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Journal ArticleDOI

A novel rat model for tracheal mucosal damage assessment of following long term intubation.

TLDR
A novel rat-based animal model based on retrograde intubation via tracheotomy and suture fixation of the tube aims to simulate the common clinical scenario of tube-related airway damage due to long termintubation.
About
This article is published in International Journal of Pediatric Otorhinolaryngology.The article was published on 2020-01-01. It has received 2 citations till now. The article focuses on the topics: Intubation procedure & Intubation.

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Citations
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Journal ArticleDOI

Local Delivery of Mometasone Furoate from an Eluting Endotracheal Tube Reduces Airway Morbidity Following Long-Term Animal Intubation

TL;DR: This data indicates that systemic corticosteroids are a mainstay treatment for upper airway complications following endotracheal tube intubation, and drug-eluting ETT is a good option for these patients.
Book ChapterDOI

Impacts of nanotechnology in tissue engineering

TL;DR: In this article , the impact of nanotechnologies in terms of nanoparticles and nanomaterials in the skin, eye, and bone tissue engineering is discussed and the uses of biomaterials as nanomedicine in managing respiratory disease are also mentioned.
References
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Journal ArticleDOI

Prolonged Intubation Injuries of the Larynx: Endoscopic Diagnosis, Classification, And Treatment

TL;DR: In this paper, significant, severe, and lasting trauma of the larynx has been classified on the basis of the known factors in pathogenesis, observations made atendoscopy, and photographic documentation.
Journal ArticleDOI

Post-intubation laryngeal injuries and extubation failure: a fiberoptic endoscopic study

TL;DR: A high frequency of laryngeal injuries after extubation in ICU was found, which were associated with intubation duration and patient’s height/ETT size ratio and although edema is frequent it is not the only injury associated with reintubation.
Journal ArticleDOI

Protective effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, against streptozotocin-induced diabetes.

TL;DR: The protection exerted by 3-aminobenzamide against the diabetogenic effect of streptozotocin strongly supports the view that this acute effect may be a major consequence of the activation of DNA repair mechanisms in islet cells.
Journal ArticleDOI

Subglottic injury: a clinically relevant animal model.

TL;DR: To develop a clinically aligned, reproducible model for subglottic injury, a team of scientists and clinicians have used a novel, scalable, and reproducible approach called “big data” to solve the mystery of why deep vein thrombosis occurs in women.
Journal ArticleDOI

Protective Effect of 3-Aminobenzamide, an Inhibitor of Poly (ADP-Ribose) Synthetase, against Laryngeal Injury in Rats

TL;DR: It is suggested that poly (ADP-ribose) synthetase may play a role in the inflammatory process after laryngeal intubation and extubation, and administration of 3-aminobenzamide may be a beneficial therapeutic approach.
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