Showing papers in "Journal of Pharmacy Research in 2013"

TL;DR: The search for non-toxic antioxidants have intensified in the recent years as they neutralize the effects of ROS and thus help in preventing diseases.

TL;DR: The Invertase from baker's yeast was purified by concentrating the crude extract with ammonium sulphate, dialyzed using sample buffer and followed by centrifugation, and the resultant supernatant was applied on DEAE-cellulose column equilibrated with Tris buffer.

TL;DR: The nanoparticles synthesized from the aqueous leaf extract of Morinda pubescens by reducing silver nitrate are found to possess high antioxidant capacity and thus can be used as potential radical scavengers against deleterious damages caused by the free radicals.

TL;DR: The AgNPs produced by endophytic fungi displayed considerable antibacterial activity and hence this study would prove to provide novel antimicrobial agents synthesized in a facile way.

TL;DR: The present review unearths marine microbial flora in synthesis of nanoparticles, a rapidly developing research area in nanotechnology across the globe, which has untapped potential in marine microorganisms as nanofactories to fabricate nanoparticles.

TL;DR: Through the article the technology involved, need and application of nanobiotechnology based tissue engineering will be understood.

TL;DR: In this article, a photo-irradiation-based method was developed for the synthesis of silver nanoparticles against Staphylococcus aureus (MRSA) infection using Streptomyces coelicolor pigment.

TL;DR: Amorphous solid dispersions are one of the most promising strategies to improve the oral bioavailability of sparingly water-soluble drugs as discussed by the authors, and they have been shown to improve drug wettability and bioavailability significantly.

TL;DR: In this paper, the influence of location, seasonal variation and solvent system in production of phytochemicals and antioxidants from ginkgo leaves was determined by a factorial analysis.

TL;DR: In this article, the authors developed and validated an efficient and effective RP-HPLC method for quantification of eugenol from commercial marketed formulations Separation was carried out on a cosmosil C18 column, mobile phase composition was methanol: distilled water (60:40, v/v) at flow rate of 1 mL/min Detection was conducted at 215nm using a photodiode array detector (PDA) Commercial Ayurvedic formulations such as Caturjata Churna, Lavangadi Vati, Jatiphaladi Churn

TL;DR: Antimicrobial studies suggest that essential oil loaded PLGA nanoparticles could be useful in biomedical and food applications.

TL;DR: The findings of studies on the aforementioned properties of the plant in detail and 68 alkaloids isolated from various parts of plant are discussed to justify its widespread use in the treatment of a variety of diseases and suggests future lines of research.

TL;DR: In this paper, the authors investigated the use of liquisolid technique in improving the dissolution of candesartan cilexetil in a solid dosage form, which is an angiotensin-II receptor antagonist used for the treatment of hypertension.

TL;DR: In this article, a sustained release nanoparticles has been designed to maintain constant level of a drug in the patient's blood stream, which can increase patient compliance by reducing the number of dosage and incidence of side effects.

TL;DR: In this paper, the leaves of Pteridium aquilinum collected from Dibrugarh were analysed for phytochemical constituents, antioxidant activity and antimicrobial property.

TL;DR: This work states that there is a need to use the genetic techniques to improve crops over the recent decades to feed the growing population and to produce more desirable products.

TL;DR: There is an urgent need to record and preserve all information on plants used by different ethnic/tribal communities for various purposes before it is completely lost to strengthen the documentation of ethnic drugs.

TL;DR: Ageratum conyzoides L. and Mikania cordifolia L were evaluated using acetic acid induced writhing in mice and for investigating the antioxidant activity, four complementary test methods namely DPPH free radical scavenging assay, reducing power assay, ferrous ion chelating ability assay and total phenolic content determination were carried out.

TL;DR: In this paper, the authors formulated aqueous nanodispersion of aceclofenac NLC by using modified hot sonication method and to prepare NLC-based gel for topical delivery of ace-cloffenac.

TL;DR: In this paper, the authors developed a sustain release metformin hydrochloride nanoparticulate system and studied the effect of different viscosity grade ethylcellulose polymers on in-vitro characteristics of obtained nanoparticles.

TL;DR: The findings indicated the anti-inflammatory evaluation of methanolic leaf extract of A. vulgaris has shown significant anti- inflammatory activity at 200 and 400 mg/kg, whereas 400 mg/kg dose shown significant results when compared with control.

TL;DR: The presence of unusual combination these phytochemicals in T. dioica mayserve as a potential source of useful drugs in the near future.

TL;DR: The toxic effects of paracetamol were significantly controlled in the extract treated groups which was manifested by the restoration of serum biochemical parameters to near normal levels.

TL;DR: It is possible that this herb is beneficial not only on glycemic control, but also on potential systemic complications of type 2 diabetes mellitus.

TL;DR: In this paper, a modified solvent emulsification diffusion technique was used to produce Haloperidol loaded solid lipid nanoparticles and a 3-factor, 3-level Box-Behnken design was applied to study the effect of independent variables (factors) i.e. drug to lipid ratio (A), surfactant concentration (B) and stirring speed (C) on dependent variables (responses), i. e. particles size, entrapment efficiency, and drug loading (Y 3).

TL;DR: In this paper, an HPLC method for the simultaneous estimation of curcumin and piperine with adequate separation was developed and validated using Eudragit E 100 nanoparticles.

TL;DR: The most important risk factors and morphological changes in the cartilage and bone during the development of OA are described.

TL;DR: In this paper, Carum carvi powder was extracted using water, 50% alcohol and 1:1 mixture of methanol and acetone and the yield was found to be 8.76, 12.63 and 50.20 mg/g, respectively.

TL;DR: In this article, a high performance liquid chromatography method was used to evaluate the chemical stability using R. kordesii extract as marker at 5, 25 and 45°C for 3-4 months.

TL;DR: In this paper, a chitosan/silvernan composite was synthesized by using UV-Vis, FTIR, XRD and HRSEM analysis and the SEM images illustrate the presence of embedded silver nanoparticles (20-50nm) throughout the films.