Journal ArticleDOI
Absence of Tooth Staining With Doxycycline Treatment in Young Children
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TLDR
Findings indicate that treatment with doxycycline in children aged 2 to 8 years is not associated with tooth staining.Abstract:
The aim of the study was to determine if doxycycline causes tooth staining in young children. A dentist examined 31 randomized children who had been treated with doxycycline and 30 children who had not received doxycycline. Mean age of the children was 10.4 -/+ 2.1 years. Mean age at receipt of the first doxycycline treatment was 4.1 -/+ 1.6 years, and mean number of doxycycline courses was 2.0 -/+ 1.3. No tooth staining was detected by the dentist in any of the children in either group. These findings indicate that treatment with doxycycline in children aged 2 to 8 years is not associated with tooth staining.read more
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EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis
Åse Mygland,Unn Ljøstad,Volker Fingerle,Tobias A. Rupprecht,Erich Schmutzhard,Israel Steiner +5 more
TL;DR: Background: Lyme neuroborreliosis (LNB) is a nervous system infection caused by Borrelia burgdorferi sensu lato (Bb).
Journal ArticleDOI
Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis - United States.
Holly M. Biggs,Casey Barton Behravesh,Kristy K. Bradley,F. Scott Dahlgren,Naomi A. Drexler,J. Stephen Dumler,Scott M. Folk,Cecilia Y. Kato,R. Ryan Lash,Michael Levin,Robert F. Massung,Robert B. Nadelman,William L. Nicholson,Christopher D. Paddock,Bobbi S. Pritt,Marc S. Traeger +15 more
TL;DR: The CDC Rickettsial Zoonoses Branch developed this report to assist health care providers and public health professionals to recognize key epidemiologic features and clinical manifestations of tickborne rickettsial diseases, and understand that early empiric antibacterial therapy can prevent severe disease and death.
Journal ArticleDOI
Human Granulocytic Anaplasmosis
TL;DR: Human granulocytic anaplasmosis, a deer tick-transmitted rickettsial infection caused by Anaplasma phagocytophilum, is a common cause of undifferentiated fever in the northeast and upper Midwest United States.
Journal ArticleDOI
Murine Typhus: An Unrecognized Suburban Vectorborne Disease
Rachel Civen,Van Ngo +1 more
TL;DR: Serologic testing with the indirect immunofluorescence assay is the preferred diagnostic method and doxycycline is the antibiotic of choice and has been shown to shorten the course of illness.
The selection and use of essential medicines.
P Kazembe,JM Al-Fannah,Kalle Hoppu,Elizabeta Zisovska,Hanne Bak Pedersen,Suzanne Hill,C Ondari,D Terlouw,D Mattison,L Zhiping,D Mehta,AU Gilani,P Chongtrakul,Gregory L. Kearns,J Robertson,A Irs,EH Davies,N Cranswick,S Walters,H Coelho,A Helali,Hans V Hogerzeil,H Nakamura,Andy Gray,Marcus M. Reidenberg,S Suryawati,U Gupta +26 more
TL;DR: This report presents the recommendations of the WHO Expert Committee responsible for updating the WHO Model Lists of Essential Medicines, including a summary of the Committee's considerations and justifications for additions and changes to the Model Lists, including its recommendations.
References
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Journal ArticleDOI
Report of the Committee on Infectious Diseases
TL;DR: The Report of the Committee on Infectious Disease (ie, the so-called Red Book) is a source of essential information on the prevention, diagnosis, and treatment of pediatric infectious diseases.
Journal ArticleDOI
Rocky Mountain spotted fever.
TL;DR: Because there is no vaccine available against RMSF, avoidance of tick-infested areas is still the best way to prevent the infection.
Journal ArticleDOI
Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. erythromycin ethylsuccinate.
TL;DR: Clarithromycin and erythromycin were similarly effective and safe for the treatment of radiographically proved, community-acquired pneumonia in children older than 2 years old.
Journal ArticleDOI
Ambulatory Patients with Community-acquired Pneumonia: The Frequency of Atypical Agents and Clinical Course
Thomas J. Marrie,Rosanna W. Peeling,Michael J. Fine,Daniel E. Singer,Christopher M. Coley,Wishwa N. Kapoor +5 more
TL;DR: Both patients with atypical pneumonia and those with pneumonia of undetermined etiology suffered severe deterioration of physical functioning with a marked but incomplete recovery at 30 days, and nearly half the cases of ambulatory community-acquired pneumonia are due to "atypical" agents.
Journal ArticleDOI
Role of Mycoplasma pneumoniae and Chlamydia pneumoniae in Children with Community-Acquired Lower Respiratory Tract Infections
TL;DR: This study confirms that M. pneumoniae and/or C. pneumoniaE plays a significant role in community-acquired LRTIs in children of all ages and that such infections have a more complicated course when not treated with adequate antimicrobial agents.
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