Showing papers in "Journal of Pediatric Orthopaedics in 2010"

Kingella kingae osteoarticular infections in young children: clinical features and contribution of a new specific real-time PCR assay to the diagnosis.

Abstract: BACKGROUNG: Kingella kingae is an emerging pathogen that may be recognized as the most common bacteria responsible for osteoarticular infections (OAI) in young children. However, its diagnosis remains a challenge and thus little evoked in infants, because K. kingae is a difficult germ to isolate on solid medium, and clinical signs are often mild. The main objective of this prospective study is to describe the clinical, biologic, and radiologic features of children with OAI caused by K. kingae. In addition, we describe the usage of a new specific real-time PCR assay in children under 4 years admitted for OAI with a probe that detects 2 independent gene targets from the K. kingae RTX toxin. PATIENTS AND METHODS: All children less than 4 years admitted in our institution between January 2007 and November 2009 for suspected OAI were enrolled in this prospective study (43 cases). Age, gender, clinical signs, duration of symptoms, bone or joint involved, imaging studies, and laboratory data, including bacterial investigations, full blood count, erythrocyte sedimentation rate, and serum C-reactive protein were collected for analysis. RESULTS: Identification of the microorganism was possible for 28 cases (65.1%) yielding K. kingae in 23 cases (82.1%). Mean age of children with K. kingae OAI was 19.6 months. Less than 15% of these patients were febrile during the admission, but 46% of them presented a history of fever-peak superior to 38.5 degrees C before admission. Thirty-nine percent of the children with K. kingae OAI had normal C-reactive protein; WBC was elevated in only 2 cases, whereas 21 patients had abnormal erythrocyte sedimentation rate, and 13 abnormal platelet counts. Direct Gram staining and classical isolation methods were negative for all cases subsequently detected as K. kingae OAI by specific real-time PCR. CONCLUSION: This study confirms that K. kingae is the major bacterial cause of OAI in children less than 4 years. The real-time PCR assay, specific to the K. kingae RTX toxin, provides interesting diagnostic performance when implemented in the routine microbiologic laboratory. Needless to say, a bigger cohort is required to adequately study this new qPCR assay, but the results so far seem promising. The most important additional finding is the mild-to-moderate clinical, radiologic, and biologic inflammatory response to K. kingae infection with the result that these children present few criteria evocative of OAI. LEVEL OF EVIDENCE: II.

Nerve injuries associated with pediatric supracondylar humeral fractures: a meta-analysis

Abstract: Background Supracondylar fractures of the humerus are the most common type of elbow fracture in children. Of all complications associated with supracondylar fractures, nerve injury ranks highest, although reports of the incidence of specific neurapraxia vary. This meta-analysis aims primarily to determine the risk of traumatic neurapraxia in extension-type supracondylar fractures as compared with that of flexion-type fractures; secondarily it aims to use subgroup analysis to assess the risk of iatrogenic neurapraxia induced by pin fixation. Methods A literature search identified studies that reported the incidence of nerve injury presenting with displaced supracondylar fractures of the humerus in children. Meta-analysis was subsequently performed to evaluate the risk of traumatic neurapraxia associated with supracondylar fractures. Subgroup analysis of included articles was additionally performed to assess the risk of iatrogenic neurapraxia associated with lateral-only or medial/lateral pin fixation. Results Data from 5148 patients with 5154 fractures were pooled for meta-analysis. Among these patients, traumatic neurapraxia occurred at a weighted event rate of 11.3%. Anterior interosseous nerve injury predominated in extension-type fractures, representing 34.1% of associated neurapraxias; meanwhile, ulnar neuropathy occurred most frequently in flexion-type injuries, representing 91.3% of associated neurapraxias. Nerve injury induced by lateral-only pinning occurred at a weighted event rate of 3.4%, while the introduction of a medial pin elicited neurapraxia at a weighted event rate of 4.1%. Lateral pinning carried increased risk of median neuropathy, whereas the use of a medial pin significantly increased the risk of ulnar nerve injury. Conclusions Of nerve injury associated with extension-type fractures, anterior interosseous neurapraxia ranks highest, whereas of flexion-type neuropathy, ulnar nerve injury predominates. We confirm that medial pinning carries the greater overall risk of nerve injury as compared with lateral-only pinning and that the ulnar nerve is at risk of injury in medially pinned patients. We additionally suggest that lateral pinning carries neurapraxic risk with respect to the median nerve. Level of evidence Level IV; Meta-analysis.

Eleven years experience in the operative management of pediatric forearm fractures.

Abstract: Background: There has been a trend toward operative management of pediatric diaphyseal forearm fractures (DFFx). We studied our experience with surgical management of these injuries to assess indications, frequency, outcome, and complications. Methods: One hundred forty-four consecutive children had surgical management of 149 DFFx over 11 years at our Level 1 pediatric trauma center. A chart/radiographic review established perioperative events, intraoperative findings, time-to-union, rangeof-motion, and complications. We developed the Children’s Hospital of Philadelphia Forearm Fracture Fixation Outcome Classification to assess postoperative outcomes. Results: Over 11 years, we treated 2297 DFFx; 155 of 2297 (6.7%) had surgical management. Six were lost to follow-up and excluded. A 7-fold increase in operative management was observed over the study period [2 of 143 (1.4%) vs. 28 of 270 (10.4%), P 10y of age, P=0.03]. Overall complication rate for IMN was 14.6% (15 of 103). Conclusions: Our center has operatively managed DFFx with increased frequency over the past decade. IMN had a complication rate of 14.6% and was frequently not ‘‘minimally invasive.’’ An open fracture site delayed healing. Compartment syndrome was more frequent when IMN was used the day of injury and older children had poorer outcomes and higher rates of delayed union. Level of Evidence: Level III, Retrospective Comparative Study.

