A potential role for psilocybin in the treatment of obsessive-compulsive disorder
Edward Jacobs,Edward Jacobs +1 more
- Vol. 4, Iss: 2, pp 77-87
TLDR
Although the current evidence is limited, that multiple signals point in directions consistent with treatment potential, alongside the psychological and physiological safety of clinically administered psilocybin, support the expansion of research, both in animal models and in further randomized controlled trials, to properly investigate this potential.Abstract:
The recent revivification of interest in the therapeutic use of psychedelics has had a particular focus on mood disorders and addiction, although there is reason to think these drugs may be effective more widely. After outlining pertinent aspects of psilocybin and obsessive-compulsive disorder (OCD), the current review summarizes the evidence indicating that there may be a role for psilocybin in the treatment of OCD, as well as highlighting a range of potential therapeutic mechanisms that reflect the action of psilocybin on brain function. Although the current evidence is limited, that multiple signals point in directions consistent with treatment potential, alongside the psychological and physiological safety of clinically administered psilocybin, support the expansion of research, both in animal models and in further randomized controlled trials, to properly investigate this potential.read more
Citations
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Diversity, biology, and history of psilocybin-containing fungi: Suggestions for research and technological development.
R. C. Van Court,Michele S. Wiseman,Kevin Wayne Meyer,Daniel J. Ballhorn,Kevin R. Amses,Jason C. Slot,Bryn T. M. Dentinger,Roberto Garibay-Orijel,Jessie K. Uehling +8 more
TL;DR: The use of psilocybin as a healing entheogen has a long history through traditional consumption of mushrooms from the genus Psilocybe, and their evolutionary history is discussed in this article .
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Psychedelic therapy for body dysmorphic disorder
Shevaugn Johnson,Chris Letheby +1 more
TL;DR: In this paper , the authors proposed the investigation of psychedelic-assisted psychotherapy for the treatment of body dysmorphic disorder (BDD), a psychiatric disorder characterised by appearance-based preoccupations and accompanying compulsions.
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