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262. FSH and LH content of plasma after mitomycin treatment and the effect of the antibiotic on ovarian cellular constituents

C. Deb, +4 more
- 01 Sep 1978 - 
- Vol. 9, Iss: 9, pp 867
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This article is published in Journal of Steroid Biochemistry.The article was published on 1978-09-01. It has received 1 citations till now.

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Mitomycin C induced inhibition of adrenal steroidogenesis in female rats.

TL;DR: Mitomycin C (MC), an antibiotic which depresses DNA synthesis causes suppression of enzyme delta 5 3 beta-hydroxysteroid dehydrogenase and glucose-6 phosphate dehydration in the rat adrenal tissue, suggesting a diminution in adrenal steroid biogenesis similar to gonadal inhibition previously reported.
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Journal Article

Mitomycin C induced inhibition of adrenal steroidogenesis in female rats.

TL;DR: Mitomycin C (MC), an antibiotic which depresses DNA synthesis causes suppression of enzyme delta 5 3 beta-hydroxysteroid dehydrogenase and glucose-6 phosphate dehydration in the rat adrenal tissue, suggesting a diminution in adrenal steroid biogenesis similar to gonadal inhibition previously reported.
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