Showing papers in "Postgraduate Medicine in 1969"
TL;DR: The acute arthritis in gout and in pseudogout is associated with microcrystals of monosodium urate and calcium pyrophosphate dihydrate, respectively.
Abstract: The acute arthritis in gout and in pseudogout is associated with microcrystals of monosodium urate and calcium pyrophosphate dihydrate, respectively. These conditions share certain clinical feature...
53 citations
TL;DR: A comparative study of 98 cases of myeloid metaplasia and 93 cases of chronic granulocytic leukemia suggests a common pathogenetic mechanism and the laboratory procedures most helpful in differentiation were leukocyte alkaline phosphatase determinations and cytogenetic studies.
Abstract: A comparative study of 98 cases of myeloid metaplasia and 93 cases of chronic granulocytic leukemia suggests a common pathogenetic mechanism. The laboratory procedures most helpful in differentiation were leukocyte alkaline phosphatase determinations and cytogenetic studies. Acute leukemia occurring in four cases of myeloid metaplasia supports the theory that polycythemia vera, myeloid metaplasia, and chronic and acute granulocytic leukemia constitute a spectrum of myeloproliferative disorders.
51 citations
TL;DR: Although ankylosing spondylitis is a common disease, it often goes unrecognized for many years and not much of the deformity that may otherwise result is known.
Abstract: Although ankylosing spondylitis is a common disease, it often goes unrecognized for many years. Early diagnosis, education of the patient, and adherence to a carefully planned program of treatment will prevent much of the deformity that may otherwise result. Employability and economic independence can be maintained by the vast majority of patients.
17 citations
TL;DR: In this paper, the authors argue that young people who approach doctors for assistance must be treated as individuals who are in a difficult time of life when a young patient needs contraceptive assistance the doctor should not refuse merely because the patient is young or lacks parental consent and there has been no single instance of legal action against a doctor who gave contraceptive assistance where parental consent was lacking.
Abstract: Unwanted pregnancy is a disease with consequences that affect every level of society Illegitimacy is rising to the point where it is a major social problem Findings of the National Center for Health Statistics show that in the 1940-1965 period illegitimacy tripled More than 40% of unwed mothers are teenagers It is clear that young people who approach doctors for assistance must be treated as individuals who are in a difficult time of life When a young patient needs contraceptive assistance the doctor should not refuse merely because the patient is young or lacks parental consent So far there has been no single instance of legal action against a doctor who gave contraceptive assistance where parental consent was lacking
17 citations
TL;DR: The case reported here, of a boy born with typical skin changes and everted lids, responded to conservative treatment and is reported to have responded to conventional treatment.
Abstract: Collodion skin disease usually affects premature infants. They have tight, thin skin like parchment and hold their faces immobile. Their eyelids are either sealed tight or everted. The case reported here, of a boy born with typical skin changes and everted lids, responded to conservative treatment.
17 citations
TL;DR: All that is needed to correct massive rectal prolapse is a restraining sling placed around the abnormally mobile rectum and fixed to the sacrum, with minimal mortality and morbidity.
Abstract: Massive rectal prolapse causes fecal incontinence, with formidable psychologic trauma. Many such patients avoid all social contacts. All that is needed to correct this condition is a restraining sling placed around the abnormally mobile rectum and fixed to the sacrum. This simple operation offers the best results, with minimal mortality and morbidity.
14 citations
TL;DR: These cases point up the need for suspicion of actinomycosis in patients with pulmonary, cervicofacial or abdominal disease accompanied by a draining sinus, and the therapeutic agent of choice is penicillin G.
Abstract: Two cases of thoracic actinomycosis are described. In one, pericarditis was an unusual feature. These cases point up the need for suspicion of actinomycosis in patients with pulmonary, cervicofacia...
12 citations
TL;DR: The plasma concentration of growth hormone reaches a peak within one or two hours after the onset of sleep, and during most of the day the levels may be almost unmeasurable.
Abstract: The plasma concentration of growth hormone reaches a peak within one or two hours after the onset of sleep. During most of the day the levels may be almost unmeasurable. The conditions under which plasma is obtained for testing assume great significance in view of the unusual normal secretory pattern. Some applications and limitations of growth hormone assays are considered.
12 citations
TL;DR: A high proportion of patients with myotonia dystrophica, probably about 50 percent, have cholelithiasis, and in addition many have other visceral abnormalities.
Abstract: A high proportion of patients with myotonia dystrophica, probably about 50 percent, have cholelithiasis. In addition many have other visceral abnormalities. Tracheal aspiration and pneumonia are particular threats to patients undergoing surgery.