Operative versus nonoperative treatment of midshaft clavicle fractures in adolescents.

Abstract: Background: Midshaft clavicle fractures in adolescents have traditionally been treated nonoperatively. Recent studies in the adult literature have shown a higher prevalence of symptomatic malunion, nonunion, and poor functional outcome after nonoperative treatment of displaced fractures. The purpose of this study was to compare operative versus nonoperative treatment of displaced clavicle fractures in adolescents. Materials and Methods: Adolescents who sustained closed midshaft clavicle fractures between 2000 and 2008 were identified in our institutional trauma registry. Medical records were reviewed for patient demographics, injury characteristics, treatment, and outcomes. Results: Forty-two consecutive patients (mean age 15.4y) with 43 closed midshaft clavicle fractures were identified. Twenty-five patients were treated nonoperatively with a sling or figure-of-8 brace. Seventeen patients were treated operatively with acute plate fixation for fractures displaced more than 2 centimeters. The average shortening at injury was 12.5mm in the nonoperative group and 27.5mm in the operative group (P=0.003). The mean time to radiographic union for displaced fractures was 8.7 weeks in the nonoperative group and 7.4 weeks in the operative group (P=0.02). There were no nonunions in either group. All complications in the operative group were related to local hardware prominence. The mean time to return to activities was 16 weeks in the nonoperative group and 12 weeks in the operative group. Symptomatic malunion, with a mean fracture shortening of 26mm, developed in 5 patients in the nonoperative group. Four of these patients elected corrective osteotomy with internal fixation and all went on to union with resolution of their symptoms. Conclusions: Plate fixation of displaced midshaft clavicle fracture reliably restores length and alignment. It resulted in shorter time to union with low complication rates. Symptomatic malunion in adolescents may be more common than earlier thought after significantly displaced fractures. Corrective osteotomy with plate fixation can restore clavicle anatomy and eliminate symptoms associated with malunion. Level of Evidence: Therapeutic level III.

Acetabular cartilage and labral damage observed during surgical hip dislocation for stable slipped capital femoral epiphysis.

Abstract: Background Surgical hip dislocation allows the surgeon full visualization of the proximal femur and acetabulum. It also makes it possible to directly observe the pathologic relationship between the proximal femur and acetabular rim with hip motion. The purpose of this study is to classify acetabular cartilage and labral damage that is present at the time of surgical hip dislocation for the treatment of symptomatic stable slipped capital femoral epiphysis (SCFE) hips. Methods A retrospective study was performed at 2 North American centers on patients with a stable SCFE who had a surgical hip dislocation for chronic symptoms. The severity of SCFE (slip angle) was measured as mild (0-30 degrees), moderate (30-60 degrees), and severe (60-90 degrees). The degree of acetabular and labral damage was classified in each patient according to the Beck classification used for femoroacetabular impingement. Results Thirty-nine hips in 36 patients that underwent open surgical dislocation for diagnosis of stable SCFE were included. The breakdown of the radiographic severity of the SCFE was 8 mild, 20 moderate, and 11 severe. Labral injury was observed in 34 of 39 hips. Using the Beck classification for labral injury, there were 21 type 1 injuries, 9 type 2 injuries, and 4 type 3 injuries. Cartilage injury was present in 33 of 39 hips. Using Beck classification for cartilage damage, there were 6 grade 0, 5 grade 1, 10 grade 2, 4 grade 3, 10 grade 4, and 4 grade 5 injuries. The average depth of cartilage damage was 5 mm (range, 2-10 mm). Conclusions In this study, significant chondromalacia and labral injury was observed in hips afflicted with SCFE. Surgical hip dislocation allowed direct confirmation of the impingement of the prominent metaphysis on the acetabular labrum and cartilage.

Growing rods for spinal deformity: characterizing consensus and variation in current use.

Abstract: Summary of Background Data: Growing rods are a commonly used form of growth guidance for patients with early onset scoliosis, but no studies exist to characterize their use among a large group of surgeons. Methods: A survey regarding growing rod use preferences and a case-based survey regarding early onset scoliosis were completed by an international group of surgeons. Two hundred and sixtyfive growing rod patients treated over 4.7 ± 2.1 years in the Growing Spine Study Group database were analyzed to characterize actual practice and compare it with the survey results. All patients had at least 2 years of treatment. Results: In the case-based survey, there was correlation (P = 0.04, r = 0.58) between increasing curve size and choice of growing rods over nonoperative treatment, rib-based distraction (vertically expandable prosthetic titanium rib), growth guidance (Shilla), and primary fusion. In practice, growing rods were used for most types of early onset spine deformity. Most surgeons stated that their indication for growing rod treatment was a curve over 60 degrees (10/13) in a patient younger than 8 to 10 years (14/17). In practice, mean curve at rod insertion was 73 ± 20 degrees and age was 6.0 ± 2.5 years. Other factors favoring growing rods included curve rigidity (8/17), brace intolerance (6/17) and syndromic diagnoses (2/17). In the database, idiopathic scoliosis represented < 50% of diagnoses. The most common preferred surgical lengthening interval was 6 months. However, in practice, lengthening actually occurred at a mean of 8.6 ± 5.1 months. In the database, the number of growing rod insertions per year (P = 0.02, r = 0.96) and percentage of surgeons using dual rods over single rods (P = 0.065, r = 0.93) increased over time. Insertion age (P = 0.075, r = ―0.87) and lengthening interval (P = 0.006, r = — 0.69) decreased as time progressed. The most common stated indication on the survey for final fusion was skeletal maturity (13/17), and 7/13 surgeons used Risser 3 or more. Indications to stop lengthening included complications such as infection or implant failure (14/17), curves progressing past 90 degrees (8/17), and failure to distract (6/13). The most common method of final fusion was replacement of implants with more intermediate anchors. Conclusions: Significant practice variation exists in growing rod treatment, but there is some consensus on indications for surgery including curve size, diagnosis and age, and lengthening intervals and final fusion methods. Mean curve size and lengthening interval are greater in practice than in surgeons' stated aims. In principle and in practice, most growing rods are used for curves over 60 degrees in patients under 10, in all diagnoses. This information may form a starting point as practice variation is studied.

