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Journal ArticleDOI

A syndrome characterized by myokymia, myotonia, muscular wasting and increased perspiration.

Ingrid Gamstorp, +1 more
- 01 Jun 1959 - 
- Vol. 34, Iss: 2, pp 181-194
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TLDR
Electromyography shows repetitive usually normal action potentials corresponding to one or several units in each contracting part of muscles, which means that myokymia is produced by brief tetanic contractions2 in contrast to fasciculations, which are rapid twitches, accompanied by single, often large and polyphasicaction potentials.
Abstract
The term myokymia, which was introduced by Schultze (1895)l , is used to designate different syndromes. This has resulted in some confusion. The term should be reserved for spontaneous, relatively slow movements of parts of muscles. Different muscle regions move independently. giving the muscle surface an undulating appearance. Electromyography shows repetitive usually normal action potentials corresponding to one or several units in each contracting part. This means that myokymia is produced by brief tetanic contractions2 in contrast to fasciculations, which are rapid twitches, accompanied by single, often large and polyphasic action potentials. hlyokymia and fasciculation should not be confused with the quivering or flickering movements normally accurring in part of a muscle, which are known as “live flesh” and can be considered as a type of inyoclonias. Such movements are composed of a series of twitches, each corresponding to one large action potential. The series of twitches and concomitant potentials recur after intervals of wrying length in a stereotype way. The same muscle region is the site of such movements usually during a few days. Both these and other types of spontaneous muscle contractions have been designated as niyokymia in the literature. In some descriptions antedating the introduction of electromgography it is difficult to decide what type of movement is to be understood by the term myokymia. Generalized myokymin is rare and only few reports of it are on record ( 3 , 4 , 5, 6, i ) . I t is often combined with excessive sweating (3,1), and occasionally also with myotonia ( 5. 6. 7 ) .

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Citations
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Journal ArticleDOI

Hereditary myokymia and periodic ataxia

TL;DR: The myokymia described here is of interest not only because of its genetic association with a movement disorder, but also because the muscle findings support a peripheral basis for the muscle movements.
Journal ArticleDOI

Generalized muscular stiffness, fasciculations, and myokymia of peripheral nerve origin.

TL;DR: The muscular stiffness and continual EMG activity were abolished by curare but persisted during spinal anesthesia and after peripheral nerve blocks, suggesting that the syndrome was due to isolated, spontaneous, peripheral nerve hyperactivity.
Journal ArticleDOI

Hyperexcitability of motor and sensory neurons in neuromyotonia.

TL;DR: Two members of a family with a neuropathy resembling Charcot‐Marie‐Tooth disease were unable to relax their muscles after voluntary contraction, and muscle spasm often outlasted voluntary contraction by 30 seconds or more before subsiding into myokymia and fasciculations.
Journal ArticleDOI

AAEM minimonograph #44: diseases associated with excess motor unit activity.

TL;DR: Continuous muscle fiber activity (Isaacs' syndrome) comprises a heterogeneous group of hereditary and acquired disorders that cause hyperexcitability of peripheral nerves that are associated with electrophysiologic evidence of peripheral neuropathy and some are not.
References
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Journal ArticleDOI

Repetitive discharges in human motor nerve fibres during the post-ischaemic state

TL;DR: Experiments are described which have been made to establish the site of origin of spontaneous and induced repetitive discharges of repetitive muscle action-potentials, found mainly in the more distal muscles.
Journal ArticleDOI

BeitrÄge zur Muskelpathologie

Fr. Schultze
- 01 Dec 1894 - 
TL;DR: Dass bei gewisscn Nervenkrankheiten, besonders z.B. bei der Charco t ' schen Krankheit, ausgedehnte fibrilli~re und selbst fascicullire Zuckungen in the Musculatar vorkommca~ ist bekannt genug, scheint es aber zu sein.
Journal ArticleDOI

Familial periodic paralysis, myotonia, progressive amyotrophy, and pes cavus in members of a single family

TL;DR: The present communication has as its purpose the documentation of a family who demonstrate a large number of different myopathic disorders, and certain symptoms and signs presented suggest a combined heredity of myopathic and myelopathic or neuropathic disease.
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