide information about different neurotransmitter systems, enhance our understanding about the pathophysiology of neuropsychiatric conditions, and in the future may be helpful as a guide for pharmacological interventions. In addition, repetitive TMS (rTMS) modulates cortical excitability beyond the duration of the rTMS trains themselves. Depending on rTMS parameters, a lasting inhibition or facilitation of cortical excitability can be induced. These effects can be demonstrated neurophysiologically or by combining rTMS with neuroimaging techniques. The effects do not remain limited to the cortical area directly targeted by rTMS, but affect a wider neural network transynaptically. Modulation of cortical excitability by rTMS may in the future be useful not only as a research tool but also as a therapeutic intervention in neurology, psychiatry, and neurorehabilitation.
772 citations