Perfused, pulseless, and puzzling: a systematic review of vascular injuries in pediatric supracondylar humerus fractures and results of a POSNA questionnaire.

Abstract: BackgroundSupracondylar humerus fractures that present with a perfused, viable hand yet no pulse continue to be a source of controversy. The purpose of this study was to conduct a systematic review of the literature and perform a Pediatric Orthopaedic Society of North America (POSNA) opinion poll re

Iatrogenic ulnar nerve injury after the surgical treatment of displaced supracondylar fractures of the humerus: number needed to harm, a systematic review.

Abstract: Background Supracondylar fractures of the humerus are common pediatric elbow injuries. Most displaced or angulated fractures are treated by closed reduction and percutaneous pinning, with either a crossed pin or lateral pin configuration. The purpose of this study was to conduct a systematic review to determine if there is an increased risk of iatrogenic nerve injury associated with the crossed pin configuration. Methods Relevant articles were identified by searching electronic databases and hand searching-related journal and conference proceedings. Within each trial, the risk of iatrogenic ulnar nerve injury was calculated for each pinning technique. For studies comparing crossed versus lateral pinning, the resulting trial-based differences in risk estimates were pooled using a random effects meta-analysis. A number needed to harm was determined using the pooled risk difference. Results Thirty-two trials consisting of 2639 patients were used in the pooled analysis. The pooled risk difference of iatrogenic ulnar nerve injury is 0.035 (95% confidence interval, 0.014-0.056), with a higher incidence of injury in the crossed pinning group. The weighed number needed to harm for the crossed pinning is 28 (95% confidence interval, 17-71). Conclusions The results of this review suggest that there is an iatrogenic ulnar nerve injury for every 28 patients treated with the crossed pinning compared with the lateral pinning. Further research is necessary to ensure that the optimal pinning technique is chosen to treat these factors. Level of evidence Level III.

Risk factors for vascular repair and compartment syndrome in the pulseless supracondylar humerus fracture in children.

Abstract: Background The aims of this study were to determine how often fracture reduction alone restored pulses and vascular perfusion in displaced supracondylar humerus fractures with absent distal pulses on presentation, and whether any preoperative factors were associated with the need for vascular repair and vascular complications. Methods We reviewed 1255 supracondylar humerus fractures in children treated operatively over 12 years at one institution. We identified 33 patients who presented with displaced supracondylar humerus fractures and absent distal pulses. We reviewed the management and outcome of these injuries. Results Thirty-three (of 1255) patients presented with a pulseless supracondylar humerus fracture (2.6%). The patients were divided into 2 groups: those at presentation whose hand was well perfused (n=24) or poorly perfused (9). None (0 of 24) of the well-perfused patients underwent vascular repair; 3 had open reduction. Of the 21 well-perfused patients undergoing closed reduction and pinning, 11 (of 21) had a palpable pulse after surgery and 10 (of 21) remained pulseless but well perfused; all did well clinically. Of the 9 patients in the poorly perfused group, 4 underwent vascular repair, and compartment syndrome developed in 2 during the postoperative period. In just over half of patients with a poorly perfused hand (5 of 9), fracture reduction alone was the definitive treatment. Conclusions In the largest series of children with pulseless displaced supracondylar humerus fractures in the literature, we identify 2 distinct populations, with the perfusion status of the hand at time of presentation correlating significantly with the ultimate need for vascular repair. In patients presenting with a well-perfused hand, fracture reduction alone was sufficient treatment in all 24 (of 24) cases, and no patients developed compartment syndrome. Nearly half of these patients still had an absent palpable pulse but well-perfused hand after closed reduction, yet did well clinically. Patients presenting with a poorly perfused hand are at high risk for vascular repair and compartment syndrome.

Mechanical Failures of eight-PlateGuided Growth System for Temporary Hemiepiphysiodesis

Abstract: BackgroundFor decades, the Blount staple has been used to perform temporary hemiepiphysiodesis for angular deformity correction in children with open growth plates. Recently, the eight-PlateGuided Growth System (Orthofix, McKinney, TX) has gained popularity for use in this procedure. The eight-Plate

Achilles Tendon Length and Medial Gastrocnemius Architecture in Children With Cerebral Palsy and Equinus Gait

