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Journal ArticleDOI

A crystallographic examination of the structure of morphine

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This article is published in Journal of The Chemical Society (resumed).The article was published on 1955-01-01. It has received 52 citations till now.

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Journal ArticleDOI

The metabolism of morphine and heroin in man.

TL;DR: Theabolism of Morphine and Heroin in Man and Drug Metabolism Reviews: Vol.
Book ChapterDOI

Three-Dimensional Pharmacophoric Pattern Searching

Peter Gund
TL;DR: It is now clear that early attempts to correlate biologic activity quantitatively with chemical structure, using the Hammett equation or Huckel molecular orbital calculations, met with only limited success, due to the greater complexity of bioreactions compared to “normal” chemical reactions in homogeneous solution.
Journal ArticleDOI

Enantioselective synthesis of (-)-codeine and (-)-morphine.

TL;DR: A new synthetic strategy for the synthesis of the opiate and amaryllidaceae alkaloids emerges employing a Pd-catalyzed asymmetric allylic alkylation to set the stereochemistry.
Journal ArticleDOI

Evolution and current status of the phytochemistry of nitrogenous compounds.

TL;DR: Three classes of nitrogen-containing plant products are being reviewed in this article: the alkaloids, the cyanogenic glucosides/glucosinolates and the nonprotein amino acids.
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