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Journal ArticleDOI

Adverse reactions to intravenous agents in anaesthesia in France.

M. C. Laxenaire, +3 more
- 01 Sep 1982 - 
- Vol. 60, Iss: 17, pp 1006-1009
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TLDR
One hundred severe peranesthetic accidents occuring in hospitals in the eastern part of France were tested between 1975 and 1980 at the Immunological Unit of the University Hospital in Nancy, finding that predisposing factors, in the tested population, are found in a higher proportion than in the French population as a whole.
Abstract
One hundred severe peranesthetic accidents occuring in hospitals in the eastern part of France were tested between 1975 and 1980 at the Immunological Unit of the University Hospital in Nancy Tests were carried out “a posteriori”; mean time: three weeks after the accident (extremes: one week to one year) A second battery of tests was carried out in 35%, and a third one in 8% of the patients

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Citations
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Journal ArticleDOI

Anaphylaxis during anaesthesia. Results of a two‐year survey in France

TL;DR: Clinical reactions to neuromuscular blocking drugs were more severe than to latex, and the diagnostic value of specific IgE assays was confirmed, consistent with changes in the epidemiology of anaphylaxis related to anaesthesia.
Journal ArticleDOI

Suspected Anaphylactic Reactions Associated with Anaesthesia

TL;DR: This guidance recommends that all Departments of Anaesthesia should identify a Consultant Anaesthetist who is Clinical Lead for anaesthetic anaphylaxis, which is needed to recognise possible non-allergic causes for the ‘reaction’.
Journal ArticleDOI

Scandinavian Clinical Practice Guidelines on the diagnosis, management and follow-up of anaphylaxis during anaesthesia

TL;DR: These Scandinavian Clinical Practice Guidelines is to increase the awareness about anaphylaxis during anaesthesia amongst anaesthesiologists and it is hoped that increased focus on the subject will lead to prompt diagnosis, rapid and correct treatment, and standardised management of patients with anaphlyactic reactions during anaesthetic across Scandinavia.
Journal ArticleDOI

Allergic reactions occurring during anaesthesia

TL;DR: Since no specific treatment has been shown reliably to prevent the occurrence of anaphylaxis, allergy assessment must be performed in all high-risk patients and the need for proper epidemiological studies and the relative complexity of allergy investigation should be underscored.
References
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Journal ArticleDOI

Intradermal testing in the diagnosis of acute anaphylaxis during anaesthesia--results of five years experience.

TL;DR: Intradermal testing is of no value in the diagnosis of reactions to local anaesthetics or colloids but has great value in determining the cause of reactions due to induction agents or muscle relaxants if performed under controlled conditions.
Journal ArticleDOI

The human basophil degranulation test as an in vitro method for the diagnosis of allergies.

TL;DR: This very simple test explores the allergic sensitivity at the cellular level, probably through IgE‐dependent sensilization of the basophil, and positively correlates with histamine release and radioallergosorbent test (RAST).
Journal ArticleDOI

Anaphylaxis due to succinylcholine. Immunoallergological study of thirteen cases.

TL;DR: The antigen non‐specific release of histamine by synthetic neuromuscular blocking agents is well known, though a review of thirty‐two cases reported in the literature of anaphylactoid reactions to succinylcholine shows that there is insufficient evidence to determine whether the signs are due toAnaphylactic or to anaphyactic reactions.
Journal ArticleDOI

Reaginic antibodies to drugs used in anesthesia.

TL;DR: It was concluded that it is not possible to determine the mechanism of anaphylaxis from a history of previous exposure, and cross-sensitivity may be a factor in such reactions to muscle relaxants.
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