Abstract: Background: The aim of this study was to examine both the tendon and muscle components of the medial gastrocnemius muscle-tendon unit in children with cerebral palsy (CP) and equinus gait, with or without contracture. We also examined a small number of children who had undergone prior surgical lengthening of the triceps surae to address equinus contracture. Methods: Ultrasound was used to measure Achilles tendon length and muscle-tendon architectural parameters in children of ages 5 to 12 years. Muscle and tendon parameters were compared among 4 groups: Control group (N = 40 limbs from 21 typically developing children), Static Equinus group (N = 23 limbs from 15 children with CP and equinus contracture), Dynamic Equinus group (N = 12 limbs from 7 children with CP and equinus gait without contracture), and Prior Surgery group (N = 10 limbs from 6 children with CP who had prior gastrocnemius recession or tendo-achilles lengthening). The groups were compared using analysis of variance and Scheffe post hoc tests. Results: The CP groups had longer Achilles tendons and shorter muscle bellies than the Control group (P<0.001). Normalized tendon length was also longer in the Prior Surgery group compared with the Static Equinus group (P<0.001). The Prior Surgery group had larger pennation angles than the CP groups (Pr0.009) and tended to have shorter muscle fascicle lengths (Pr0.005 compared with Control and Static Equinus, P = 0.08 compared with Dynamic Equinus). Similar results were observed for pennation angles and normalized muscle fascicle lengths throughout the range of motion. Conclusions: Children with spastic CP and equinus gait have longer-than-normal Achilles tendons and shorter-than-normal muscle bellies. These characteristics are observed even in children with dynamic equinus, before contracture has developed. Surgery further lengthens the tendon, restoring dorsiflexion but not normal muscle-tendon architecture. These architectural

Decreased complications of pediatric femur fractures with a change in management.

Abstract: Background: Elastic intramedullary nails are commonly the preferred treatment option for operative stabilization of pediatric diaphyseal femur fractures. Increased complication rates have been reported in unstable fractures and older patients treated with TENs (titanium elastic nails). The reported complications have led to a change in management at our institution: limiting the use of TENs and using submuscular plating and trochanteric entry nails as alternatives. The purpose of this study is to analyze whether this change in management has improved outcomes defined by a decrease in complications between 2 time periods. Methods: This retrospective study compared 2 cohorts of femur fractures: those treated from January 2001 to January 2003 versus those treated from January 2003 to December 2006. Patient's age, weight, fracture type (stable or unstable), operative fixation technique, and complications were compared. Outcomes were measured by major or minor complications that occurred after operative treatment. Results: Period I consisted of 46 patients and Period II of 95 patients. There was a significant decrease in TEN use in unstable fractures in Period II versus Period I. Submuscular plating increased from 9% in Period I to 28% in Period II. All complications decreased from 52% in Period I to 23% in Period II. Major complications decreased from 22% to 5%, and minor complications decreased from 30% to 18%. Complications in unstable fractures decreased from 57% to 26% and in stable fractures from 48% to 22%. Conclusions: Outcomes of pediatric femur fractures are improved with limiting the use of TENs to stable fractures. Complications resulting from unstable femur fracture management have decreased with other methods of stabilization such as submuscular plating or trochanteric entry nails.

Complications of intrathecal baclofen pump therapy in pediatric patients.

Abstract: Background: The aim of this study was to investigate andevaluate complications of intrathecal baclofen (ITB) pumpimplantation and maintenance in children with cerebral palsy.Methods: We reviewed our entire consecutive series of pediatricpatients treated with ITB between 1997 and 2006 at ourhospital. There were 174 patients with a diagnosis of cerebralpalsy, 8 with mixed dystonia, 2 with athetosis, and 3 with puredystonia. During follow-up, 8 deaths occurred with no evidenceof pump or catheter malfunction in any way contributing to thecause of death. Acute infection within 60 days of the surgeryand late infection rates were calculated on the basis of numberof incidents and incidents/follow-up patient years, respectively.Independently, a blinded caregiver phone questionnaire wascompleted in 92 cases.Results: There were 316 surgical procedures; 161 were initial ITBpump implants at our institution. The average age at initialimplant was 12 years, with an average follow-up of 3 years, 2months. There were 80 planned replacement procedures (46battery expirations and 3 planned pump replacements duringposterior spinal fusion, 26 catheter replacements for posteriorspinal fusion, and 5 reinsertions). There were 78 procedures in57 patients related to complications, and the acute infection ratewas 4.0%. The probability of developing a late infection was1.0% per year of follow-up. On the basis of the follow-upquestionnaire, 81% of parents/caregivers were satisfied with thetreatment, and 87% would recommend ITB therapy.Conclusions: ITB therapy is a safe and effective treatment forsevere spasticity in the pediatric population, but does have a31% rate of complications requiring surgical management overa 3-year treatment period. Parents and caregivers have a highrate of satisfaction and most would recommend the treatment toothers.Key Words: cerebral palsy, intrathecal baclofen therapy,infection, complications(J Pediatr Orthop 2010;30:76–81)

Effect of high-frequency, low-magnitude vibration on bone and muscle in children with cerebral palsy.

Abstract: Background Children with cerebral palsy (CP) have decreased strength, low bone mass, and an increased propensity to fracture. High-frequency, low-magnitude vibration might provide a noninvasive, nonpharmacologic, home-based treatment for these musculoskeletal deficits. The purpose of this study was to examine the effects of this intervention on bone and muscle in children with CP. Methods Thirty-one children with CP ages 6 to 12 years (mean 9.4, SD 1.4) stood on a vibrating platform (30 Hz, 0.3 g peak acceleration) at home for 10 min/d for 6 months and on the floor without the platform for another 6 months. The order of vibration and standing was randomized, and outcomes were measured at 0, 6, and 12 months. The outcome measures included computed tomography measurements of vertebral cancellous bone density (CBD) and cross-sectional area, CBD of the proximal tibia, geometric properties of the tibial diaphysis, and dynamometer measurements of plantarflexor strength. They were assessed using mixed model linear regression and Pearson correlation. Results The main difference between vibration and standing was that there was a greater increase in the cortical bone properties (cortical bone area and moments of inertia) during the vibration period (all P's ≤ 0.03). There was no difference in cancellous bone or muscle between vibration and standing (all P's > 0.10) and no correlation between compliance and outcome (all r's 0.15). The results did not depend on the order of treatment (P > 0.43) and were similar for children in gross motor function classification system (GMFCS) 1 to 2 and GMFCS 3 to 4. Conclusions The primary benefit of the vibration intervention in children with CP was to the cortical bone in the appendicular skeleton. Increased cortical bone area and the structural (strength) properties could translate into a decreased risk of long bone fractures in some patients. More research is needed to corroborate these findings, to elucidate the mechanisms of the intervention, and to determine the most effective age and duration of the treatment. Level of evidence Level II, prospective randomized cross-over study.

