Showing papers in "Pharmacological Research Communications in 1988"

TL;DR: It is concluded that the non-flavone fraction of EGB carries the antihypoxidotic activity and metabolic effects are suggested to cause this activity.

TL;DR: How this book will influence you to do better future will relate to how the readers will get the lessons that are coming.

TL;DR: Ethanolic extract of propolis (EEP) is capable of increasing the number of plaque-forming cells in spleen cell population of immunized male BALB/c mice, demonstrating their ability to produce antibodies.

TL;DR: From the findings it derives that albumin may have two possibilities of scavenging peroxides: PLA and the SH group.

TL;DR: The fruit extract of Momordica charantia Linn was studied in Charles Foster rats of both sexes in respect of its dose-response hypoglycemia and at maximal effective dose, its influence on the development of diabetic cataract.

TL;DR: The pharmacological properties of essential oils obtained from two varieties of Anthemis nobilis, named "white-headed" or double flowered and "yellow-headed", present considerable morphological differences and yield essential oils with different composition.

TL;DR: The findings indicate that the frequency-dependent purine release from cultured glial cells is linked to ionic mechanisms, which calcium and potassium are mainly involved in.

TL;DR: The anti-inflammatory activity of three benzo-pyrones with prevalent lipooxigenase-inhibitory activity was studied using the Croton oil ear test in mice, in comparison with nordihydroguaieretic acid (NDGA) and indomethacin.

TL;DR: Esculetin determined a reduction in oedema and granulocyte infiltration in the Croton oil ear test in vivo and has an anti-inflammatory and analgesic effect.

TL;DR: Propionyl-L-Carnitine significantly improved mitochondrial function, but failed to reduce malondialdehyde formation and ferrous ions induced an increase of malondialsdehyde Formation and a reduction of mitochondrial oxygen consuming and calcium transporting capacities.

TL;DR: Five fractions of an aqueous extract obtained from the roots of Echinacea angustifolia were separated and high-molecular weight polysaccharides were proposed as the anti-inflammatory principles of the plant.

TL;DR: The results suggest that in the rat colon isoprenaline interacts with different beta-receptor subclasses, whereas the new gut-specific compounds such as SR 58306A inhibit colonic motility by selectively stimulating atypical beta-adrenoceptors.

TL;DR: The relaxant effect of resveratrol on guinea pig isolated trachea was not due to interactions with histaminergic or cholinergic systems, but appeared to be influenced by beta-blockers, indomethacin and mepacrine.

TL;DR: Results evidence either an important role for PAF in guinea pig anaphylaxis or a wider spectrum of activity for BN-52021 in a dose-dependent manner, particularly that of histamine.

TL;DR: Four calcium channel blockers were tested from the point of view of their influence on enzymic lipid oxidation and on generation of superoxide anions and all the compounds were found to be antioxidants as tested by the inhibition of NADPH-stimulated malonaldehyde formation from lipids.

TL;DR: It was observed that when entrapped into liposomes, ATP greatly increased the number of ischemic episodes tolerated before brain electrical silence and death appeared, which could open new possibilities in brain antihypoxic protection.

TL;DR: For allyl alcohol, 1,1-dichloroethylene, dimethylnitrosamine, thioacetamide, bromobenzene and paracetamol no hepatoprotection was achieved with DFO indicating that lipid peroxidation is not involved as a primary mechanism of toxicity.

TL;DR: Results are according to the proposition that the contractile state depression is related to the sympathetic hyperactivity, as suggested by the IPA pre-treated group and because the animals with isolated pressure overload showed a better contractile performance when compared to their uninephrectomized controls.

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TL;DR: The vasopressin releasing effect of eledoisin is apparently related to central angiotensin release in a specific neuronal pathway subserving vasoppressin release, which is not secondary to inhibition by tachykinins of the brain mechanisms for angiotENSin-induced drinking, but is probably expression of direct activation of specific tachyKinin receptors controlling vasopressing release.

TL;DR: Algae extracts from the Gulf of Trieste were assayed in vitro against human tumour established cell line (KB) for cytostatic activity, in particular Dictyopteris membranacea (Stackh.) Batt.

TL;DR: The highest concentration of isovitexin occurred between pre-flowering and flowering stages and the greatest accumulation of flavonoids took place in the leaves.