12 citations
TL;DR: Electrode technology has developed a practical, rapid method using a specific calcium electrode for measuring ionized calcium that could be potentially useful in many diseases, including sarcoid, metastatic carcinoma, bone dysplasia and cardiac dysrhythmias.
Abstract: Measurements of serum ionized calcium could be potentially useful in many diseases, including sarcoid, metastatic carcinoma, bone dysplasia and cardiac dysrhythmias. Electrode technology has developed a practical, rapid method using a specific calcium electrode for measuring ionized calcium.
TL;DR: Fourteen patients with septic arthritis superimposed on a variety of conditions have been reported, and physical examination of joints produces diagnostic suspicion, and joint paracentesis produces diagnosis suspicion.
Abstract: Fourteen patients with septic arthritis superimposed on a variety of conditions have been reported. Physical examination of joints produces diagnostic suspicion, and joint paracentesis produces dia...
[...]
TL;DR: For the first time, an official technical mission from the United States has obtained firsthand information on the health of the Biafran population and confirms that the extent of the caloric and protein malnutrition and the scope of outright famine make the Nigeria-Biafra conflict one of the great nutritional disasters of modern times.
Abstract: For the first time, an official technical mission from the United States has obtained firsthand information on the health of the Biafran population. Their reports confirm that the extent of the caloric and protein malnutrition and the scope of outright famine make the Nigeria-Biafra conflict one of the great nutritional disasters of modern times.
TL;DR: Magnesium has long been considered a mysterious cation of relative unimportance in clinical medicine, but atomic absorption methods have made possible reliable determinations of magnesium in body fluids.
Abstract: Magnesium has long been considered a mysterious cation of relative unimportance in clinical medicine. Atomic absorption methods have made possible reliable determinations of magnesium in body fluids. Its importance in growth and development is unquestioned, although little is known about its homeostatic regulation or role in disease states.
TL;DR: Wider and earlier use of synovectomy in all surgically accessible joints will probably be the greatest contribution of orthopedic surgery in the treatment of rheumatoid arthritis.
Abstract: When adequate medical management of the rheumatoid arthritic patient proves ineffective, surgery is often indicated. The most promising surgical procedure is synovectomy. Wider and earlier use of synovectomy in all surgically accessible joints will probably be the greatest contribution of orthopedic surgery in the treatment of rheumatoid arthritis.
TL;DR: The possibility of a significant association between Hashimoto's thyroiditis and systemic lupus erythematosus is of considerable interest and evidence suggesting such an association is accumulating.
Abstract: The possibility of a significant association between Hashimoto's thyroiditis and systemic lupus erythematosus is of considerable interest. Two cases of coexisting Hashimoto's thyroiditis proved by biopsy and systemic lupus erythematosus proved by the clinical picture and positive lupus erythematosus clot tests contribute to accumulating evidence suggesting such an association.
TL;DR: X-ray examination is often helpful in establishing a diagnosis of acute appendicitis in infants and young children.
Abstract: X-ray examination is often helpful in establishing a diagnosis of acute appendicitis in infants and young children. An appendicolith is demonstrable in more than one-third of infants and at least h...
[...]
TL;DR: True petit mal epilepsy does not occur often, and strict clinical and electroencephalographic criteria should be used in diagnosis, but when systematic trial of anticonvulsant drug therapy fails, a ketogenic diet may be beneficial.
Abstract: True petit mal epilepsy does not occur often, and strict clinical and electroencephalographic criteria should be used in diagnosis. Ethosuximide and trimethadione are the most common and valuable drugs for treating petit mal, but when systematic trial of anticonvulsant drug therapy fails, a ketogenic diet may be beneficial.
TL;DR: With so many people traveling to areas of the country where coccidioidomycosis is endemic, recognizing this disease has become a matter of concern to physicians in every state.
Abstract: With so many people traveling to areas of the country where coccidioidomycosis is endemic, recognizing this disease has become a matter of concern to physicians in every state. A history of exposure is an essential clue in diagnosis, but absence from an endemic area for a considerable time does not exclude the possibility of the disease.
TL;DR: A calcium stone (about 90 percent of stones contain calcium) often signifies hypercalcemia; uric acid stone, accelerated nucleic acid breakdown; triple phosphate stone, urinary tract infection; and cystine or xanthine stone, inborn metabolic errors.
Abstract: Why analyze kidney stones? This is more than an academic question, for the answer may help the physician identify the source of the stone. A calcium stone (about 90 percent of stones contain calcium) often signifies hypercalcemia; uric acid stone, accelerated nucleic acid breakdown; triple phosphate stone, urinary tract infection; and cystine or xanthine stone, inborn metabolic errors.