Shoulder function after medial approach and derotational humeral osteotomy in patients with brachial plexus birth palsy.

Abstract: BACKGROUND The purpose of this study was to assess outcome after rotational humeral osteotomies, using a medial approach, in children with brachial plexus birth palsy. METHODS A retrospective review of children with brachial plexus birth palsy who underwent external rotational humeral osteotomies, using a medial approach, for the treatment of internal rotation contractures was performed. Presurgical and postsurgical range of motion, standard Mallet, and modified Mallet scores were recorded. The traditional Mallet score was modified to include a sixth subscale that further evaluated internal rotation. This was assessed by having the patients' attempts to place their palm flat on their naval. RESULTS Twenty-three children underwent external rotational humeral osteotomies. The mean rotational correction achieved during the procedure was 43.2+/-11.6 degrees (range: 20-70 degrees). The mean preoperative standard aggregate Mallet score was 13.8+/-2.8 and the mean postoperative score was 16.1+/-2.5 (P=0.002). When the additional internal rotation scale was added into the score, the mean preoperative aggregate score was 18.0+/-2.1 and the mean postoperative score was 19.5+/-2.8 (P=0.032). Further analysis revealed a statistically significant improvement (P<0.05) in external rotation, hand to neck, and hand to mouth functions. Internal rotation was decreased as represented by statistically significant decreases in hand to spine and hand to belly (P<0.05). CONCLUSIONS Rotational humeral osteotomies can be performed safely and effectively using a medial approach. These osteotomies significantly improve activities associated with external rotation. However, the degree of external rotation must be carefully balanced against the loss of internal rotation, which would impede midline function. The addition of a sixth subscale to the Mallet score that assesses hand to belly provides more clinically relevant information regarding midline function than hand to spine. LEVEL OF EVIDENCE This is a Level IV study.

Clubfoot classification: correlation with Ponseti cast treatment.

Abstract: Background Many different clubfoot classification systems have been proposed, but no single one is universally accepted. Two frequently cited systems, developed by Dimeglio/Bensahel and Catterall/Pirani, are often used for evaluation purposes in the treatment of idiopathic clubfoot. Our hypothesis was that the initial scores would be positively correlated with the number of casts required for clubfoot correction, indicating to us that the more severe score would require more casts, and therefore truly show the accuracy and usefulness of the scoring system. Methods From May 2000 to April 2008, 123 patients (185 feet) with idiopathic clubfeet were treated. All patients were below 60 days of age (mean 15.3 d, range: 2 to 57 d) at the time of their initial evaluation, and had not received prior clubfoot treatment. All cast placements were under the supervision of the same pediatric orthopedic surgeon. Initial correction was achieved in all patients. Results The mean number of casts required for correction was 5.1 (range: 2 to 8). On the basis of number of casts required, no significant differences were found in final total scores (Dimeglio/Bensahel P=0.14 and Catterall/Pirani P=0.44), indicating a similar level of correction for all feet. The Dimeglio/Bensahel and Catterall/Pirani classification systems were both similarly, poorly correlated with the number of casts needed [Spearman rank correlation coefficients (rs)=0.34 vs. 0.33]. The 2 components with the highest correlations were equinus (rs=0.39) and forefoot adduction (rs=0.35) for the Dimeglio/Bensahel system and coverage of the lateral head of the talus (rs=0.40) and rigid equinus (rs=0.39) for the Catterall/Pirani system. Conclusions When using the initial scores, both the Dimeglio/Bensahel and Catterall/Pirani classification systems had a low correlation with the number of Ponseti casts required. Analysis of the individual components revealed variability in the coefficients, with some having low-to-moderate correlation and others having none. There was no difference between the Dimeglio/Bensahel and Catterall/Pirani classification systems when measuring their correlation with the number of Ponseti casts required for clubfoot correction. An improved classification system is needed to predict the length of treatment and, ultimately, the risk of recurrence. Level of evidence Prognostic Level IV.

The unstable slipped capital femoral epiphysis: risk factors for osteonecrosis.

Abstract: Background The incidence of avascular necrosis (AVN) after unstable slipped capital femoral epiphysis (SCFE) varies widely in the literature (10% to 60%), and few studies have examined why certain unstable slips develop osteonecrosis whereas others do not. Our purpose was to determine risk factors for developing AVN after unstable SCFE. Methods We reviewed all unstable SCFEs treated primarily at our center. Medical records were reviewed to determine weight-percentile, age, length of prodromal symptoms, and time to treatment. Operative notes were used to classify treatment as either: (group 1) in situ screw fixation, (group 2) purposeful or inadvertent closed reduction and screw fixation, or (group 3) open reduction and internal fixation, and to determine whether or not the joint was decompressed during surgery. Preoperative radiographs were used to measure slip angle and percent translation. For group 2, these were compared with postoperative radiographs to calculate a Deltaslip angle and Deltatranslation. Student t tests and Fisher exact tests were used for statistical analysis. Results Of the 70 patients in our series, 14 developed AVN (20%). On the basis of treatment, 3 of 16 patients in group 1 (19%), 10 of 38 patients in group 2 (26%), and only 1 of 16 patients in group 3 (6%) developed AVN. Patients who developed osteonecrosis were significantly younger (11.67 y vs. 12.83 y, P=0.04) and had a significantly shorter duration of prodromal symptoms (17.5 d vs. 65.9 d, P=0.03) compared with those who did not develop AVN. None of the other factors were found to be significant. In a subgroup analysis looking solely at group 2 patients, those who developed AVN had a significantly higher initial slip angle compared with those who did not (62 degrees vs. 51 degrees, P=0.03). Conclusions In this, the largest reported series of unstable slips treated with internal fixation, AVN seemed more likely to develop in younger patients with a shorter duration of prodromal symptoms. Patients undergoing open reduction may have a lower incidence of AVN, but our limited power precludes definitive conclusions. Level of evidence Level IV (case series).

