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Showing papers in "Veterinary Immunology and Immunopathology in 1985"



Journal ArticleDOI
TL;DR: Sera from several groups of experimental calves were tested for cytotoxin neutralizing capacity and resistance of the animals to an experimental challenge was examined, finding that undiluted bovine sera tested, other than fetal bovines serum, neutralized cytot toxin.

65 citations


Journal ArticleDOI
TL;DR: Horses inoculated with either equine cornea or killed Leptospira interrogans serovars pomona, tarassovi, icterohaemorrhagiae, wolffi and hardjo, developed corneal opacity and produced antibodies which made it possible to demonstrate partial antigenic identity between equine Cornea and four of those serovar employed.

58 citations


Journal ArticleDOI
TL;DR: The serum antibody response was determined to 6 antigen groups (AG's) derived from a saline extract of Pasteurella haemolytica, serotype 1, and it is suggested that antibody to polysaccharide antigens may be important to resistance.

51 citations


Journal ArticleDOI
TL;DR: In vitro intraphagocytic killing of Brucella abortus in bovine mononuclear leukocytes was enhanced by cationic, anionic, and neutral multilamellar liposomes-containing gentamicin.

50 citations


Journal ArticleDOI
TL;DR: The immunomodulating effect of two tetracycline analogues (oxytetracyCline and doxycycline) on mitogenic and allogeneic stimulation of carp (Cyprinus carpio) leukocytes in vitro is reported.

50 citations


Journal ArticleDOI
TL;DR: Intraperitoneal immunization of pigs with anti-African swine fever virus (ASFV) antibody protected them against the effects of challenge with ASFV, and experiments suggested that the reduction in viraemia was associated with complement lysis whereas protection was conferred by ADCC.

49 citations


Journal ArticleDOI
TL;DR: The results suggest that chronic flea exposure may result in partial or complete tolerance rather than hyposensitization in the commonly accepted sense.

48 citations


Journal ArticleDOI
TL;DR: Serum levels of IgM and IgG began a progressive postpartal decline during the 14th-17th week of gestation and continued to increase throughout lactation, reaching their highest serum levels in the third week of lactation; the serum IgA concentration at this time was twice that observed during the first 13 weeks of gestation.

47 citations


Journal ArticleDOI
TL;DR: The activation of macrophages and the stimulation of epidermal growth and keratinization are the processes induced by T-cell-mediated immunity which result in the resolution of systemic or cutaneous and mucosal disease.

41 citations


Journal ArticleDOI
TL;DR: Depression of serum IgA and IgM levels and elevated levels of IgG in all cases and Lectin transformation of lymphocytes in two dogs was found to be depressed relative to normal controls in case 1 and initially in case 2.

Journal ArticleDOI
TL;DR: Separated lymphocytes from untreated and selenium-supplemented lambs were tested in culture against phytolectins, finding that cells from both groups were more active in the presence of serum from supplemented animals, and a similar stimulatory effect was achieved by adding sodium selenite in vitro.

Journal ArticleDOI
TL;DR: BLV infection was followed by lymphocytosis of B- cells in most infected calves, which persisted for the whole course of the experiment, while a decrease in the population of T-cells in peripheral blood was observed for a period of several months in all infected calves.

Journal ArticleDOI
TL;DR: B26A is a pan-T lymphocyte MAb in cattle, a small but significant degree of heterogeneity exists in the expression of the epitopes recognized by H4 and TH21A and using a variety of immunological methods these three MAbs can now reliably be used to assay bovine T and B lymphocytes.

Journal ArticleDOI
TL;DR: In this article, the parameters of induction and assay of factors with IL-2 activity were examined in a group of clinically normal sheep seronegative for antibodies to ovine progressive pneumonia virus (OPPV-).

Journal ArticleDOI
TL;DR: A decreased lymphocyte response to all mitogens occurred early and became more severely depressed near death and IL-2 caused a complete or partial restoration of the response to the mitogens CON A and PHA.

Journal ArticleDOI
TL;DR: A model enzyme-linked immunosorbent assay (ELISA) system was developed which permits the user to evaluate replicate single sera dilutions of 46 test and control serum samples for the presence of specific antibody against up to eight different antigens in one assay.

Journal ArticleDOI
TL;DR: Saline extracts of logarithmic-phase Pasteurella haemolytica, serotype 1, were separated by chromatofocusing and six antigen groups (AG's) were identified, and each produced a characteristic pattern of proteins and antigens, although two antigenic proteins were common to all AG's.

Journal ArticleDOI
TL;DR: Investigation of the influence of age and breed on the concentrations of IgG, IgA and IgM in the sera of sows throughout the reproductive cycle found an increase in total immunoglobulins, IgM and IgG serum levels with increasing gestation number.

Journal ArticleDOI
TL;DR: Six monoclonal antibodies (Mabs) in ascitic fluids were characterized as to their reactivity with porcine immunoglobulin isotypes and all six Mabs were species-specific and recognized either of two antigenic regions of mu-chain.

Journal ArticleDOI
TL;DR: All the tests were found to be equally effective in assessing CMI response in chickens as determined by comparing the means of their performances.

Journal ArticleDOI
TL;DR: It can be urged that mycoplasmas would be less pathogenic if they did not produce an inflammatory response and some species have been shown to have an immunosuppressive effect.

Journal ArticleDOI
TL;DR: It is suggested that selenium deficiency may selectively impair LMIF production and hence the ability of lymphocytes to modulate neutrophil migration.

Journal ArticleDOI
TL;DR: Islet cell antibodies were demonstrated in dogs with diabetes mellitus and other endocrine disorders and the possibility of autoimmune involvement in the development ofabetes mellitus in the dog should be considered.

Journal ArticleDOI
TL;DR: The blastogenesis test in its present form is not recommend as a useful adjunct to serological tests, but could allow measurement of cell mediated immune responses relevant to protective immunity.

Journal ArticleDOI
TL;DR: Canine dendritic cells have been identified in peripheral blood and lymph nodes and have been shown to act as accessory cells in the response of lymphocytes to NGO and as stimulator cells in a one way mixed leukocyte culture (MLC).

Journal ArticleDOI
TL;DR: Human TCGF supported the continued growth of activated pig cells whereas mouse and sheep TCGF had no such effect and T cell growth factor prepared from pig blood cells in mixed lymphocyte culture had no effect on human activated cells.

Journal ArticleDOI
TL;DR: Concanavalin A (Con A) induced suppressor cell activity was evaluated in a group of ovine progressive pneumonia virus-antibody positive sheep (OPPV+) and sheep with OPP were found to be hypogammaglobulinemic.

Journal ArticleDOI
TL;DR: The results from a panel of sera from animals with a known status of vaccination or infection indicated that the test was more selective in the detection and discrimination of infected from uninfected or immunized animals, than conventional complement fixation, agglutination or indirect enzyme immunoassay procedures.

Journal ArticleDOI
TL;DR: Removal of G-10 adherent cells from the mononuclear cell population removed all antibody-dependent cellular cytotoxicity from that population, indicating the lack of a typical K cell in bovine peripheral blood.