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A Genetic Study of Human Breast Cancer

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This article is published in Journal of the National Cancer Institute.The article was published on 1972-04-01. It has received 140 citations till now. The article focuses on the topics: Breast cancer & Cancer.

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Journal ArticleDOI

Differentiation of the mammary gland and susceptibility to carcinogenesis

TL;DR: Induction of mammary cancer in rats by administration of the chemical carcinogen 7, 12-dimethylbenz(a)anthracene reveals that the same factors influencing human breast cancer risk also affect the susceptibility of the rat mammary gland to the chemicalcar carcinogen.
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Breast Cancer Epidemiology

TL;DR: Other areas of current research reviewed here include radiation, mammographic parenchymal patterns, a high-fat diet, use of oral contraceptives (OCs), use of estrogen replacement therapy, and endogenous hormones, which do not appear promising as potential etiologic agents.
Journal ArticleDOI

Allele loss on short arm of chromosome 17 in breast cancers.

TL;DR: In this article, the authors found that the highest frequency of allele loss (61%) was found with the probe YNZ22, which detects a sequence on the short arm of chromosome 17 (at p13.3).
Journal ArticleDOI

Effect of Family History, Body-Fat Distribution, and Reproductive Factors on the Risk of Postmenopausal Breast Cancer

TL;DR: The combined effect of family history and anthropometric and reproductive factors on the risk of breast cancer in postmenopausal women and the waist-to-hip ratio was examined to determine whether known risk factors for breast cancer are modified by a reported family history at the time of entry into the study.
Journal ArticleDOI

Family History and the Risk of Breast Cancer

TL;DR: The risk of breast cancer for a woman was higher if her first-degree relative had unilateral rather than bilateral breast cancer or had breast cancer detected at a younger rather than older age.
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