Arthroscopic management of osteochondritis dissecans of the capitellum: mid-term results in adolescent athletes.

Abstract: Background: The optimal treatment of osteochondritis dissecans(OCD) of the capitellum in adolescent athletes remains challeng-ing. The purpose of this study was to investigate the mid-termresults of arthroscopic treatment of OCD of the capitellum in aseries of adolescents.Methods: We identified 25 consecutive patients at our institutionthat underwent arthroscopic treatment for OCD of thecapitellum since 1999. Ten elbows were treated by arthroscopicdebridement and drilling alone, whereas 12 elbows requiredadditional mini-arthrotomies for bone grafting or the removal oflarge loose bodies after arthroscopy. The clinical charts andoperative reports of these patients were retrospectively reviewedfor relevant clinical information including age, sport, characterof symptoms, preoperative and postoperative range of motion,return to sport, and postoperative complications. Twenty-onepatients (22 elbows) were reached to determine their currentelbow function and athletic activity using the Single AssessmentNumerical Evaluation score.Results: The average age of the patients in our series was 13.1years. All patients participated in organized athletics thatinvolved the upper extremity and had undergone an averageof 10.2 months of nonoperative treatment before surgery. At amean follow-up of 48 months, the patients gained an average of17 degrees of extension and 10 degrees of flexion after surgery.Both the improvement in flexion and extension were statisticallysignificant compared with the preoperative range of motions(P=0.001, P=0.01). When patients were asked to rate theirelbow function from 0% to 100% using the Single AssessmentNumerical Evaluation score, the average rating was 87%.Eighteen of 21 patients (86%) returned to participate in theirsport at their preinjury level.Conclusion: Arthroscopic management of capitellar OCD in ado-lescent athletes results in significantly improved range of motionand a high rate of return to athletics. Accompanying arthrotomymay be required for large loose body removal or bone grafting.Level of Evidence: Level IV (case series).Key Words: elbow arthroscopy, osteochondritis dissecans,humeral capitellum(J Pediatr Orthop 2010;30:8–13)

Sequelae of Perthes disease: treatment with surgical hip dislocation and relative femoral neck lengthening.

Abstract: Background Sequelae of Perthes disease commonly manifests as complex hip pathomorphology including coxa magna, coxa brevis, and acetabular dysplasia. These abnormalities contribute to femoroacetabular impingement and early osteoarthritis. This report describes our experience with correction of the proximal femoral deformity associated with Perthes disease via surgical dislocation, osteochondroplasty (SDO), trochanteric advancement, and treatment of intra-articular chondrolabral injury.

Fixation of juvenile osteochondritis dissecans lesions of the knee using poly 96L/4D-lactide copolymer bioabsorbable implants.

Abstract: Background The fixation of juvenile osteochondritis dissecans (OCD) lesions has been described using metal implants, staples, bone pegs, and bioabsorbable implants. Bioabsorbable fixation has potential benefits including not requiring a second surgery for implant removal, no interference on postoperative magnetic resonance imaging (MRI) scans, and a potentially lower incidence of prominent hardware. The possible complications of bioabsorbable fixation include synovitis, loss of fixation owing to noncompressive properties, and sterile abscess formation. The results of bioabsorbable fixation of juvenile OCD lesions of the knee have not been well studied. The purpose of this study was to evaluate the efficacy and safety of a bioabsorbable copolymer fixation in the management of unstable OCD lesions of the knee in adolescents. Methods This is a retrospective case series of patients with unstable OCD lesions of the knee that were treated with poly 96L/4D-lactide copolymer bioabsorable implants. Information was gathered through 3 standardized and validated knee-function questionnaires, participants' medical records, plain films, MRIs, and pain level and satisfaction scale questionnaires. Results Twenty-four knees in 24 patients were evaluated. The mean age at the time of surgery was 14.4 years. The mean follow-up was 39.6 months. The mean International Knee Documentation Committee score at follow-up was 84.9, the mean Lysholm score was 88.0, and the mean Tegner score was 7.9. Plain films at an average of 19.2 months postoperatively revealed interval healing in 9 patients, no significant change in 1 patient, complete healing in 13 patients, and loose bodies with no interval healing in 1 patient. MRIs were obtained postoperatively in 17 knees, with a mean follow-up of 22.4 months. Interval healing was present in 16 of 17 MRIs, consistent with the plain film findings. Twenty-two of 24 patients had good-to-excellent outcomes. Conclusion Poly 96L/4D-lactide copolymer bioabsorable implants seem to be safe and effective for the management of unstable juvenile OCD lesions of the knee. They offer stability for the healing OCD lesions, with minimal reaction from degradation products.

Flexible intramedullary nail use in limb lengthening.

