Maged Younes

TL;DR: It was concluded that the TEF concept is still the most plausible and feasible approach for risk assessment of halogenated aromatic hydrocarbons with dioxinlike properties.

TL;DR: In this article, the authors present a data base containing information relevant to the setting of Toxic Equivalency Factors (TEFs), and, based on the available information, to assess the relative potencies and to derive consensus TEFs for PCDDs, PCDFs and dioxin-like PCBs.

TL;DR: The participants discussed the health risks for infants, cancer and non-cancer endpoints in humans and animals, mechanistic aspects, kinetic behaviour, modelling, exposure, and the applicability of the toxic equivalency (TEQ) concept, which focused on the most sensitive effects seen at low doses in animal studies.

TL;DR: A conceptual framework was developed, based on the general principles involved in considering the chemical induction of a specific tumor in animals, based partly on the Bradford Hill criteria for causality as modified by Faustman et al. (1997) for developmental toxicity.

TL;DR: In this article, a definition of TVOC referring to a specified range of VOCs and a method for the measurement of this TVOC entity is proposed, within the specified range, the measured concentrations of identified VOC (including 64 target compounds) are summed up, concentrations of non-identified compounds in toluene equivalents are added and, together with the identifiedVOCs, they give the TVOC value.