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951 twelve cases of toxic hepatitis related to the root of polygonum multiflorum thunb
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Traditional usages, botany, phytochemistry, pharmacology and toxicology of Polygonum multiflorum Thunb.: A review
TL;DR: A systematic review of the literature on Polygonum multiflorum was performed using several resources, including classic books on Chinese herbal medicine and various scientific databases, to provide comprehensive information on the botany, traditional uses, phytochemistry, pharmacological research and toxicology of this plant.
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Hepatoxicity of major constituents and extractions of Radix Polygoni Multiflori and Radix Polygoni Multiflori Praeparata
TL;DR: Wang et al. as mentioned in this paper studied the cytotoxicities of Radix Polygoni Multiflori (RPM) and their major constituents on human liver cell L-02 simultaneously.
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A novel method to analyze hepatotoxic components in Polygonum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry
TL;DR: The analysis methods suggest that PM toxicity may be associated with anthraquinone, emodin-O-(malonyl)-hex, emoda-O-glc, emodein, emmodin-8-O -glc), emod in-O"-acetyl-hex, and emodIn-O’-hex-sulphate.
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European medicinal and edible plants associated with subacute and chronic toxicity part II: Plants with hepato-, neuro-, nephro- and immunotoxic effects
Luka Kristanc,Samo Kreft +1 more
TL;DR: A systematic analysis of the subacute and chronic toxicity associated with the use of herbal preparations and the basic concepts regarding the molecular mechanisms implicated in their nonacute toxicity and their pathophysiological, clinical and epidemiological characteristics are included.
Journal ArticleDOI
In vivo hepatotoxicity screening of different extracts, components, and constituents of Polygoni Multiflori Thunb. in zebrafish (Danio rerio) larvae.
Hong-Ying Li,Jianbo Yang,Wan-Fang Li,Cai-Xia Qiu,Guang Hu,Shu-Ting Wang,Yun-Fei Song,Hui-Yu Gao,Yue Liu,Qi Wang,Ying Wang,Xian-Long Cheng,Feng Wei,Hong-Tao Jin,Shuang-Cheng Ma +14 more
TL;DR: This study is the first to identify that dianthrones may account for the hepatotoxicity of PM, and believes that these findings will be helpful in regulating the liver size, liver gray value, and the area of yolk sac.