Abstract: Background: The aim of this study is to evaluate the influence of the external fixation associated with flexible intramedullary nailing (FIN) on the healing index (HI) in limb lengthening. Methods: We compared the healing index between 2 groups of children undergone the lengthening of upper and lower limbs carried out with the Ilizarov external fixator alone (group I, 194 cases of lengthening) or with the combination of the Ilizarov external fixator and intramedullary nailing (group II, 92 cases). Two nails of the diameter from 1.5 to 2.0 mm with the ray of curvature about 40 degrees to 50 degrees were used for the intramedullary nailing. Results: The HI was less in every subgroup of Group II compared with Group I. A significant difference was noted in congenital pathologies: monofocal monosegmental lengthening at the level of femur and forearm, bifocal lengthening of the tibia, polysegmental lengthening; and in acquired discrepancy: monofocal tibial lengthening, bifocal femoral lengthening, and the forearm lengthening. The reduction of HI was between 60% and 85% in congenital pathologies: monosegmental femur and forearm, bifocal femur and tibia lengthening; and in acquired discrepancy: femur, tibia, humerus and forearm monosegmental lengthening, humerus and tibia bifocal lengthening, and polysegmental in upper and lower limbs. This difference varies from 1.9 days/cm to 19.1 days/cm. That means that the duration of the external fixator was decreased of 20% to 33% of the number of days between the Group I and the Group II. Maximum diminution of HI was noted for monofocal acquired forearm cases (51.3%) and bifocal acquired femoral lengthening cases which (59.9%). Conclusions: The flexible intramedullary nailing allows adding multiple advantages to the method of limb lengthening with the external fixator. Correctly applied the FIN indeed respects the bone biology that is essential during the limb lengthening. The major effect of application of the combination of Ilizarov frame fixation with FIN is a significant decrease of duration of the external osteosynthesis. Level of Evidence: II.

Medial and lateral pin versus lateral-entry pin fixation for Type 3 supracondylar fractures in children: a prospective, surgeon-randomized study.

Abstract: Background The purpose of this study is to compare the efficacy of medial and lateral (crossed pin) and lateral-entry pin techniques for Gartland Type 3 supracondylar humerus fractures in children. Methods Six pediatric orthopaedists were divided into the 2 treatment groups (medial and lateral pins or lateral only pins) based on pre-study pinning technique preferences. Patients were randomized into 1 of the 2 pinning technique treatment groups based on which attending was on call at the time of patient presentation. One hundred and four patients met inclusion criteria. Forty-seven patients underwent lateral-entry pinning and 57 underwent crossed pinning. The 2 groups were similar with respect to age, sex, preoperative neurovascular injury, direction of fracture displacement, and timing of surgery. Outcome parameters measured included radiographic maintenance of reduction, iatrogenic neurovascular complications, and rate of infection. All radiographic measurements, and interobserver reliability, were determined by a 3 physician panel. Results The results of the interobserver reliability data showed a strong correlation and this data allowed 95% confidence that a change in Baumann's angle of more than 6 degrees and humerocapitellar angle of more than 10 degrees was significant. The lateral-entry patients experienced a median absolute change of Baumann's angle of 3.7 degrees with 12 patients having greater than 6 degrees loss of reduction; whereas those in the medial and lateral-pin group saw a median change of 2.9 degrees with 10 patients having greater than 6 degrees loss of reduction. In terms of the humerocapitellar angle, the lateral-entry patients experienced a median absolute change of 4.8 degrees with 11 patients having greater than 10 degrees loss of reduction; whereas those in the medial and lateral-pin groups saw a median change of 5.1 degrees with 17 patients having greater than 10 degrees loss of reduction. There was no significant difference in infection rate between the 2 groups but 2 cases of iatrogenic neurovascular injury occurred in patients who had a medial pin placed. Conclusions We found no statistical difference in the radiographic outcomes between lateral-entry and medial and lateral-pin techniques for the management of Type 3 supracondylar fractures in children when evaluated in this prospective and surgeon-randomized trial, but 2 cases of iatrogenic injury to the ulnar nerve occurred with medially placed pins. Level of evidence Level 2.

The pediatric LCP hip plate for fixation of proximal femoral osteotomy in cerebral palsy and severe osteoporosis.

Abstract: Hip dislocation or subluxation together with poor nutrition, reduced weight bearing, and osteoporosis is a frequent condition in severe cerebral palsy (CP). Severe osteoporosis may cause difficulties in fixing a proximal femoral osteotomy with a conventional blade plate. The Pediatric locking compression plate (LCP) Hip Plate system offers better grip and more stable fixation.

Outcomes of extra-articular, intra-epiphyseal drilling for osteochondritis dissecans of the knee.

Abstract: BACKGROUND When conservative management fails to heal femoral condyle osteochondritis dissecans (OCD) lesions in a child, then drilling of the subchondral plate below the lesion to stimulate healing may be beneficial. This study reviews the outcomes of extra-articular, intraepiphyseal drilling of OCD lesions of the knee with intact articular cartilage. METHODS Over an 8-year period, all children, who failed at least 6 months of nonoperative management, underwent arthroscopic knee surgery and extra-articular, intra-epiphyseal drilling for their symptomatic, nondisplaced femoral condyle OCD lesions. The clinical and radiographic outcomes were evaluated by using demographics, preoperative size of the lesion, intraoperative concomitant pathology, complications, postoperative range of motion, return to activities, radiographic progression of healing, and subsequent operative procedures. RESULTS In all 59 children, the mean time to return to activities was 2.8 months (1.3 to 13.1 mo) and the mean percentage of radiographic healing was 98.2% (79% to 100%) at final follow-up. Forty-four (75%) of the OCD lesions were successfully treated to 100% radiographic healing with an average time for healing of 11.9 months (1.3 to 47.3 mo). The large lesions took significantly longer to heal than the small lesions, 15.3 months versus 8.8 months (P=0.032), and the percentage of radiographic healing at final follow-up approached significance with large (>3.2 cm²) lesions attaining a mean of 96.9% (standard deviation 6.4%) versus small lesions (<3.2 cm²) with a mean of 99.4% (standard deviation 2.1%, P=0.083). No operative complications were observed. CONCLUSIONS Extra-articular, intraepiphyseal drilling of OCD lesions produced excellent results over the historical controls using intra-articular drilling for those patients who failed initial conservative management. This technique allows for more drill holes to be placed perpendicular to the OCD lesions, especially the posterior lesions that may have limited intra-articular access. Furthermore, this technique avoids intraoperative damage to the overlying intact articular cartilage and promotes osseous healing by fenestration of the sclerotic rim surrounding the OCD lesion. LEVEL OF INCIDENCE Prognostic study, Level IV (retrospective study).