TL;DR: When supporting tissues of the birth canal are weakened, genital prolapse may occur and only repair of the primary weakness can stem progression and prevent recurrence.
Abstract: When supporting tissues of the birth canal are weakened, genital prolapse may occur. Prolapse is seen as a manifestation of upper vaginal inversion, lower vaginal eversion, or both. The rate of progression may give clues to etiology and prognosis, but the physician must determine the site of primary damage. Only repair of the primary weakness can stem progression and prevent recurrence.
TL;DR: The psychologic response to last rites was investigated in a study of 30 patients hospitalized with a tentative diagnosis of myocardial infarction, and only four responded negatively.
Abstract: The psychologic response to last rites was investigated in a study of 30 patients hospitalized with a tentative diagnosis of myocardial infarction. Only four responded negatively. How the sacrament is administered seems to be the most important accessible variable affecting anxiety. It was most helpful when it was personal and specifically reassuring, stressed the routine nature of the procedure, and made reference to healing and recovery.
TL;DR: The Guillain-Barre syndrome has a slower onset, often follows a nonspecific illness, more commonly causes symmetrical paralysis, usually elevates the spinal fluid protein, may lead to sensory loss, tends to recur, and rarely results in permanent paralysis.
Abstract: Of the lower motor neuron diseases, poliomyelitis and Guillain-Barre syndrome are the most likely to be confused with one another. Yet the two diseases differ. The Guillain-Barre syndrome has a slower onset, often follows a nonspecific illness, more commonly causes symmetrical paralysis, usually elevates the spinal fluid protein, may lead to sensory loss, tends to recur, and rarely results in permanent paralysis.
TL;DR: The basis for the metyrapone test of pituitary function is described, and the carbon tetrachloride-extractable 11-DOCS response is superior to the 17-KGS or 17-OHCS end point.
Abstract: The basis for the metyrapone test of pituitary function is described. The carbon tetrachloride-extractable 11-DOCS response is superior to the 17-KGS or 17-OHCS end point. Patients with renal failure require a plasma 11-DOCS measurement for evaluation. Some patients with cirrhosis of the liver fail to give a normal plasma and urinary 11-DOCS response. Patients with Cushing's syndrome due to primary adrenal tumor give a subnormal 11-DOCS response, whereas those with adrenal hyperplasia respond normally.
TL;DR: Both petit mal and focal epilepsy should be included under the heading of familial idiopathic or centrencephalic epilepsy.
Abstract: Both petit mal and focal epilepsy should be included under the heading of familial idiopathic or centrencephalic epilepsy. Studies of representative families illustrate a spectrum of electroencephalographic abnormalities ranging from focal spike discharges (consistent or shifting) to petit mal types.
TL;DR: Percutaneous cordotomy is a technically safe and simple method of performing spinothalamic tractotomy that may be recommended for patients with bilateral pain or with pain due to nonmalignant disease and for those with some pulmonary impairment.
Abstract: Percutaneous cordotomy is a technically safe and simple method of performing spinothalamic tractotomy. It is ideally suited to the patient with normal lung function who has unilateral pain due to cancer. With some modifications and reservations, it may be recommended for patients with bilateral pain or with pain due to nonmalignant disease and for those with some pulmonary impairment.
TL;DR: Percutaneous transhepatic cholangiography proved a valuable procedure in managing 40 adults with unexplained jaundice and it is safe and reliable when done by an experienced radiologist under the proper conditions.
Abstract: Percutaneous transhepatic cholangiography proved a valuable procedure in managing 40 adults with unexplained jaundice. The procedure aids in identifying the site of extrahepatic biliary obstruction and the state of the biliary tree. It is safe and reliable when done by an experienced radiologist under the proper conditions.
TL;DR: Serum copper levels can be determined rapidly and accurately with atomic absorption spectrophotometry, and this will aid in earlier detection of Wilson's disease.
Abstract: Serum copper levels can be determined rapidly and accurately with atomic absorption spectrophotometry. Undoubtedly this will aid in earlier detection of Wilson's disease. There is also evidence that serial serum copper levels may be valuable in managing patients with Hodgkin's disease and acute leukemia.
TL;DR: Since allergy is so greatly affected by environment and emotions, the physician treating an allergy-prone patient should understand both.
Abstract: Since allergy is so greatly affected by environment and emotions, the physician treating an allergy-prone patient should understand both. Depending on the circumstances, humidity, air pollution, pollen, foods and drugs can provoke or aggravate allergy, just as can anger, worry or fear.