Journal ArticleDOI
A Simple Route to Benzo[b]xanthene-6,11,12-triones: Synthesis of Bikaverin
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A three-step procedure for the synthesis of 1H-benzo[b]xanthene-6,11,12-trione derivatives is described in this paper, which involves the halogenation of 12-(3-hydroxy-1,4-naphthoquinon-2-yl)-6H-hexanthene 6,11-(12H)-diones followed by treatment with water under aeration.Abstract:
A three-step procedure for the synthesis of 1H-benzo[b]xanthene-6,11,12-trione derivatives is described The procedure involves the halogenation of 12-(3-hydroxy-1,4-naphthoquinon-2-yl)-6H-benzo[b]xanthene-6,11-(12H)-diones, followed by treatment with water under aeration In this manner, bikaverin, a cytotoxic metabolite isolated from several species of the fungal genera Gibberella, Fusarium, and Mycogone, was synthesisedread more
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A convenient synthetic approach to dioncoquinone B and related compounds
TL;DR: In this article, a total synthesis of dioncoquinone B and related compounds, including ancistroquinones B, C and malvon A, is presented, based on available reagents and can be used as a preparative synthesis of a number of natural and synthetic biologically active (3-alkyl)-2,7,8-di(tri)methoxy(hydroxy)-1,4-naphthoquinones.
References
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Biosynthetic studies on the xanthone antibiotics lysolipins X and I
TL;DR: Feeding experiments with 13 C and 18 O-labeled precursors revealed that the polycyclic xanthone antibiotics, the lysolipins X and I, is derived from the polyketide pathway (12 malonate units), the C 1 pool (methionine), molecular oxygen, and the nitrogen pool.
Journal ArticleDOI
Chemistry of Naphthazarin Derivatives: XV.* Bromination of Naphthazarin and Its Derivatives
TL;DR: In this article, bromination of naphthazarin derivatives having different substituents in the aromatic ring with molecular bromine in carbon tetrachloride was studied.