Gait, hip strength and functional outcomes after a Ganz periacetabular osteotomy for adolescent hip dysplasia.

Abstract: BackgroundThe Ganz (Bernese) periacetabular osteotomy was first described for the treatment of adult patients with hip dysplasia; however, it has also been used for adolescent patients. Its effectiveness in improving patients in the short term has not been fully established and no studies, to our kn

The effects of surgical delay on the outcome of pediatric supracondylar humeral fractures

Abstract: BackgroundOccasionally, the treatment of a pediatric supracondylar humeral fracture is delayed owing to lack of an available treating physician, necessitating transfer of the child, or delay in availability of an operating room. The purpose of this study is to prospectively evaluate whether delayed

Increased risk of Blount disease in obese children and adolescents with vitamin D deficiency.

Abstract: BACKGROUND Poor dietary habits and decreased outdoor activity has led to an epidemic of obese children and vitamin D deficiency. The lack of vitamin D alters bone development and mineralization by diminishing physiological levels of calcium and phosphorus. Given vitamin D's role in bone and growth plate mineralization and regulation, we hypothesized that vitamin D deficiency would lead to higher rates of fractures, slipped capital femoral epiphysis (SCFE), and Blount disease in obese youth. METHODS A retrospective review was performed at the obesity clinic using the obesity database (890 patients). Data obtained included body mass index (BMI), vitamin D levels (25-vitamin D), history of fractures, Blount disease, and/or SCFE. The chart review identified 2 populations of obese patients, those with vitamin D deficiency, 16 ng/mL (692 patients). Fisher exact, χ², and 2-sample t tests along with logistic regression were used for statistical analysis. A P value ≤0.05 was considered statistically significant. RESULTS Blount disease was found to have a statistically significant (P<0.05) positive association with patient's sex, BMI, and vitamin D level. Specifically, males were 8.16 times more likely than females to be observed with Blount disease (P=0.01). Patients with very low vitamin D levels were 7.33 times more likely to have Blount disease than patients with higher levels (P=0.002). Each whole number increase in BMI increases the likelihood of Blount disease by 3% (P=0.01). There was no association between increased number of fractures or SCFE with vitamin D deficiency in these obese patients. CONCLUSION As our findings indicate, BMI and vitamin D levels have a strong association with Blount disease, which may be especially important among males. Ours is the first study to show a relationship between vitamin D deficiency and Blount disease, but further prospective studies are needed with larger numbers to confirm this independent association of vitamin D deficiency with Blount disease. LEVEL OF EVIDENCE Level III retrospective study.

Varus derotation osteotomy for the treatment of hip subluxation and dislocation in GMFCS level III to V patients with unilateral hip involvement. Follow-up at skeletal maturity.

Abstract: PurposeHip displacement is common in children with cerebral palsy (CP) The risk of hip displacement is related to gross motor function level as graded with the Gross Motor Function Classification System (GMFCS) Most clinicians agree that surgical treatment is indicated for progressive hip subluxat

Operating room traffic: is there any role of monitoring it?

Abstract: BackgroundOperating room (OR) human traffic has been implicated as a cause of surgical site infection. We first observed the normal human traffic pattern in our Pediatric Orthopedic ORs, and then examined the effect of surveillance on that traffic pattern.MethodsThis study consisted of 2 phases: pha

Outcome of In Situ Pinning in Patients With Unstable Slipped Capital Femoral Epiphysis: Assessment of Risk Factors Associated With Avascular Necrosis

Abstract: Introduction: Avascular necrosis (AVN) is a devastating complication following treatment of unstable slipped capital femoral epiphysis (SCFE). The advent of newer methods such as open reduction and surgical dislocation of the hip has increased the debate on the optimal method of treatment. However, the risk or predisposing factors for AVN remain unclear. We aimed to assess the outcome of in situ fixation and the risk factors associated with AVN. Methods: We retrospectively reviewed the records of 27 patients (27 hips) with unstable SCFE out of the 280 children managed for SCFE from 1995 to 2006. The mean age in years of the patients at surgery was 12.2 ± 1.58, and our sample comprised 70.4% males, and 29.6% females, with a mean follow-up of 3.1 ± 1.9 years. Univariable and multivariable binomial regression models were used to assess factors predisposing to AVN. Results: AVN occurred in 22.2% (6/27) of the children with unstable SCFE. After adjustment for age, race, and time to surgery, sex and preoperative slip angle were the only 2 significant factors related to an increased risk of AVN, risk ratio (RR) = 4.15, 95% confidence interval = 1.00-17.19, P = 0.05 and RR = 1.04, 95% confidence interval = 1.00-1.07, P = 0.03, respectively. Female children constitute a high-risk group for AVN in this subgroup. Conclusions: AVN is still prevalent among patients with unstable SCFE who underwent in situ pinning. Female sex and slip magnitude are potential predisposing factors for developing AVN.